Stefan Blüml
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View article: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research
The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research Open
Covering: up to 2018With contributions from the global natural product (NP) research community, and continuing the Raw Data Initiative, this review collects a comprehensive demonstration of the immense scientific value of disseminating raw…
View article: Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research
Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research Open
Correction for 'The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research'
View article: POS1425 MEDIATORS OF OSTEOPETROSIS IN miR-146a DEFICIENT MICE
POS1425 MEDIATORS OF OSTEOPETROSIS IN miR-146a DEFICIENT MICE Open
View article: PATH-06. AN INTEGRATIVE MULTI-MODAL DIAGNOSTIC APPROACH TO PEDIATRIC CHOROID PLEXUS TUMORS
PATH-06. AN INTEGRATIVE MULTI-MODAL DIAGNOSTIC APPROACH TO PEDIATRIC CHOROID PLEXUS TUMORS Open
BACKGROUND Choroid plexus tumors (CPTs) consist of a diverse group of neoplasms, more prevalent in children. They include choroid plexus papillomas (CPPs, grade 1), atypical choroid plexus papillomas (aCPPs, grade 2), and choroid plexus ca…
View article: Corrigendum to: Glutathione Increase and Seizure Burden Decrease in Patients with Intractable Epilepsy on Ketogenic Diet
Corrigendum to: Glutathione Increase and Seizure Burden Decrease in Patients with Intractable Epilepsy on Ketogenic Diet Open
[This corrects the article DOI: 10.14581/jer.23001.].
View article: Brain Injury Outcomes after Adjuvant Erythropoietin Neuroprotection for Moderate or Severe Neonatal Hypoxic-Ischemic Encephalopathy: A Report from the HEAL Trial
Brain Injury Outcomes after Adjuvant Erythropoietin Neuroprotection for Moderate or Severe Neonatal Hypoxic-Ischemic Encephalopathy: A Report from the HEAL Trial Open
Introduction: Erythropoietin (Epo) is a putative neuroprotective therapy that did not improve overall outcomes in a phase 3 randomized controlled trial for neonates with moderate or severe hypoxic-ischemic encephalopathy (HIE). However, HI…
View article: Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus
Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus Open
OBJECTIVE Standard MRI protocols lack a quantitative sequence that can be used to evaluate shunt-treated patients with a history of hydrocephalus. The objective of this study was to investigate the use of phase-contrast MRI (PC-MRI), a qua…
View article: Altered In Utero Metabolic Brain Trajectories in CHD
Altered In Utero Metabolic Brain Trajectories in CHD Open
View article: Assessment of Brain Magnetic Resonance and Spectroscopy Imaging Findings and Outcomes After Pediatric Cardiac Arrest
Assessment of Brain Magnetic Resonance and Spectroscopy Imaging Findings and Outcomes After Pediatric Cardiac Arrest Open
Importance Morbidity and mortality after pediatric cardiac arrest are chiefly due to hypoxic-ischemic brain injury. Brain features seen on magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) after arrest may identify…
View article: Brain Glutathione Increase and Seizure Burden Decrease in Patients with Intractable Epilepsy on Ketogenic Diet
Brain Glutathione Increase and Seizure Burden Decrease in Patients with Intractable Epilepsy on Ketogenic Diet Open
Background and Purpose: Ketogenic diet (KD) improves seizure control in patients with drug-resistant epilepsy. As increased mitochondrial levels of glutathione (GSH) might contribute to a change in seizure susceptibility, we quantified cha…
View article: How well does neonatal neuroimaging correlate with neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy?
How well does neonatal neuroimaging correlate with neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy? Open
Background In newborns with hypoxic-ischemic encephalopathy (HIE), the correlation between neonatal neuroimaging and the degree of neurodevelopmental impairment (NDI) is unclear. Methods Infants with HIE enrolled in a randomized controlled…
View article: Supplementary Material for: Brain Injury Outcomes after Adjuvant Erythropoietin Neuroprotection for Moderate or Severe Neonatal Hypoxic-Ischemic Encephalopathy: A Report from the HEAL Trial
Supplementary Material for: Brain Injury Outcomes after Adjuvant Erythropoietin Neuroprotection for Moderate or Severe Neonatal Hypoxic-Ischemic Encephalopathy: A Report from the HEAL Trial Open
Introduction. Erythropoietin (Epo) is a putative neuroprotective therapy that did not improve overall outcomes in a phase 3 randomized controlled trial for neonates with moderate or severe hypoxic-ischemic encephalopathy (HIE). However, HI…
View article: Reviewer Lists
Reviewer Lists Open
Journal Article Reviewer Lists Get access Neuro-Oncology, Volume 25, Issue 1, January 2023, Pages 214–216, https://doi.org/10.1093/neuonc/noac277 Published: 05 January 2023 Article history Corrected and typeset: 05 January 2023 Published: …
View article: Supplementary Material for: Brain Injury Outcomes after Adjuvant Erythropoietin Neuroprotection for Moderate or Severe Neonatal Hypoxic-Ischemic Encephalopathy: A Report from the HEAL Trial
Supplementary Material for: Brain Injury Outcomes after Adjuvant Erythropoietin Neuroprotection for Moderate or Severe Neonatal Hypoxic-Ischemic Encephalopathy: A Report from the HEAL Trial Open
Introduction. Erythropoietin (Epo) is a putative neuroprotective therapy that did not improve overall outcomes in a phase 3 randomized controlled trial for neonates with moderate or severe hypoxic-ischemic encephalopathy (HIE). However, HI…
View article: Magnetic Resonance Spectroscopy Metabolites as Biomarkers of Disease Status in Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG) Treated with Glioma-Associated Antigen Peptide Vaccines
Magnetic Resonance Spectroscopy Metabolites as Biomarkers of Disease Status in Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG) Treated with Glioma-Associated Antigen Peptide Vaccines Open
Purpose: Diffuse intrinsic pontine gliomas (DIPG) are highly aggressive tumors with no currently available curative therapy. This study evaluated whether measurements of in vivo cell metabolites using magnetic resonance spectroscopy (MRS) …
View article: Quantitative Susceptibility Mapping: Translating an Investigative Research Tool into High Volume Clinical Diagnostic Imaging
Quantitative Susceptibility Mapping: Translating an Investigative Research Tool into High Volume Clinical Diagnostic Imaging Open
Quantitative susceptibility mapping (QSM) is an MRI-based technique for iron quantification of targeted tissue. QSM provides information relevant to clinicians in a broad range of diagnostic contexts, including sickle cell disease, inflamm…
View article: Association of Blood-Based Brain Injury Biomarker Concentrations With Outcomes After Pediatric Cardiac Arrest
Association of Blood-Based Brain Injury Biomarker Concentrations With Outcomes After Pediatric Cardiac Arrest Open
In this cohort study, blood-based brain injury biomarkers, especially NfL, were associated with an unfavorable outcome at 1 year after pediatric cardiac arrest. Additional evaluation of the accuracy of the association between biomarkers an…
View article: Trial of Erythropoietin for Hypoxic–Ischemic Encephalopathy in Newborns
Trial of Erythropoietin for Hypoxic–Ischemic Encephalopathy in Newborns Open
The administration of erythropoietin to newborns undergoing therapeutic hypothermia for hypoxic-ischemic encephalopathy did not result in a lower risk of death or neurodevelopmental impairment than placebo and was associated with a higher …
View article: Use of Magnetic Resonance Imaging in Neuroprognostication After Pediatric Cardiac Arrest: Survey of Current Practices
Use of Magnetic Resonance Imaging in Neuroprognostication After Pediatric Cardiac Arrest: Survey of Current Practices Open
View article: Proton MR Spectroscopy of Pediatric Brain Disorders
Proton MR Spectroscopy of Pediatric Brain Disorders Open
In vivo MR spectroscopy is a non -invasive methodology that provides information about the biochemistry of tissues. It is available as a “push-button” application on state-of-the-art clinical MR scanners. MR spectroscopy has been used to s…
View article: Brain Glutathione Increase and Seizure Burden Decrease in Patients with Intractable Epilepsy on Ketogenic Diet
Brain Glutathione Increase and Seizure Burden Decrease in Patients with Intractable Epilepsy on Ketogenic Diet Open
Background and Purpose : Ketogenic diet (KD) improves seizure control in patients with drug-resistant forms of epilepsy; however, the mechanism of action remains poorly understood. Increased mitochondrial levels of glutathione (GSH) might …
View article: The First Examination of Diagnostic Performance of Automated Measurement of the Callosal Angle in 1856 Elderly Patients and Volunteers Indicates That 12.4% of Exams Met the Criteria for Possible Normal Pressure Hydrocephalus
The First Examination of Diagnostic Performance of Automated Measurement of the Callosal Angle in 1856 Elderly Patients and Volunteers Indicates That 12.4% of Exams Met the Criteria for Possible Normal Pressure Hydrocephalus Open
In even the most pristine research databases, analyses of the callosal angle indicate that some patients may have normal pressure hydrocephalus. The automatic callosal angle measurement can rapidly and objectively screen for normal pressur…
View article: Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas Open
Childhood posterior fossa group A ependymomas demonstrate integrated metabolic and epigenetic pathways that can be disrupted by metformin.
View article: Algorithms for segmenting cerebral time-of-flight magnetic resonance angiograms from volunteers and anemic patients
Algorithms for segmenting cerebral time-of-flight magnetic resonance angiograms from volunteers and anemic patients Open
Purpose: To evaluate six cerebral arterial segmentation algorithms in a set of patients with a wide range of hemodynamic characteristics to determine real-world performance. Approach: Time-of-flight magnetic resonance angiogr…
View article: Integrating neuroimaging biomarkers into the multicentre, high-dose erythropoietin for asphyxia and encephalopathy (HEAL) trial: rationale, protocol and harmonisation
Integrating neuroimaging biomarkers into the multicentre, high-dose erythropoietin for asphyxia and encephalopathy (HEAL) trial: rationale, protocol and harmonisation Open
Introduction MRI and MR spectroscopy (MRS) provide early biomarkers of brain injury and treatment response in neonates with hypoxic-ischaemic encephalopathy). Still, there are challenges to incorporating neuroimaging biomarkers into multis…
View article: Elevated Citrate Levels and Histone H3K27M mutations in Pediatric Midline Gliomas-Predictors of Adverse Outcome
Elevated Citrate Levels and Histone H3K27M mutations in Pediatric Midline Gliomas-Predictors of Adverse Outcome Open
Background: Low Grade Gliomas(LGG) account for about 50% of childhood brain tumors. Elevated citrate levels have previously been shown to be markers for aggressive behavior in LGGs and the H3K27M and G34R/V mutations have emerged as molecu…
View article: Fetal neurodevelopmental recovery in donors after laser surgery for twin‐twin transfusion syndrome
Fetal neurodevelopmental recovery in donors after laser surgery for twin‐twin transfusion syndrome Open
Background Fetal magnetic resonance imaging (MRI) and spectroscopy (MRS) provide a unique opportunity to non‐invasively measure markers of neurodevelopment in survivors of twin‐twin transfusion syndrome (TTTS). Objective To characterize fe…
View article: Personalising Outcomes after Child Cardiac Arrest (POCCA): design and recruitment challenges of a multicentre, observational study
Personalising Outcomes after Child Cardiac Arrest (POCCA): design and recruitment challenges of a multicentre, observational study Open
Introduction Blood and imaging biomarkers show promise in prognosticating outcomes after paediatric cardiac arrest in pilot studies. We describe the methods and early recruitment challenges and solutions for an ongoing multicentre (n=14) o…
View article: Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas Open
View article: Brain MR imaging and spectroscopy for outcome prognostication after pediatric cardiac arrest
Brain MR imaging and spectroscopy for outcome prognostication after pediatric cardiac arrest Open