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View article: [Translated article] Physicochemical and microbiological stability study of two new preservative-free methylprednisolone eye drops
[Translated article] Physicochemical and microbiological stability study of two new preservative-free methylprednisolone eye drops Open
1 mg/mL MTPSS eye drops show physicochemical and microbiological stability for 21 days under refrigeration, compared to 42 days for 10 mg/mL eye drops stored under the same conditions. However, since they do not include preservatives in th…
View article: A Simple, Safe, and Effective Method for Preparing Autologous Bio-Based Fibrin Glue for Ophthalmic Use
A Simple, Safe, and Effective Method for Preparing Autologous Bio-Based Fibrin Glue for Ophthalmic Use Open
This study proposes a method to prepare autologous bio-based fibrin glue (FG) for use in ophthalmic surgery. FGs containing three fibrinogen concentrations and a thrombin concentrate were prepared using human blood from five donors (FG1: p…
View article: Mini Cleanroom for the Manufacture of Advanced Therapy Medicinal Products (ATMP): Bioengineered Corneal Epithelium
Mini Cleanroom for the Manufacture of Advanced Therapy Medicinal Products (ATMP): Bioengineered Corneal Epithelium Open
Among several requirements for the manufacture of Advanced Therapy Medicinal Products (ATMP) are: following the guidelines of a pharmaceutical quality system, complying with Good Manufacturing Practice (GMP) and access to a cleanroom fulfi…
View article: Fibrin-Plasma Rich in Growth Factors Membrane for the Treatment of a Rabbit Alkali-Burn Lesion
Fibrin-Plasma Rich in Growth Factors Membrane for the Treatment of a Rabbit Alkali-Burn Lesion Open
The purpose of this work is to describe the use of Fibrin-Plasma Rich in Growth Factors (PRGF) membranes for the treatment of a rabbit alkali-burn lesion. For this purpose, an alkali-burn lesion was induced in 15 rabbits. A week later, cli…
View article: Hospital Pharmacy Compounding against COVID-19 pandemic.
Hospital Pharmacy Compounding against COVID-19 pandemic. Open
As in other areas of the health system, COVID-19 has had a dramatic impact on hospital compounding. This area has faced numerous challenges, including the shortage of frequent-use products (hydroalcoholic solutions, lopinavir/ritonavir sus…
View article: 3PC-032 Autologous tissue adhesive in ophthalmological surgery
3PC-032 Autologous tissue adhesive in ophthalmological surgery Open
Background and importance Sutures to replace tissue adhesives have enhanced importance. However, commercialised drugs are allogenic, synthetic and expensive, increasing surgery costs. Aim and objectives To produce an autologous tissue adhe…
View article: 3PC-010 Stability of chlorhexidine 0.05% eye drops compounding drug
3PC-010 Stability of chlorhexidine 0.05% eye drops compounding drug Open
Background Chlorhexidine has been used as a surgical prophylaxis in patients allergic to povidone in order to reduce post-surgery infections.1 Purpose To develop a 0.05% chlorhexidine ophthalmic formulation and study its stability in diffe…
View article: Plasma rich in growth factors membrane as coadjuvant treatment in the surgery of ocular surface disorders
Plasma rich in growth factors membrane as coadjuvant treatment in the surgery of ocular surface disorders Open
To evaluate the safety and efficacy of the surgical use of plasma rich in growth factors fibrin membrane (mPRGF) in different ocular surface pathologies.Fifteen patients with different corneal and conjunctival diseases were included in the…
View article: Topical Tacrolimus for Corneal Subepithelial Infiltrates Secondary to Adenoviral Keratoconjunctivitis
Topical Tacrolimus for Corneal Subepithelial Infiltrates Secondary to Adenoviral Keratoconjunctivitis Open
Purpose: The objective of this study was to determine the efficacy and safety of topical tacrolimus compounded in the Pharmacy Service for the treatment of subepithelial corneal infiltrates (SEIs) secondary to adenoviral keratoconjunctivit…