Evan Bardot
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View article: Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis
Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis Open
View article: Highly multiplexed spatially resolved gene expression profiling of mouse organogenesis
Highly multiplexed spatially resolved gene expression profiling of mouse organogenesis Open
Transcriptional and epigenetic profiling of single-cells has advanced our knowledge of the molecular bases of gastrulation and early organogenesis. However, current approaches rely on dissociating cells from tissues, thereby losing the cru…
View article: Mouse gastrulation: Coordination of tissue patterning, specification and diversification of cell fate
Mouse gastrulation: Coordination of tissue patterning, specification and diversification of cell fate Open
View article: Notch Signaling Commits Mesoderm to the Cardiac Lineage
Notch Signaling Commits Mesoderm to the Cardiac Lineage Open
During development multiple progenitor populations contribute to the formation of the four-chambered heart and its diverse lineages. However, the underlying mechanisms that result in the specification of these progenitor populations are no…
View article: A Watershed Finding for Heart Regeneration
A Watershed Finding for Heart Regeneration Open
View article: Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential
Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential Open
View article: Probing early heart development to instruct stem cell differentiation strategies
Probing early heart development to instruct stem cell differentiation strategies Open
Scientists have studied organs and their development for centuries and, along that path, described models and mechanisms explaining the developmental principles of organogenesis. In particular, with respect to the heart, new fundamental di…
View article: RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins
RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins Open
The sea urchin larval skeleton offers a simple model for developmental pattern formation. The calcium carbonate skeleton is secreted by primary mesenchyme cells (PMCs) in response to largely unknown patterning cues expressed by the ectoder…