Ryosuke Masuda
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View article: Demonstration of the Formation of a Selenocysteine Selenenic Acid through Hydrolysis of a Selenocysteine Selenenyl Iodide Utilizing a Protective Molecular Cradle
Demonstration of the Formation of a Selenocysteine Selenenic Acid through Hydrolysis of a Selenocysteine Selenenyl Iodide Utilizing a Protective Molecular Cradle Open
Selenocysteine selenenic acids (Sec–SeOHs) and selenocysteine selenenyl iodides (Sec–SeIs) have long been recognized as crucial intermediates in the catalytic cycle of glutathione peroxidase (GPx) and iodothyronine deiodinase (Dio), respec…
View article: Cover Feature: Highly Electrophilic Intermediates in the Bypass Mechanism of Glutathione Peroxidase: Synthesis, Reactivity, and Structures of Selenocysteine‐Derived Cyclic Selenenyl Amides (Chem. Eur. J. 71/2023)
Cover Feature: Highly Electrophilic Intermediates in the Bypass Mechanism of Glutathione Peroxidase: Synthesis, Reactivity, and Structures of Selenocysteine‐Derived Cyclic Selenenyl Amides (Chem. Eur. J. 71/2023) Open
The cover picture shows key players in the catalytic cycle of the mammalian antioxidant enzyme, glutathione peroxidase (GPx). Selenocysteine selenenic acids (queen) and selenocysteine selenenyl sulfides (rook) are established contributors …
View article: CCDC 2251497: Experimental Crystal Structure Determination
CCDC 2251497: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Modeling Selenoprotein <i>Se</i>-Nitrosation: Synthesis of a <i>Se</i>-Nitrososelenocysteine with Persistent Stability
Modeling Selenoprotein <i>Se</i>-Nitrosation: Synthesis of a <i>Se</i>-Nitrososelenocysteine with Persistent Stability Open
The Se-nitrosation in selenoproteins such as glutathione peroxidase and thioredoxin reductase to produce Se-nitrososelenocysteines (Sec-SeNOs) has been proposed to play crucial roles in signaling processes mediated by reactive nitrogen spe…
View article: Stable cysteine sulfenic acid: synthesis by direct oxidation of a thiol, crystallographic analysis, and elucidation of reactivities
Stable cysteine sulfenic acid: synthesis by direct oxidation of a thiol, crystallographic analysis, and elucidation of reactivities Open
A small-molecule cysteine sulfenic acid (Cys–SOH) was synthesized and isolated as stable crystals, for the first time, by utilizing a nanosized molecular cavity as a protective cradle. The cradled Cys–SOH was synthesized by direct oxidatio…
View article: Automation on thermal control of blast furnace
Automation on thermal control of blast furnace Open
Accurate process control through automation is the key to achieving efficient and stable operation of a blast furnace. In this study, we developed an automatic control system of hot metal temperature (HMT). To cope with the slow and comple…
View article: Automatic Control of Hot Metal Temperature
Automatic Control of Hot Metal Temperature Open
To achieve the automation of blast furnace operation, an automatic control system for hot metal temperature (HMT) was developed. Nonlinear model predictive control (NMPC) which predicts up to ten-hour-ahead HMT and calculates appropriate c…
View article: An Operator Behavior Model for Thermal Control of Blast Furnace
An Operator Behavior Model for Thermal Control of Blast Furnace Open
To realize precise thermal control of a blast furnace, an operator model that imitates the behavior of skilled operators was developed using a convolutional neural network (CNN). Conventional thermal control systems suffer from large contr…
View article: Modeling the Catalytic Cycle of Glutathione Peroxidase by Nuclear Magnetic Resonance Spectroscopic Analysis of Selenocysteine Selenenic Acids
Modeling the Catalytic Cycle of Glutathione Peroxidase by Nuclear Magnetic Resonance Spectroscopic Analysis of Selenocysteine Selenenic Acids Open
Although selenocysteine selenenic acids (Sec-SeOHs) have been recognized as key intermediates in the catalytic cycle of glutathione peroxidase (GPx), examples of the direct observation of Sec-SeOH in either protein or small-molecule system…
View article: Isolable small-molecule cysteine sulfenic acid
Isolable small-molecule cysteine sulfenic acid Open
A small-molecule cysteine sulfenic acid (Cys–SOH) with ‘shelf stability’ protected by a molecular cradle was synthesized by direct oxidation of a thiol with H2O2. Its crystal structure and biologically relevant reactivity were elucidated.
View article: Information transmission through vibro-tactile stimulatoin on dorsum of hand
Information transmission through vibro-tactile stimulatoin on dorsum of hand Open
With the advancement of information technology, haptic devices are receiving attention over the last few years. However, transmission of detailed information, such as character information, by using haptic devices has not been achieved. Th…