Paula Bourke
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View article: Biomedical Application of Cold Plasma: Navigating Through Plasma Types and Devices by Antimicrobial Effectiveness and Tissue Tolerance
Biomedical Application of Cold Plasma: Navigating Through Plasma Types and Devices by Antimicrobial Effectiveness and Tissue Tolerance Open
This study compares the biofilm efficacy and tissue compatibility of three cold atmospheric plasma devices: J‐Plasma (Apyx Medical), Piezo Brush PZ3 (Reylon Plasma GmbH), and Plasma Care (Terraplasma‐Medical GmbH). The focus is on surface …
View article: Enhanced Cytotoxic Effects of Cold Plasma Deposition of Topotecan: A Novel Approach for Local Cancer Drug Delivery to Glioblastoma Cells
Enhanced Cytotoxic Effects of Cold Plasma Deposition of Topotecan: A Novel Approach for Local Cancer Drug Delivery to Glioblastoma Cells Open
Background/Objectives: Despite the numerous advances in glioblastoma multiforme (GBM) treatment, GBM remains as the most malignant and aggressive form of brain cancer, characterized by a very poor outcome, highlighting the ongoing need for…
View article: Plasma activated water pre-treatment substantially enhances phage activity against Proteus mirabilis biofilms
Plasma activated water pre-treatment substantially enhances phage activity against Proteus mirabilis biofilms Open
The ongoing antimicrobial resistance crisis has incentivised research into alternative antibacterial and antibiofilm agents. One of them is plasma-activated water (PAW), which is produced by exposing water to a cold plasma discharge. This …
View article: Recent Developments in the Use of Plasma in Medical Applications
Recent Developments in the Use of Plasma in Medical Applications Open
A detailed review of the scientific literature was undertaken to examine the most recent developments in plasma processing in the field of medicine. The first part of the review includes a detailed breakdown of the different types of coati…
View article: Recent Developments in the use of Plasma for Therapeutic Applications
Recent Developments in the use of Plasma for Therapeutic Applications Open
A detailed review of the scientific literature was undertaken to examine the most recent developments in plasma processing in the field of medicine. The first part of the review includes a detailed breakdown of the different types of coati…
View article: Combined Effect of Plasma-Activated Water and Topotecan in Glioblastoma Cells
Combined Effect of Plasma-Activated Water and Topotecan in Glioblastoma Cells Open
The increase in cancer diagnoses and cancer deaths, severe side effects of existing treatments and resistance to traditional treatments have generated a need for new anticancer treatments. Glioblastoma multiforme (GBM) is the most common, …
View article: Cell death induced in glioblastoma cells by Plasma-Activated-Liquids (PAL) is primarily mediated by membrane lipid peroxidation and not ROS influx
Cell death induced in glioblastoma cells by Plasma-Activated-Liquids (PAL) is primarily mediated by membrane lipid peroxidation and not ROS influx Open
Since first identified in 1879, plasma, the fourth state of matter, has been developed and utilised in many fields. Nonthermal atmospheric plasma, also known as cold plasma, can be applied to liquids, where plasma reactive species such as …
View article: Emerging green cell disruption techniques to obtain valuable compounds from macro and microalgae: a review
Emerging green cell disruption techniques to obtain valuable compounds from macro and microalgae: a review Open
In the modern era, macro-microalgae attract a strong interest across scientific disciplines, owing to the wide application of these cost-effective valuable bioresources in food, fuel, nutraceuticals, and pharmaceuticals etc. The practice o…
View article: Cold plasma for insect pest control: <i>Tribolium castaneum</i> mortality and defense mechanisms in response to treatment
Cold plasma for insect pest control: <i>Tribolium castaneum</i> mortality and defense mechanisms in response to treatment Open
The insecticidal properties and mechanisms of high‐voltage air‐based atmospheric cold plasma using a contained dielectric barrier discharge reactor were investigated against Tribolium castaneum as an important bio‐contaminant in stored gra…
View article: Optimizing the application of plasma functionalised water (PFW) for microbial safety in fresh-cut endive processing
Optimizing the application of plasma functionalised water (PFW) for microbial safety in fresh-cut endive processing Open
The microbiological profiles and responses of native microflora of endive were investigated using a model process line, to establish where a defined PFW should be optimally applied to retain or improve produce microbiological quality. The …
View article: Combination of Natural Compounds With Novel Non-thermal Technologies for Poultry Products: A Review
Combination of Natural Compounds With Novel Non-thermal Technologies for Poultry Products: A Review Open
Ensuring safe, fresh, and healthy food across the shelf life of a commodity is an ongoing challenge, with the driver to minimize chemical additives and their residues in the food processing chain. High-value fresh protein products such as …
View article: Corrigendum: Biomolecules as Model Indicators of In Vitro and In Vivo Cold Plasma Safety
Corrigendum: Biomolecules as Model Indicators of In Vitro and In Vivo Cold Plasma Safety Open
In the original article, the reference for [16] was incorrectly written as “Khlyustova A, Jarzina F, Brinckmann S. Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: a brief review. Front Chem Sc…
View article: Characterization of an atmospheric pressure air plasma device under different modes of operation and their impact on the liquid chemistry
Characterization of an atmospheric pressure air plasma device under different modes of operation and their impact on the liquid chemistry Open
It has been shown that plasma generated in contact with liquid can be tailored to tune the composition of plasma functionalized liquids. For biomedical applications, it is necessary to understand the generation of the plasma treated liquid…
View article: Available technologies on improving the stability of polyphenols in food processing
Available technologies on improving the stability of polyphenols in food processing Open
Polyphenols are the most important phytochemicals in our diets and have received great attention due to their broad benefits for human health by suppressing oxidative stress and playing a protective role in preventing different pathologies…
View article: Distinct Chemistries Define the Diverse Biological Effects of Plasma Activated Water Generated with Spark and Glow Plasma Discharges
Distinct Chemistries Define the Diverse Biological Effects of Plasma Activated Water Generated with Spark and Glow Plasma Discharges Open
The spread of multidrug-resistant bacteria poses a significant threat to human health. Plasma activated liquids (PAL) could be a promising alternative for microbial decontamination, where different PAL can possess diverse antimicrobial eff…
View article: The Effect of Plasma Treated Water Unit Processes on the Food Quality Characteristics of Fresh-Cut Endive
The Effect of Plasma Treated Water Unit Processes on the Food Quality Characteristics of Fresh-Cut Endive Open
This study evaluated the impact of a defined plasma treated water (PTW) when applied to various stages within fresh-cut endive processing. The quality characteristic responses were investigated to establish the impact of the PTW unit proce…
View article: Biomolecules as Model Indicators of In Vitro and In Vivo Cold Plasma Safety
Biomolecules as Model Indicators of In Vitro and In Vivo Cold Plasma Safety Open
The potential applications for cold plasma in medicine are extensive, from microbial inactivation and induction of apoptosis in cancer cells to stimulating wound healing and enhancing the blood coagulation cascade. The safe bio-medical app…
View article: Novel decontamination approaches and their potential application for post-harvest aflatoxin control
Novel decontamination approaches and their potential application for post-harvest aflatoxin control Open
Background: Aflatoxin is considered to be the most important mycotoxin in the world for human food and animal feed. Current strategies for the reduction of mycotoxins in food and feed includes both prevention and removal. It is clear that …
View article: Temperature Stability and Effectiveness of Plasma-Activated Liquids over an 18 Months Period
Temperature Stability and Effectiveness of Plasma-Activated Liquids over an 18 Months Period Open
Non-buffered plasma-activated liquids such as water and saline have shown bactericidal effects. In the present study, we investigated the anti-bacterial efficacy and stability of plasma-activated water (PAW) and plasma-activated saline (PA…