J. Scott Arn
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Prolonged Skin Graft Survival and Histocompatibility in Highly Inbred Miniature Swine Open
Background. Pigs are potential organ donors for humans. Some proposed xenotransplant tolerance regimens require genetically identical cells from different animals (eg, juvenile bone marrow and mature organs or tissues). We therefore sought…
View article: Antibody reactivity with new antigens revealed in multi‐transgenic triple knockout pigs may cause early loss of pig kidneys in baboons
Antibody reactivity with new antigens revealed in multi‐transgenic triple knockout pigs may cause early loss of pig kidneys in baboons Open
Background Recent advances in gene editing technology have enabled the production of multi‐knockout (KO) and transgenic pigs in order to overcome immunologic barriers in xenotransplantation (XTx). However, the genetic manipulations require…