Ann‐Sofie Sandberg
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View article: Influence of Sourdough Fermentation-Induced Dephytinization on Iron Absorption from Whole Grain Rye Bread–Double-Isotope Crossover and Single-Blind Absorption Studies
Influence of Sourdough Fermentation-Induced Dephytinization on Iron Absorption from Whole Grain Rye Bread–Double-Isotope Crossover and Single-Blind Absorption Studies Open
Background/Objectives: There are substantial beneficial health effects from a diet rich in whole grains. However, a high intake of whole grain, and hence a high intake of the iron absorption inhibitor phytate, may result in the impaired bi…
View article: Food and nutrient intake at 1 year of age in Northern Sweden: results from the Swedish NICE birth cohort
Food and nutrient intake at 1 year of age in Northern Sweden: results from the Swedish NICE birth cohort Open
Dietary habits and nutrient intake early in life are important for long-term health. Here, we examine food and nutrient intake at 1 year of age in the Swedish NICE (Nutritional impact on Immunological maturation during Childhood in relatio…
View article: Fermented Quinoa and Canihua in Plant‐Based Diets Increase Iron and Zinc Bioavailability in Growing Rats
Fermented Quinoa and Canihua in Plant‐Based Diets Increase Iron and Zinc Bioavailability in Growing Rats Open
This study aimed at evaluating the effects of non‐fermented and fermented pseudocereal flours, quinoa and canihua, on iron and zinc bioavailability in Wistar rats. Two diets prepared with 92% fermented quinoa or 79.5% fermented canihua wer…
View article: Associations of gestational and childhood exposure to lead, cadmium, and fluoride with cognitive abilities, behavior, and social communication at 4 years of age: NICE birth cohort study
Associations of gestational and childhood exposure to lead, cadmium, and fluoride with cognitive abilities, behavior, and social communication at 4 years of age: NICE birth cohort study Open
Despite non-significant associations, both lead and cadmium exposure showed consistent inverse associations with cognitive abilities at 4 years, whereas associations with behavioral problems were less conclusive, especially for cadmium. Re…
View article: In vitro protein digestibility and mineral accessibility of edible filamentous Fungi cultivated in oat flour
In vitro protein digestibility and mineral accessibility of edible filamentous Fungi cultivated in oat flour Open
Edible filamentous fungi, a source of mycoprotein, are one of the sustainable alternative protein. This study compares protein digestibility (DH%) and amino acid and mineral accessibility in Rhizopus oligosporus cultivated in oat flour (Oa…
View article: Biomarker Candidates of Habitual Food Intake in a Swedish Cohort of Pregnant and Lactating Women and Their Infants
Biomarker Candidates of Habitual Food Intake in a Swedish Cohort of Pregnant and Lactating Women and Their Infants Open
Circulating food metabolites could improve dietary assessments by complementing traditional methods. Here, biomarker candidates of food intake were identified in plasma samples from pregnancy (gestational week 29, N = 579), delivery (mothe…
View article: Short-chain fatty acids (SCFA) in infants’ plasma and corresponding mother’s milk and plasma in relation to subsequent sensitisation and atopic disease
Short-chain fatty acids (SCFA) in infants’ plasma and corresponding mother’s milk and plasma in relation to subsequent sensitisation and atopic disease Open
Swedish Research Council (Nr. 2013-3145, 2019-0137 and 2023-02217 to A-S.S.), Swedish Research Council for Health, Working Life and Welfare FORTE, Nr 2018-00485 to A.W.), The Swedish Asthma and Allergy Association's Research Fund (2020-002…
View article: Toxic metals and essential trace elements in placenta and their relation to placental function
Toxic metals and essential trace elements in placenta and their relation to placental function Open
Among the toxic metals, lead appeared to negatively impact placental weight and cobalt decreased placental mtDNAcn. Joint essential element concentrations increased placental mtDNAcn. Manganese also appeared to increase placental weight, b…
View article: Data-driven analysis and prediction of dynamic postprandial metabolic response to multiple dietary challenges using dynamic mode decomposition
Data-driven analysis and prediction of dynamic postprandial metabolic response to multiple dietary challenges using dynamic mode decomposition Open
Motivation In the field of precision nutrition, predicting metabolic response to diet and identifying groups of differential responders are two highly desirable steps toward developing tailored dietary strategies. However, data analysis to…
View article: LC-MS-Based Metabolomics for Dietary Biomarker Discovery in a Cohort of Pregnant and Lactating Women and Their Infants
LC-MS-Based Metabolomics for Dietary Biomarker Discovery in a Cohort of Pregnant and Lactating Women and Their Infants Open
Circulating food metabolites could improve dietary assessment by complementing more traditional, subjective methods. However, information is lacking on the accuracy of these objective markers during pregnancy and lactation. The objective o…
View article: Analysis and Prediction of Postprandial Metabolic Response to Multiple Dietary Challenges Using Dynamic Mode Decomposition
Analysis and Prediction of Postprandial Metabolic Response to Multiple Dietary Challenges Using Dynamic Mode Decomposition Open
Background: In the field of precision nutrition, predicting high-dimensional metabolic response to diet and identifying groups of differential responders are two highly desirable steps towards developing tailored dietary strategies. Howeve…
View article: Interaction of Iron Homeostasis and Fatty Acid Metabolism in the Development of Glucose Intolerance in Women with Previous Gestational Diabetes Mellitus
Interaction of Iron Homeostasis and Fatty Acid Metabolism in the Development of Glucose Intolerance in Women with Previous Gestational Diabetes Mellitus Open
A gestational diabetes mellitus (GDM) diagnosis during pregnancy means an increased risk of developing type 2 diabetes later in life. By following up with women after GDM we aimed to examine the relationship between iron parameters, indivi…
View article: Associations of the placental metabolome with immune maturation up to one year of age in the Swedish NICE-cohort
Associations of the placental metabolome with immune maturation up to one year of age in the Swedish NICE-cohort Open
Introduction: Allergies and other immune-mediated diseases are thought to result from incomplete maturation of the immune system early in life. We previously showed that infants’ metabolites at birth were associated with immune cell subtyp…
View article: Mediation by Thyroid Hormone in the Relationships Between Gestational Exposure to Methylmercury and Birth Size
Mediation by Thyroid Hormone in the Relationships Between Gestational Exposure to Methylmercury and Birth Size Open
Our previous studies have linked gestational methylmercury exposure, originating from seafood, to changes in maternal thyroid hormones and infant birth size in a Swedish birth cohort. Herein we aimed to determine associations between mater…
View article: Identification of metabotypes in complex biological data using tensor decomposition
Identification of metabotypes in complex biological data using tensor decomposition Open
Differences in the physiological response to treatment, such as dietary intervention, has led to the development of precision approaches in nutrition and medicine to tailor treatment for improved benefits to the individual. One such approa…
View article: Nutritional Composition and Estimated Iron and Zinc Bioavailability of Meat Substitutes Available on the Swedish Market
Nutritional Composition and Estimated Iron and Zinc Bioavailability of Meat Substitutes Available on the Swedish Market Open
Transition towards plant-based diets is advocated to reduce the climate footprint. Health implications of a diet composed of meat substitutes are currently unknown, and there are knowledge gaps in their nutritional composition and quality.…
View article: Association of maternal fluoride exposure during pregnancy with increased size at birth and the potential mediation effect by maternal thyroid hormones: the Swedish NICE birth cohort
Association of maternal fluoride exposure during pregnancy with increased size at birth and the potential mediation effect by maternal thyroid hormones: the Swedish NICE birth cohort Open
BACKGROUND AND AIM: Observational studies have indicated that maternal fluoride exposure during gestation may impair child neurodevelopment but a potential impact on birth outcomes is understudied. The aim of the study is to evaluate the i…
View article: Association of maternal urinary fluoride concentrations during pregnancy with size at birth and the potential mediation effect by maternal thyroid hormones: The Swedish NICE birth cohort
Association of maternal urinary fluoride concentrations during pregnancy with size at birth and the potential mediation effect by maternal thyroid hormones: The Swedish NICE birth cohort Open
Gestational urinary fluoride concentrations were associated with increased size at birth and even with increased odds of being born large for gestational age. The fluoride-related associations with increased size at birth were not explaine…
View article: Lower Non-Heme Iron Absorption in Healthy Females from Single Meals with Texturized Fava Bean Protein Compared to Beef and Cod Protein Meals: Two Single-Blinded Randomized Trials
Lower Non-Heme Iron Absorption in Healthy Females from Single Meals with Texturized Fava Bean Protein Compared to Beef and Cod Protein Meals: Two Single-Blinded Randomized Trials Open
Meat analogs based on plant protein extracts are rising in popularity as meat consumption declines. A dietary shift away from meat, which has a high iron bioavailability, may have a negative effect on the amount of iron absorbed from the d…
View article: Pilot-Scale Protein Recovery from Cold-Pressed Rapeseed Press Cake: Influence of Solids Recirculation
Pilot-Scale Protein Recovery from Cold-Pressed Rapeseed Press Cake: Influence of Solids Recirculation Open
The agricultural sector is responsible for about 30% of greenhouse gas emissions, and thus there is a need to develop new plant-based proteins with lower climate impact. Rapeseed press cake, a by-product from rapeseed oil production, conta…
View article: Differences between Arterial and Venous Umbilical Cord Plasma Metabolome and Association with Parity
Differences between Arterial and Venous Umbilical Cord Plasma Metabolome and Association with Parity Open
Umbilical cord blood is frequently used in health monitoring of the neonate. Results may be affected by the proportion of arterial and venous cord blood, the venous blood coming from the mother to supply oxygen and nutrients to the infant,…
View article: Maternal characteristics and pregnancy outcomes in the NICE birth cohort: an assessment of self-selection bias
Maternal characteristics and pregnancy outcomes in the NICE birth cohort: an assessment of self-selection bias Open
Self-selection to the NICE study was evident in some factors related to lifestyle and socioeconomic characteristics but did not appear to skew pregnancy outcomes or alter well-known effects of certain lifestyle parameters on pregnancy outc…
View article: Protein extraction from cold‐pressed hempseed press cake: From laboratory to pilot scale
Protein extraction from cold‐pressed hempseed press cake: From laboratory to pilot scale Open
During the production of industrial hempseed oil, a press cake is formed as a byproduct, which is often used as animal feed although it contains a high amount of protein that could be used for human consumption. Extracting this valuable pr…
View article: Infant Iodine and Selenium Status in Relation to Maternal Status and Diet During Pregnancy and Lactation
Infant Iodine and Selenium Status in Relation to Maternal Status and Diet During Pregnancy and Lactation Open
Iodine and selenium are essential trace elements. Recent studies indicate that pregnant and lactating women often have insufficient intake of iodine and selenium, but the impact on fetal and infant status is unclear. Here, we assessed iodi…