Ryosuke Takeuchi
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View article: Thalamus–cortex interactions drive cell type-specific cortical development in human pluripotent stem cell-derived assembloids
Thalamus–cortex interactions drive cell type-specific cortical development in human pluripotent stem cell-derived assembloids Open
The thalamus plays a pivotal role in the development and function of neural circuits in the cerebral cortex. However, how thalamus–cortex interactions influence human cortical development remains unknown primarily because of the inaccessib…
View article: An extension module for a two-photon microscope enables flexible in vivo imaging and all-optical physiology
An extension module for a two-photon microscope enables flexible in vivo imaging and all-optical physiology Open
View article: Weak and Tunable Adhesion–Clutch Drives Rapid Cell Migration and Glioblastoma Invasion
Weak and Tunable Adhesion–Clutch Drives Rapid Cell Migration and Glioblastoma Invasion Open
To move forward, cells must exert backward forces against their surrounding environment. Recent studies have highlighted the importance of integrin‐independent forces for cell migration; however, the molecular machinery that exerts forces …
View article: Weak and tunable adhesion-clutch drives rapid cell migration and glioblastoma motility
Weak and tunable adhesion-clutch drives rapid cell migration and glioblastoma motility Open
SUMMARY To move forward, migrating cells must exert backward forces against the extracellular environment. Recent studies have highlighted the importance of integrin-independent forces for cell migration; but the molecular machinery that e…
View article: Conversion of silent synapses to AMPA receptor-mediated functional synapses in human cortical organoids
Conversion of silent synapses to AMPA receptor-mediated functional synapses in human cortical organoids Open
Despite the crucial role of synaptic connections and neural activity in the development and organization of cortical circuits, the mechanisms underlying the formation of functional synaptic connections in the developing human cerebral cort…
View article: Conversion of silent synapses to AMPA receptor-mediated functional synapses in human cortical organoids
Conversion of silent synapses to AMPA receptor-mediated functional synapses in human cortical organoids Open
Despite the crucial role of synaptic connections and neural activity in the development and organization of cortical circuits, the mechanisms underlying the formation of functional synaptic connections in the developing human cerebral cort…
View article: YORU: social behavior detection based on user-defined animal appearance using deep learning
YORU: social behavior detection based on user-defined animal appearance using deep learning Open
The creation of tools using deep learning methodologies for animal behavior analysis has revolutionized neuroethology. They allow researchers to analyze animal behaviors and reveal causal relationships between specific neural circuits and …
View article: Evolutionary engineering and characterization of Sendai virus mutants capable of persistent infection and autonomous production
Evolutionary engineering and characterization of Sendai virus mutants capable of persistent infection and autonomous production Open
Persistent virus infection involves modifying the host immune response and maintaining viral infection. Acute infection with Mononegavirales, such as Sendai viruses (SeVs), can give rise to viruses capable of persistent infection. SeVs est…
View article: Table of Contents
Table of Contents Open
View article: A mosaic adeno-associated virus vector as a versatile tool that exhibits high levels of transgene expression and neuron specificity in primate brain
A mosaic adeno-associated virus vector as a versatile tool that exhibits high levels of transgene expression and neuron specificity in primate brain Open
View article: Modeling the marmoset brain using embryonic stem cell-derived cerebral assembloids
Modeling the marmoset brain using embryonic stem cell-derived cerebral assembloids Open
Studying the non-human primate (NHP) brain is required for the translation of rodent research to humans, but remains a challenge for molecular, cellular, and circuit-level analyses in the NHP brain due to the lack of in vitro NHP brain sys…
View article: Subclinical and latent cardiac dysfunction in obstructive sleep apnea and effectiveness of continuous positive airway pressure
Subclinical and latent cardiac dysfunction in obstructive sleep apnea and effectiveness of continuous positive airway pressure Open
View article: Acute Myocardial Infarction Due to Coronary Artery Embolism during Chemotherapy with mFOLFOX-6 Plus Bevacizumab for Metastatic Colon Cancer
Acute Myocardial Infarction Due to Coronary Artery Embolism during Chemotherapy with mFOLFOX-6 Plus Bevacizumab for Metastatic Colon Cancer Open
Bevacizumab, a monoclonal antibody against vascular endothelial growth factor, may be associated with arterial embolisms. We herein report a case of acute myocardial infarction caused by coronary embolism during combination chemotherapy wi…
View article: Emergency Transcatheter Aortic Valve Implantation in a Surgical Aortic Bioprosthetic Valve for Acute Decompensated Heart Failure Caused by Sudden Progression of Structural Valve Deterioration
Emergency Transcatheter Aortic Valve Implantation in a Surgical Aortic Bioprosthetic Valve for Acute Decompensated Heart Failure Caused by Sudden Progression of Structural Valve Deterioration Open
Bioprosthetic aortic valves have limited durability. We herein report sudden progression of structural valve deterioration (SVD) and a successful case of emergency transcatheter aortic valve (TAV) implantation for acute decompensated heart…
View article: Posteromedial cortical networks encode visuomotor prediction errors.
Posteromedial cortical networks encode visuomotor prediction errors. Open
Predicting future events based on internal models is essential for animal survival. Predictive coding postulates that errors between prediction and observation in lower-order areas update predictions in higher-order areas through the hiera…
View article: Processing of visual statistics of naturalistic videos in macaque visual areas V1 and V4
Processing of visual statistics of naturalistic videos in macaque visual areas V1 and V4 Open
View article: Anatomical identification of segregated network modules of the retrosplenial cortex along the cingulate cortex
Anatomical identification of segregated network modules of the retrosplenial cortex along the cingulate cortex Open
The cingulate cortex, a brain region located from the genu of the corpus callosum to the splenium of the corpus callosum, is anatomically divided into anterior and posterior cingulate cortices (ACC and PCC, respectively). The ACC is involv…
View article: Development of a novel Brain-Machine Interface by wide-field microscopy
Development of a novel Brain-Machine Interface by wide-field microscopy Open
The Brain-Machine Interface (BMI) allows us to extend the human body and sensing by communication between external devices and brain. A study in monkeys (Nicolelis et al., 2000) showed that effective motor control signals to decode arm mov…
View article: A mosaic adeno-associated virus vector as a versatile tool that exhibits high levels of transgene expression and neuron specificity in primate brain
A mosaic adeno-associated virus vector as a versatile tool that exhibits high levels of transgene expression and neuron specificity in primate brain Open
Recent emphasis has been placed on gene transduction mediated through recombinant adeno-associated virus (AAV) vector to manipulate activity of neurons and their circuitry in the primate brain. In the present study, we created a novel AAV …
View article: Processing of Visual Statistics of Naturalistic Videos in Macaque Visual Areas V1 and V4
Processing of Visual Statistics of Naturalistic Videos in Macaque Visual Areas V1 and V4 Open
Natural scenes are characterized by diverse image statistics, including various parameters of the luminance histogram, outputs of Gabor-like filters, and pairwise correlations between the filter outputs of different positions, orientations…
View article: Difficulty Diagnosing Retrograde Type A Aortic Dissection with Intramural Hematoma and Risk of Re-dissection and Rupture: A Report of Two Cases
Difficulty Diagnosing Retrograde Type A Aortic Dissection with Intramural Hematoma and Risk of Re-dissection and Rupture: A Report of Two Cases Open
Acute type A aortic dissection is a potentially fatal disease, and emergency surgery should be considered when it is diagnosed. We herein report two cases of retrograde type A aortic dissection with intramural hematoma, followed by re-diss…
View article: Cover Image, Volume 529, Issue 8
Cover Image, Volume 529, Issue 8 Open
The cover image is based on the Research Article Cell type- and layerspecific convergence in core and shell neurons of the dorsal lateral geniculate nucleus by Sayumi Okigawa et al., https://doi.org/10.1002/cne.25075.
View article: Impact of remnant healthy pulp and apical tissue on outcomes after simulated regenerative endodontic procedure in rat molars
Impact of remnant healthy pulp and apical tissue on outcomes after simulated regenerative endodontic procedure in rat molars Open
View article: Cyclization Reaction-Based Turn-on Probe for Covalent Labeling of Target Proteins
Cyclization Reaction-Based Turn-on Probe for Covalent Labeling of Target Proteins Open
View article: Circuit mechanisms of spatial perception and visuomotor integration
Circuit mechanisms of spatial perception and visuomotor integration Open
Animals can make appropriate decisions based on sensory information about the environment. Vision is one of the most critical ability for survival in dynamic situations in nature, particularly for mammalian species, such as primates, carni…
View article: Study of cortical motor representation and cortical excitability in refractory neuropathic pain
Study of cortical motor representation and cortical excitability in refractory neuropathic pain Open
Objective: Repetitive transcranial magnetic stimulation over the primary motor cortex has been shown to provide an analgesic effect on refractory neuropathic pain. It is thought that the primary motor cortex may be involved in pain–related…
View article: Analyzing task-related neural activity with two-photon calcium imaging from behaving mice
Analyzing task-related neural activity with two-photon calcium imaging from behaving mice Open
Animals process and integrate sensory inputs to generate appropriate behavioral output. However, neural mechanisms underlying this process remain unclear. Here we established a short-term, visual discrimination task for head-fixed mice com…
View article: Electrochemical Study on the Extracellular Electron Transfer Pathway from Shewanella Strain Hac319 to Electrodes
Electrochemical Study on the Extracellular Electron Transfer Pathway from Shewanella Strain Hac319 to Electrodes Open
View article: P755Comparison of coagulation between radiofrequency and cryoballoon ablation for paroxysmal atrial fibrillation
P755Comparison of coagulation between radiofrequency and cryoballoon ablation for paroxysmal atrial fibrillation Open
View article: Effects of pulpotomy using mineral trioxide aggregate on prostaglandin transporter and receptors in rat molars
Effects of pulpotomy using mineral trioxide aggregate on prostaglandin transporter and receptors in rat molars Open