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View article: Maresin-1 and S-Equol as Emerging Metabolic Biomarkers in Gestational Diabetes-Associated Inflammation
Maresin-1 and S-Equol as Emerging Metabolic Biomarkers in Gestational Diabetes-Associated Inflammation Open
Background/Objectives: The most prevalent metabolic condition during pregnancy is gestational diabetes mellitus (GDM), typically diagnosed in the second or third trimester and absent prior to gestation, with a reported prevalence ranging b…
View article: A direct association between suicide and reduced amygdala volume: A retrospective study
A direct association between suicide and reduced amygdala volume: A retrospective study Open
Objective The neurological causes of suicide remain poorly understood. This study sought to ascertain whether there is a correlation between amygdala volume and suicidal behavior. Methods This case–control retrospective study included 193 …
View article: An Important Biomarker in Patients with Bell’s Palsy: Serum Calprotectin
An Important Biomarker in Patients with Bell’s Palsy: Serum Calprotectin Open
Background and Objectives: This study aimed to examine the relationship between serum calprotectin levels and facial paralysis in patients with Bell’s palsy and to determine its prognostic significance. Materials and Methods: This study in…
View article: The Determination of serum Adropın level according to concentration levels of HbA1c in patients wıth Type 2 Diabetes Mellitus
The Determination of serum Adropın level according to concentration levels of HbA1c in patients wıth Type 2 Diabetes Mellitus Open
Purpose: Adropin is discovered in recent years and it has been reported to be associated with glucose and lipid metabolism . Our aim is to determine the relationship between blood serum adropin levels according to blood glycosylated hemogl…
View article: Moderate/High-Intensity Exercise and Coenzyme Q10 Supplementation May Reduce Tumstatin and Improve the Lipid Dynamics and Body Mass in Rats
Moderate/High-Intensity Exercise and Coenzyme Q10 Supplementation May Reduce Tumstatin and Improve the Lipid Dynamics and Body Mass in Rats Open
Coenzyme Q10 (CoQ10) is a molecule that serves as a coenzyme for mitochondrial enzymes, playing a fundamental role in mitochondrial bioenergetics as an electron and proton carrier in the energy production process. This study aimed to exami…
View article: The Regulatory Effects of Exercise and Metformin on Biomarkers in Obesity: A Focus on Uric Acid, Irisin, Adiponutrin, Adropin, and Copeptin
The Regulatory Effects of Exercise and Metformin on Biomarkers in Obesity: A Focus on Uric Acid, Irisin, Adiponutrin, Adropin, and Copeptin Open
Background and Objectives: Obesity has become one of the most significant health problems nowadays, with its prevalence rapidly increasing. Approaches such as diet and exercise play an important role in the treatment of obesity. This study…
View article: An overview of ELISA: a review and update on best laboratory practices for quantifying peptides and proteins in biological fluids
An overview of ELISA: a review and update on best laboratory practices for quantifying peptides and proteins in biological fluids Open
The enzyme-linked immunosorbent assay (ELISA) detects antigen-antibody interactions by using enzyme-labelled conjugates and enzyme substrates that generate colour changes. This review aims to provide an overview of ELISA, its various types…
View article: Tear and blood salusin-α, and -β, copeptin, and asprosin in patients with glaucoma and ocular hypertension
Tear and blood salusin-α, and -β, copeptin, and asprosin in patients with glaucoma and ocular hypertension Open
Fluids from patients with open-angle glaucoma and ocular hypertension showed lower salusin levels. Patients with ocular hypertension had higher levels of copeptin and asprosin, but not those with open-angle glaucoma (except for asprosin, w…
View article: Serum and urine adropin levels following urinary microalbuminuria in patients with type 2 diabetes
Serum and urine adropin levels following urinary microalbuminuria in patients with type 2 diabetes Open
Objective: Diabetes mellitus disrupts energy balance due to insulin deficiency or resistance, presenting a significant public health challenge. A major complication is end-stage renal disease (ESRD), primarily resulting from diabetic nephr…
View article: Trimethylamine N-oxide, S-equol, and indoxyl sulfate inflammatory microbiota players in ocular Behçet’s disease
Trimethylamine N-oxide, S-equol, and indoxyl sulfate inflammatory microbiota players in ocular Behçet’s disease Open
Objectives The aims of the study were to assess the levels of serum TMAO, S-equol, and indoxyl sulfate in subjects with ocular active Behçet’s disease (OABD) and ocular inactive Behçet’s disease (OIBD). Methods The study involved 22 patien…
View article: Some animal protein antigens identified in cells of two plant species
Some animal protein antigens identified in cells of two plant species Open
Objectives It has been recently reported that immune activity of some animal peptides/proteins has been found in some plants. In this study, the presence of immune reactivity of alarin, asprosin, paraoxonase, elabela, glucagon, and nesfati…
View article: Leptin, Ghrelin, Irisin, Asprosin and Subfatin Changes in Obese Women: Effect of Exercise and Different Nutrition Types
Leptin, Ghrelin, Irisin, Asprosin and Subfatin Changes in Obese Women: Effect of Exercise and Different Nutrition Types Open
Background and Objectives: In this study, the effects of a six-week training program and various diets on subfatin, asprosin, irisin, leptin, ghrelin and the lipid profile were investigated in overweight women. Materials and Methods: A tot…
View article: Investigation of Trpa1 and Trpc1 Immunreactivities in Colon Adenocarcinomas
Investigation of Trpa1 and Trpc1 Immunreactivities in Colon Adenocarcinomas Open
TRPA1 and TRPC1 immunoreactivites are increased in colorectal adenocarcinoma tissue compared with the healthy tissue. Furthermore, the immunoreactivity decreases as the grade of cancer increases.
View article: Investigation of the role of Irisin and FABP4 in iron deficiency anemia
Investigation of the role of Irisin and FABP4 in iron deficiency anemia Open
Purpose Anemia is defined as a condition in which the level of Hemoglobin is lower than the expected level based on age and gender.Irisin (Ir) was discovered in 2012 to be a muscle-associated factor.Fatty acid binding proteins (FABPs) are …
View article: Investigation of the Effects of Silymarin and Vitamin C on Kidney Damage and Aquaporin-2 Downregulation in Lithium-Induced Nephrogenic Diabetes Insipidus in Rats
Investigation of the Effects of Silymarin and Vitamin C on Kidney Damage and Aquaporin-2 Downregulation in Lithium-Induced Nephrogenic Diabetes Insipidus in Rats Open
While lithium (LIT) therapy is widely regarded as the primary approach for managing bipolar disorder over the long term, it is also a major contributor to the development of acquired Nephrogenic Diabetes Insipidus (NDI) with prolonged use.…
View article: Relationships between Anxiety, Depression, and Illness Perceptions in Lung and Breast Cancer Patients throughout the Cancer Continuum
Relationships between Anxiety, Depression, and Illness Perceptions in Lung and Breast Cancer Patients throughout the Cancer Continuum Open
Cancer is a devastating disease that has significant psychological and biological impacts. Generally, lung cancer primarily affects men while breast cancer primarily affects women. Thus, this study aimed to investigate the levels of anxiet…
View article: Inflammation Markers in Patients with Bipolar Disorder Who Have Committed Offenses and Their Relationship with Criminal Behavior
Inflammation Markers in Patients with Bipolar Disorder Who Have Committed Offenses and Their Relationship with Criminal Behavior Open
Background and Objectives: This study aimed to examine the function of various inflammation parameters and their interactions in the pathology of Bipolar disorder (BD) and to assess whether they could be biomarkers in the relationship betw…
View article: Plasma and aqueous levels of subfatin, preptin and betatrophin in patients with diabetic retinopathy
Plasma and aqueous levels of subfatin, preptin and betatrophin in patients with diabetic retinopathy Open
Aim To examine subfatin, preptin and betatrophin levels in plasma and aqueous in patients with diabetes mellitus (DM) (with and without retinopathy). Material and method Sixty patients, who were similar in terms of age and gender, and were…
View article: THE RELATIONSHIP OF BODY MASS INDEX WITH SERUM TGF-BETA LEVEL AND CLINICAL FINDINGS IN PATIENTS WITH SYSTEMIC SCLEROSIS
THE RELATIONSHIP OF BODY MASS INDEX WITH SERUM TGF-BETA LEVEL AND CLINICAL FINDINGS IN PATIENTS WITH SYSTEMIC SCLEROSIS Open
Aim: Aim: Systemic sclerosis (SSc) is an inflammatory disease characterized by a widespread fibrosis of affected tissue.Obesity is characterized as a chronic inflammatory state and affects the production of cytokines.The aim of the present…
View article: Levels of Serum and Urine Catecholaminergic and Apelinergic System Members in Acute Ischemic Stroke Patients
Levels of Serum and Urine Catecholaminergic and Apelinergic System Members in Acute Ischemic Stroke Patients Open
Objective: To compare levels of catecholaminergic system members, renalase, cerebellin, and their substrates, epinephrine, norepinephrine, and dopamine, and apelinergic system members, apelin, elabela, and nitric oxide in the blood and uri…
View article: Effects of Iron Deficiency Anemia and its Treatment on Ghrelins, Obestatin and Heat Shock Protein 70
Effects of Iron Deficiency Anemia and its Treatment on Ghrelins, Obestatin and Heat Shock Protein 70 Open
The impact of iron deficiency anemia (IDA) and its treatment on increased levels of heat shock protein 70 (HSP70) in settings with higher tissue stress induced by both ghrelin, which is both an antioxidant and a food intake stimulant, and …
View article: Serum asprosin levels in patients with retinopathy of prematurity
Serum asprosin levels in patients with retinopathy of prematurity Open
Objectives This study was aimed to investigate the diagnostic values of serum levels of asprosin and neutrophil gelatinase-associated lipocalin (NGAL) in Retinopathy of prematurity (ROP) and to assess the role of these biomarkers on the de…
View article: Plasma and aqueous levels of alarin and adipsin in patients with and without diabetic retinopathy
Plasma and aqueous levels of alarin and adipsin in patients with and without diabetic retinopathy Open
Backround Diabetic retinopathy is a disease seen with microvascular complications as a result of hyperglycemia and insulin resistance. Alarin and Adipsin are molecules with a role in energy and glucose metabolism. The aim of this study was…
View article: Blood, saliva and urine maresin-1 and malondialdehyde may be useful biomarker in patients with polycystic ovary syndrome: a prospective study
Blood, saliva and urine maresin-1 and malondialdehyde may be useful biomarker in patients with polycystic ovary syndrome: a prospective study Open
Background: Maresin-1 (MaR1) plays a major role in many inflammatory disorders. Polycystic ovary syndrome (PCOS) aside from a hormonal disorder, an inflammation might also contribute to PCOS and its metabolic associations. Therefore, the p…
View article: Plasma and aqueous humor levels of adiponutrin and pannexin 1 in patients with and without diabetic retinopathy
Plasma and aqueous humor levels of adiponutrin and pannexin 1 in patients with and without diabetic retinopathy Open
AIM: To evaluate plasma and aqueous levels of adiponutrin and pannexin 1 in patients with and without diabetic retinopathy. METHODS: The study included three age and gender-matched groups of 20 cataract patients with no diabetes or additio…
View article: Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome
Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome Open
Although there is not yet full clarity of the pathogenesis of fibromyalgia syndrome (FM), central sensitization is considered to be responsible. The purpose of this study was to measure the plasma levels of potassium ion channel proteins (…
View article: Plasma And Aqueous Levels Of Alarin And Adipsin In Patients With and Without Diabetic Retinopathy
Plasma And Aqueous Levels Of Alarin And Adipsin In Patients With and Without Diabetic Retinopathy Open
Backround: Diabetic retinopathy is a disease seen with microvascular complications as a result of hyperglycemia and insulin resistance. Alarin and Adipsin are molecules with a role in energy and glucose metabolism. The aim of this study wa…
View article: Severe Acute Respiratory Syndrome -Possible Sources of Error in Diagnosis and their Validity in the Coronavirus Disease Series
Severe Acute Respiratory Syndrome -Possible Sources of Error in Diagnosis and their Validity in the Coronavirus Disease Series Open
Viral diseases (recently monkeypox viral disease) are very common in our era and some viruses such as SARS-CoV-2 threaten humanity by causing a severe acute respiratory syndrome.This disease has been linked to haematological dysfunctions.S…