Ryuichiro Hashimoto
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View article: Category-Specific Brain Structural Changes in Psychiatric Disorders and Conditions Using Well-Qualified Harmonization Dataset from Multiple Sites
Category-Specific Brain Structural Changes in Psychiatric Disorders and Conditions Using Well-Qualified Harmonization Dataset from Multiple Sites Open
Background Large-scale, multi-site brain magnetic resonance imaging (MRI) studies have revealed neuroanatomical alterations in various psychiatric disorders. However, site-specific differences—such as sampling and measurement biases—and th…
View article: Iron deposition and functional connectivity alterations in the right substantia nigra of adult males with autism
Iron deposition and functional connectivity alterations in the right substantia nigra of adult males with autism Open
The substantia nigra (SN) is a midbrain nucleus implicated not only in motor control and reward processing but also in higher-order cognitive functions. Iron homeostasis in this region is essential for neurotransmitter synthesis, especiall…
View article: Unsupervised feature computation-based feature selection robustly extracted resting-state functional connectivity patterns related to mental disorders
Unsupervised feature computation-based feature selection robustly extracted resting-state functional connectivity patterns related to mental disorders Open
Research on biomarkers for predicting psychiatric disorders from resting-state functional connectivity (FC) is advancing. While the focus has primarily been on the discriminative performance of biomarkers by machine learning, identificatio…
View article: Sensory seeking and its influence on sustained attention performance in adult males with Autism Spectrum Condition
Sensory seeking and its influence on sustained attention performance in adult males with Autism Spectrum Condition Open
Atypical sensory responses and seeking behaviors constitute the core symptoms of autism spectrum condition (ASC). There are possible links between atypical sensory profiles and attentional challenges in ASC. Due to the paucity of studies i…
View article: Electroencephalography-guided transcranial direct current stimulation improves picture-naming performance
Electroencephalography-guided transcranial direct current stimulation improves picture-naming performance Open
Transcranial direct current stimulation (tDCS) is a potential method for improving verbal function by stimulating Broca's area. Previous studies have shown the effectiveness of using functional magnetic resonance imaging (fMRI) to optimize…
View article: Generalizable and transportable resting-state neural signatures characterized by functional networks, neurotransmitters, and clinical symptoms in autism
Generalizable and transportable resting-state neural signatures characterized by functional networks, neurotransmitters, and clinical symptoms in autism Open
Autism spectrum disorder (ASD) is a lifelong condition with elusive biological mechanisms. The complexity of factors, including inter-site and developmental differences, hinders the development of a generalizable neuroimaging classifier fo…
View article: Functional alterations of lateral temporal cortex for processing voice prosody in adults with autism spectrum disorder
Functional alterations of lateral temporal cortex for processing voice prosody in adults with autism spectrum disorder Open
The human auditory system includes discrete cortical patches and selective regions for processing voice information, including emotional prosody. Although behavioral evidence indicates individuals with autism spectrum disorder (ASD) have d…
View article: Comprehensive evaluation of pipelines for diagnostic biomarkers of major depressive disorder using multi-site resting-state fMRI datasets
Comprehensive evaluation of pipelines for diagnostic biomarkers of major depressive disorder using multi-site resting-state fMRI datasets Open
The objective diagnostic and stratification biomarkers developed with resting-state functional magnetic resonance imaging (rs-fMRI) data are expected to contribute to more effective treatment for mental disorders. Unfortunately, there are …
View article: Meta-analysis of structural integrity of white matter and functional connectivity in developmental stuttering
Meta-analysis of structural integrity of white matter and functional connectivity in developmental stuttering Open
Developmental stuttering is a speech disfluency disorder characterized by repetitions, prolongations, and blocks of speech. While a number of neuroimaging studies have identified alterations in localized brain activation during speaking in…
View article: Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification
Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification Open
Differential diagnosis is sometimes difficult in practical psychiatric settings, in terms of using the current diagnostic system based on presenting symptoms and signs. The creation of a novel diagnostic system using objective biomarkers i…
View article: Generalizable neuromarker for autism spectrum disorder across imaging sites and developmental stages: A multi-site study
Generalizable neuromarker for autism spectrum disorder across imaging sites and developmental stages: A multi-site study Open
Autism spectrum disorder (ASD) is a lifelong condition, and its underlying biological mechanisms remain elusive. The complexity of various factors, including inter-site and development-related differences, makes it challenging to develop g…
View article: Distinctive alterations in the mesocorticolimbic circuits in various psychiatric disorders
Distinctive alterations in the mesocorticolimbic circuits in various psychiatric disorders Open
Aim Increasing evidence suggests that psychiatric disorders are linked to alterations in the mesocorticolimbic dopamine‐related circuits. However, the common and disease‐specific alterations remain to be examined in schizophrenia (SCZ), ma…
View article: Subcortical volumetric alterations in four major psychiatric disorders: A mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification
Subcortical volumetric alterations in four major psychiatric disorders: A mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification Open
Subcortical brain structures are the hubs for various psycho-behavioral functions. There is no mega-analysis to simultaneously investigate subcortical volumetric alterations in schizophrenia, bipolar disorder, major depressive disorder, an…
View article: Intergroup bias in punishing behaviors of adults with autism spectrum disorder
Intergroup bias in punishing behaviors of adults with autism spectrum disorder Open
Groups are essential elements of society, and humans, by nature, commonly manifest intergroup bias (i.e., behave more positively toward an ingroup member than toward an outgroup member). Despite the growing evidence of various types of alt…
View article: Decision flexibilities in autism spectrum disorder: an fMRI study of moral dilemmas
Decision flexibilities in autism spectrum disorder: an fMRI study of moral dilemmas Open
People make flexible decisions across a wide range of contexts to resolve social or moral conflicts. Individuals with autism spectrum disorder (ASD) frequently report difficulties in such behaviors, which hinders the flexibility in changin…
View article: Effects of upgrading acquisition-techniques and harmonization methods: A multi-modal MRI study with implications for longitudinal designs
Effects of upgrading acquisition-techniques and harmonization methods: A multi-modal MRI study with implications for longitudinal designs Open
A downside of upgrading MRI acquisition sequences is the discontinuity of technological homogeneity of the MRI data. It hampers combining new and old datasets, especially in a longitudinal design. Characterizing upgrading effects on multip…
View article: Prediction of life satisfaction from resting‐state functional connectome
Prediction of life satisfaction from resting‐state functional connectome Open
Background Better life satisfaction (LS) is associated with better psychological and psychiatric outcomes. To the best of our knowledge, no studies have examined prediction models for LS. Methods Using resting‐state functional magnetic res…
View article: Common Brain Networks Between Major Depressive-Disorder Diagnosis and Symptoms of Depression That Are Validated for Independent Cohorts
Common Brain Networks Between Major Depressive-Disorder Diagnosis and Symptoms of Depression That Are Validated for Independent Cohorts Open
Large-scale neuroimaging data acquired and shared by multiple institutions are essential to advance neuroscientific understanding of pathophysiological mechanisms in psychiatric disorders, such as major depressive disorder (MDD). About 75%…
View article: Development of Metacognition in Adolescence: The Congruency-Based Metacognition Scale
Development of Metacognition in Adolescence: The Congruency-Based Metacognition Scale Open
Introduction Previous studies on metacognitive ability were explored using self-report questionnaires that are difficult to adequately measure and evaluate when the capacity for self-reference is undeveloped. This study aimed to validate t…