Daniel Pérez
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View article: Assessing the clinical and cost-effectiveness of endovascular vs open revascularisation in severe occlusive aorto-iliac disease (EVOCC trial): study protocol for a randomised controlled trial
Assessing the clinical and cost-effectiveness of endovascular vs open revascularisation in severe occlusive aorto-iliac disease (EVOCC trial): study protocol for a randomised controlled trial Open
Introduction Severe aorto-iliac steno-occlusive atherosclerotic disease is a major cause of morbidity and amputation in patients with peripheral arterial disease. While both open surgical and endovascular revascularisation are standard tre…
View article: Rescuing the heart from tamponade with emergent ultrasound-guided pericardiocentesis: A case report
Rescuing the heart from tamponade with emergent ultrasound-guided pericardiocentesis: A case report Open
We highlighted the importance of early diagnosis and ultrasound-guided pericardiocentesis in acute cardiac tamponade.
View article: Indications of <i>Helicobacter pylori</i> Eradication Treatment and Its Influence on Prescriptions and Effectiveness (Hp‐<scp>EuReg</scp>)
Indications of <i>Helicobacter pylori</i> Eradication Treatment and Its Influence on Prescriptions and Effectiveness (Hp‐<span>EuReg</span>) Open
Background The influence of indications for Helicobacter pylori investigation on prescriptions and effectiveness is unknown. The aim of the study was to assess the impact of indications for H. pylori investigation on prescriptions, effecti…
View article: The postsurgical pancreas
The postsurgical pancreas Open
Background Partial pancreatic resections are among the most complex surgical procedures in visceral tumor medicine and are associated with a high postoperative morbidity with a complication rate of 40–50 % of patients even in specialized c…
View article: Surgical Management of Complex Multiligament Knee Injury: Case Report
Surgical Management of Complex Multiligament Knee Injury: Case Report Open
Multiligament knee injuries (MLKIs) frequently require immediate intervention to prevent severe complications, including vascular injury. We present the case of a 51‐year‐old male who sustained a traumatic right knee dislocation following …
View article: Lymphatic Mapping in Colon Cancer Depending on Injection Time and Tracing Agent: A Systematic Review and Meta-Analysis of Prospective Designed Studies
Lymphatic Mapping in Colon Cancer Depending on Injection Time and Tracing Agent: A Systematic Review and Meta-Analysis of Prospective Designed Studies Open
An optimized lymph node yield leads to better survival in colon cancer, but extended lymphadenectomy is not associated with survival benefits. Lymphatic mapping shows several colon cancers feature aberrant drainage pathways inducing local …
View article: IL-22BP controls the progression of liver metastasis in colorectal cancer
IL-22BP controls the progression of liver metastasis in colorectal cancer Open
Background The immune system plays a pivotal role in cancer progression. Interleukin 22 binding protein (IL-22BP), a natural antagonist of the cytokine interleukin 22 (IL-22) has been shown to control the progression of colorectal cancer (…
View article: Initial learning curves of laparoscopic and robotic distal pancreatectomy compared with open distal pancreatectomy: multicentre analysis
Initial learning curves of laparoscopic and robotic distal pancreatectomy compared with open distal pancreatectomy: multicentre analysis Open
Journal Article Initial learning curves of laparoscopic and robotic distal pancreatectomy compared with open distal pancreatectomy: multicentre analysis Get access Felix Nickel, Felix Nickel Department of General, Visceral, and Transplanta…
View article: The morphology of CS Cha circumbinary disk suggesting the existence of a Saturn-mass planet
The morphology of CS Cha circumbinary disk suggesting the existence of a Saturn-mass planet Open
Context. Planets have been detected in circumbinary orbits in several different systems, despite the additional challenges faced during their formation in such an environment. Aims. We investigate the possibility of planetary formation in …
View article: Robotic-assisted minimally invasive Ivor Lewis esophagectomy within the prospective multicenter German da Vinci Xi registry trial
Robotic-assisted minimally invasive Ivor Lewis esophagectomy within the prospective multicenter German da Vinci Xi registry trial Open
Purpose Robotic-assisted minimally invasive esophagectomy (RAMIE) has become one standard approach for the operative treatment of esophageal tumors at specialized centers. Here, we report the results of a prospective multicenter registry f…
View article: Mucin 5AC expression is common but unrelated to tumor progression in pancreatic adenocarcinoma
Mucin 5AC expression is common but unrelated to tumor progression in pancreatic adenocarcinoma Open
Introduction: Mucin 5AC (MUC5AC) belongs to the family of secreted gel-forming mucins. It is physiologically expressed in some normal mucin producing epithelial cells but also in pancreatic, ovarian, and colon cancer cells. The role of MUC…
View article: Risk stratification of cirrhotic patients undergoing esophagectomy for esophageal cancer: A single-centre experience
Risk stratification of cirrhotic patients undergoing esophagectomy for esophageal cancer: A single-centre experience Open
Background Concomitant liver cirrhosis is a crucial risk factor for major surgeries. However, only few data are available concerning cirrhotic patients requiring esophagectomy for malignant disease. Methods From a prospectively maintained …
View article: CD147 expression lacks prognostic relevance in esophageal cancer
CD147 expression lacks prognostic relevance in esophageal cancer Open
Introduction The role of CD147 as an important indicator of tumor prognosis remains controversially discussed in literature. We focused on the prognostic significance of CD147 expression in esophageal cancer patients. While some studies re…
View article: Angiotensin-Converting Enzyme 2 Protein Is Overexpressed in a Wide Range of Human Tumour Types: A Systematic Tissue Microarray Study on >15,000 Tumours
Angiotensin-Converting Enzyme 2 Protein Is Overexpressed in a Wide Range of Human Tumour Types: A Systematic Tissue Microarray Study on >15,000 Tumours Open
Angiotensin-converting enzyme 2 (ACE2) is a regulator in the renin-angiotensin system. ACE2 expression was analysed immunohistochemically in 15,306 samples from 119 tumour types and in 608 samples of 76 normal tissue types. In normal tissu…
View article: Robotic rectal resection preserves anorectal function: Systematic review and meta‐analysis
Robotic rectal resection preserves anorectal function: Systematic review and meta‐analysis Open
Background Improving survival rates in rectal cancer patients has generated a growing interest in functional outcomes after total mesorectal excision (TME). The well‐established low anterior resection syndrome (LARS) score assesses postope…
View article: Robotic-assisted minimally invasive esophagectomy (RAMIE) for esophageal cancer training curriculum—a worldwide Delphi consensus study
Robotic-assisted minimally invasive esophagectomy (RAMIE) for esophageal cancer training curriculum—a worldwide Delphi consensus study Open
Summary Background Structured training protocols can safely improve skills prior initiating complex surgical procedures such as robotic-assisted minimally invasive esophagectomy (RAMIE). As no consensus on a training curriculum for RAMIE h…
View article: Peer Review #2 of "DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness (v0.2)"
Peer Review #2 of "DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness (v0.2)" Open
Background.DOG1 (ANO1; TMEM16A) is a voltage-gated calcium-activated chloride and bicarbonate channel.DOG1 is physiologically expressed in Cajal cells, where it plays an important role in regulating intestinal motility and its expression i…
View article: Peer Review #1 of "DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness (v0.1)"
Peer Review #1 of "DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness (v0.1)" Open
Background.DOG1 (ANO1; TMEM16A) is a voltage-gated calcium-activated chloride and bicarbonate channel.DOG1 is physiologically expressed in Cajal cells, where it plays an important role in regulating intestinal motility and its expression i…
View article: DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness
DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness Open
Background DOG1 (ANO1; TMEM16A) is a voltage-gated calcium-activated chloride and bicarbonate channel. DOG1 is physiologically expressed in Cajal cells, where it plays an important role in regulating intestinal motility and its expression …
View article: Peer Review #2 of "DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness (v0.1)"
Peer Review #2 of "DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness (v0.1)" Open
Background.DOG1 (ANO1; TMEM16A) is a voltage-gated calcium-activated chloride and bicarbonate channel.DOG1 is physiologically expressed in Cajal cells, where it plays an important role in regulating intestinal motility and its expression i…
View article: Risk Stratification of Cirrhotic Patients Undergoing Esophagectomy for Esophageal Cancer: A Single-Centre Experience
Risk Stratification of Cirrhotic Patients Undergoing Esophagectomy for Esophageal Cancer: A Single-Centre Experience Open
Concomitant liver cirrhosis is a crucial risk factor for major surgeries. However, only few data are available concerning cirrhotic patients requiring esophagectomy for malignant disease. From a prospectively maintained database of esophag…