Ryota Ebata
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View article: Risk of malignancy in adult patients with congenital heart disease: a clinical practice review
Risk of malignancy in adult patients with congenital heart disease: a clinical practice review Open
This paper presents case studies of adult patients with congenital heart disease (CHD) who developed cancer and also discusses relevant epidemiological studies, risk factors, and reports on early detection. Herein, we describe three cases:…
View article: Treatment and prognosis of patients with Kawasaki disease and giant coronary artery aneurysm: a retrospective observational study
Treatment and prognosis of patients with Kawasaki disease and giant coronary artery aneurysm: a retrospective observational study Open
The prognosis of KD patients with GA was unsatisfactory in this study, especially in those with large and multiple GAs. In addition to antiplatelet therapy, we recommend continuation of strict anticoagulation therapy in these patients.
View article: A combination of VAP2 and SDF-1a as a candidate risk factor for coronary artery lesion formation in Kawasaki disease patients
A combination of VAP2 and SDF-1a as a candidate risk factor for coronary artery lesion formation in Kawasaki disease patients Open
View article: Asymmetric right ventricular myocardial work correlates with gold standard measurements of cardiac function in pulmonary hypertension
Asymmetric right ventricular myocardial work correlates with gold standard measurements of cardiac function in pulmonary hypertension Open
Right ventricular (RV) (dys)function determines outcomes in pulmonary hypertension (PH). We previously found that asymmetric RV myocardial work (MW) corresponds with inefficient RV function in experimental PH models. We therefore aimed to …
View article: Case Report: Identification of a CARD8 variant in all three patients with PFAPA syndrome complicated with Kawasaki disease
Case Report: Identification of a CARD8 variant in all three patients with PFAPA syndrome complicated with Kawasaki disease Open
Background Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA syndrome), and Kawasaki disease (KD) are both considered to be disorders of the innate immune system, and the potential role of inflammasome activati…
View article: Case report: Progressive pulmonary artery hypertension in a case of megalencephaly-capillary malformation syndrome
Case report: Progressive pulmonary artery hypertension in a case of megalencephaly-capillary malformation syndrome Open
Megalencephaly-capillary malformation syndrome (MCAP, OMIM # 602501) is caused by hyperactivity of the thephosphoinositide-3-kinase (PI3K)–Vakt murine thymoma viral oncogene homolog (AKT)–mammalian target of rapamycin (mTOR) pathway, which…
View article: Appropriate management of Kawasaki disease patients with coronary artery aneurysms: an interim report on a multicentric prospective registry study three years after commencement
Appropriate management of Kawasaki disease patients with coronary artery aneurysms: an interim report on a multicentric prospective registry study three years after commencement Open
The remote prognosis of patients with Kawasaki disease (KD) complicated by coronary artery aneurysms (CAA) is still unclear. The present, multicentric registry study aimed to study the factors associated with coronary events (CE) and deter…
View article: Reproducibility between three-dimensional turbo spin-echo and two-dimensional dual inversion recovery turbo spin-echo for coronary vessel wall imaging in Kawasaki disease
Reproducibility between three-dimensional turbo spin-echo and two-dimensional dual inversion recovery turbo spin-echo for coronary vessel wall imaging in Kawasaki disease Open
View article: Reproducibility Between Three-Dimensional Turbo Spin-Echo and Two-Dimensional Dual Inversion Recovery Turbo Spin-Echo for Coronary Vessel Wall Imaging in Kawasaki Disease
Reproducibility Between Three-Dimensional Turbo Spin-Echo and Two-Dimensional Dual Inversion Recovery Turbo Spin-Echo for Coronary Vessel Wall Imaging in Kawasaki Disease Open
Background: Magnetic resonance vessel wall imaging is desirable for evaluating Kawasaki disease (KD)-associated coronary arterial lesions. Purpose: To evaluate reproducibility of three-dimensional turbo spin-echo (3D-TSE) and two-dimension…
View article: Sivelestat sodium hydrate treatment for refractory Kawasaki disease
Sivelestat sodium hydrate treatment for refractory Kawasaki disease Open
Background There is still no definite treatment for refractory Kawasaki disease ( KD ). In this pilot study, we evaluated the safety and efficacy of a new protocol consisting of sivelestat sodium hydrate ( SSH ) combined with additional i.…
View article: 307. EFFICACY OF PRIMARY TREATMENT WITH IMMUNOGLOBULIN PLUS CYCLOSPORINE FOR PREVENTION OF CORONARY ARTERY ABNORMALITIES IN KAWASAKI DISEASE PATIENTS PREDICTED TO BE AT INCREASED RISK OF IVIG NON- RESPONSE (KAICA STUDY): A CONTROLLED, PHASE 3, RANDOMISED, OPEN-LABEL, BLINDED-ENDPOINTS TRIAL
307. EFFICACY OF PRIMARY TREATMENT WITH IMMUNOGLOBULIN PLUS CYCLOSPORINE FOR PREVENTION OF CORONARY ARTERY ABNORMALITIES IN KAWASAKI DISEASE PATIENTS PREDICTED TO BE AT INCREASED RISK OF IVIG NON- RESPONSE (KAICA STUDY): A CONTROLLED, PHASE 3, RANDOMISED, OPEN-LABEL, BLINDED-ENDPOINTS TRIAL Open
View article: Nationwide Survey of Patients With Giant Coronary Aneurysm Secondary to Kawasaki Disease 1999–2010 in Japan
Nationwide Survey of Patients With Giant Coronary Aneurysm Secondary to Kawasaki Disease 1999–2010 in Japan Open
Severe cardiac events are likely to occur within 2 years from onset of Kawasaki disease, while no deaths occurred beyond this time. Hence, careful monitoring is needed especially for the first 2 years. Most patients with giant coronary ane…
View article: Additional file 1: Table S1. of A novel KCNQ1 nonsense variant in the isoform-specific first exon causes both jervell and Lange-Nielsen syndrome 1 and long QT syndrome 1: a case report
Additional file 1: Table S1. of A novel KCNQ1 nonsense variant in the isoform-specific first exon causes both jervell and Lange-Nielsen syndrome 1 and long QT syndrome 1: a case report Open
The probandâ s (II-2 in Fig. 2) results of genetic screening of LQT causative genes (KCNQ1, KCNH2, SCN5A, KCNE1, KCNE2, KCNJ2, SCN4B, KCNJ5). Entire coding exons, including the intronic boundaries of the genes were analyzed. (XLSX 10 kb)
View article: Variations in ORAI1 Gene Associated with Kawasaki Disease
Variations in ORAI1 Gene Associated with Kawasaki Disease Open
Kawasaki disease (KD; MIM#61175) is a systemic vasculitis syndrome with unknown etiology which predominantly affects infants and children. Recent findings of susceptibility genes for KD suggest possible involvement of the Ca(2+)/NFAT pathw…
View article: Study protocol for a phase III multicentre, randomised, open-label, blinded-end point trial to evaluate the efficacy and safety of immunoglobulin plus cyclosporin A in patients with severe Kawasaki disease (KAICA Trial)
Study protocol for a phase III multicentre, randomised, open-label, blinded-end point trial to evaluate the efficacy and safety of immunoglobulin plus cyclosporin A in patients with severe Kawasaki disease (KAICA Trial) Open
Introduction Kawasaki disease (KD) is an acute, self-limited vasculitis of unknown aetiology that predominantly affects infants and young children. We hypothesise that cyclosporin A (CsA) may be effective in treating KD by regulating the C…