Subhash C. Pandey
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View article: Impact of Social Media on Tourism Promotion: An Analytical Study on Uttarakhand
Impact of Social Media on Tourism Promotion: An Analytical Study on Uttarakhand Open
The utilisation of social media and other communication technologies contributes to the growth of the tourism business. Social media is the most potent internet medium, now an integral component of global social and economic life. Selwyn c…
View article: Advances in Sentiment and Emotion Analysis Techniques
Advances in Sentiment and Emotion Analysis Techniques Open
Introduction: Understanding and analyzing human emotions is a critical area of research, with applications spanning healthcare, education, entertainment, and human-computer interaction. Objective: Leveraging modalities such as facial expre…
View article: GANFIS: The Ensemble model for Affective Classification
GANFIS: The Ensemble model for Affective Classification Open
Emotions are a crucial aspect of daily life and play vital roles in human interactions as well as in different other domains such as entertainment, healthcare etc. Perhaps, the use of physiological signals can increase the clarity, objecti…
View article: EZH2-dependent epigenetic reprogramming in the central nucleus of amygdala regulates adult anxiety in both sexes after adolescent alcohol exposure
EZH2-dependent epigenetic reprogramming in the central nucleus of amygdala regulates adult anxiety in both sexes after adolescent alcohol exposure Open
View article: Surgical treatment of adolescent idiopathic scoliosis with a minimal invasive dynamic correction system -A preliminary report of A 24-month follow-up
Surgical treatment of adolescent idiopathic scoliosis with a minimal invasive dynamic correction system -A preliminary report of A 24-month follow-up Open
View article: Adolescent intermittent ethanol exposure alters adult exploratory and affective behaviors, and cerebellar Grin2b expression in C57BL/6J mice
Adolescent intermittent ethanol exposure alters adult exploratory and affective behaviors, and cerebellar Grin2b expression in C57BL/6J mice Open
View article: Transcriptional Dysregulation of Cholesterol Synthesis Underlies Hyposensitivity to GABA in the Ventral Tegmental Area During Acute Alcohol Withdrawal
Transcriptional Dysregulation of Cholesterol Synthesis Underlies Hyposensitivity to GABA in the Ventral Tegmental Area During Acute Alcohol Withdrawal Open
View article: ML based IoT Framework for Diabetes Detection
ML based IoT Framework for Diabetes Detection Open
There has been a discernible increase in the prevalence of diabetes in recent years, highlighting the significance of early detection in successfully managing the condition and avoiding complications. A chronic disease called diabetes is c…
View article: Conserved role for PCBP1 in altered RNA splicing in the hippocampus after chronic alcohol exposure
Conserved role for PCBP1 in altered RNA splicing in the hippocampus after chronic alcohol exposure Open
We previously discovered using transcriptomics that rats undergoing withdrawal after chronic ethanol exposure had increased expression of several genes encoding RNA splicing factors in the hippocampus. Here, we examined RNA splicing in the…
View article: Farmers’ Perception of Climate Change and Management Strategies in the Mid-Himalaya, India
Farmers’ Perception of Climate Change and Management Strategies in the Mid-Himalaya, India Open
View article: KCNK13 Potassium Channels are a Novel Target for Alcohol and Mediate the Activation of Ventral Tegmental Area Neurons
KCNK13 Potassium Channels are a Novel Target for Alcohol and Mediate the Activation of Ventral Tegmental Area Neurons Open
View article: Whole-Genome Approaches Identify Novel Epigenetic Networks in the Amygdala During Alcohol Dependence
Whole-Genome Approaches Identify Novel Epigenetic Networks in the Amygdala During Alcohol Dependence Open
View article: Advances in DNA, histone, and RNA methylation mechanisms in the pathophysiology of alcohol use disorder
Advances in DNA, histone, and RNA methylation mechanisms in the pathophysiology of alcohol use disorder Open
Alcohol use disorder (AUD) has a complex, multifactorial etiology involving dysregulation across several brain regions and peripheral organs. Acute and chronic alcohol consumption cause epigenetic modifications in these systems, which unde…
View article: Adolescent Intermittent Ethanol Exposure Alters Adult Exploratory and Affective Behaviors, and Cerebellar<i>Grin2B</i>Expression in C57BL/6J Mice
Adolescent Intermittent Ethanol Exposure Alters Adult Exploratory and Affective Behaviors, and Cerebellar<i>Grin2B</i>Expression in C57BL/6J Mice Open
Binge drinking is one of the most common patterns (more than 90%) of alcohol consumption by young people. During adolescence, the brain undergoes maturational changes that influence behavioral control and affective behaviors, such as cereb…
View article: Conserved role for PCBP1 in altered RNA splicing in the hippocampus after chronic alcohol exposure
Conserved role for PCBP1 in altered RNA splicing in the hippocampus after chronic alcohol exposure Open
We previously discovered using transcriptomics that rats undergoing withdrawal after chronic ethanol exposure had increased expression of several genes involved in RNA splicing in the hippocampus. Here, we examined RNA splicing in the rat …
View article: Neurosteroids (allopregnanolone) and alcohol use disorder: From mechanisms to potential pharmacotherapy
Neurosteroids (allopregnanolone) and alcohol use disorder: From mechanisms to potential pharmacotherapy Open
View article: Editorial: Adolescent brain and alcohol
Editorial: Adolescent brain and alcohol Open
EDITORIAL article Front. Pharmacol., 28 October 2022Sec. Neuropharmacology Volume 13 - 2022 | https://doi.org/10.3389/fphar.2022.1063446
View article: Unraveling the epigenomic and transcriptomic interplay during alcohol-induced anxiolysis
Unraveling the epigenomic and transcriptomic interplay during alcohol-induced anxiolysis Open
Positive effects of alcohol drinking such as anxiolysis and euphoria appear to be a crucial factor in the initiation and maintenance of alcohol use disorder (AUD). However, the mechanisms that lead from chromatin reorganization to transcri…
View article: Lifestyle modifications in the management of hypertensive patients in a Secondary Care Center: A Descriptive Cross-sectional Study
Lifestyle modifications in the management of hypertensive patients in a Secondary Care Center: A Descriptive Cross-sectional Study Open
Hypertension is the serious medical condition that significantly increases the risks of heart, brain, kidney and other diseases. This study evaluated the level of understanding of hypertensive patients regarding lifestyle modifications, th…
View article: Sickle Cell Anaemia among Tharu Population Visiting the Outpatient Department of General Medicine in a Secondary Care Centre: A Descriptive Cross-sectional Study
Sickle Cell Anaemia among Tharu Population Visiting the Outpatient Department of General Medicine in a Secondary Care Centre: A Descriptive Cross-sectional Study Open
Introduction: Sickle cell anaemia is a global health issue in which a mutation of the β-globin gene changes normal haemoglobin in sickle-shaped red blood cells. The objective of this study was to find out the prevalence of sickle cell anae…
View article: N6-methyladenosine (m6A) epitranscriptomics in synaptic plasticity and behaviors
N6-methyladenosine (m6A) epitranscriptomics in synaptic plasticity and behaviors Open
View article: Researching Mitigation of Alcohol Binge Drinking in Polydrug Abuse: KCNK13 and RASGRF2 Gene(s) Risk Polymorphisms Coupled with Genetic Addiction Risk Severity (GARS) Guiding Precision Pro-Dopamine Regulation
Researching Mitigation of Alcohol Binge Drinking in Polydrug Abuse: KCNK13 and RASGRF2 Gene(s) Risk Polymorphisms Coupled with Genetic Addiction Risk Severity (GARS) Guiding Precision Pro-Dopamine Regulation Open
Excessive alcohol intake, e.g., binge drinking, is a serious and mounting public health problem in the United States and throughout the world. Hence the need for novel insights into the underlying neurobiology that may help improve prevent…
View article: Acute and Protracted Prenatal Stress Produce Mood Disorder-Like and Ethanol Drinking Behaviors in Male and Female Adult Offspring
Acute and Protracted Prenatal Stress Produce Mood Disorder-Like and Ethanol Drinking Behaviors in Male and Female Adult Offspring Open
Background Alcohol use disorder (AUD) is a complex and chronic relapsing brain disease, which is often co-morbid with psychiatric disorders such as anxiety and depression. AUD phenotypes differ in men and women. Although genetic factors pl…
View article: Organophosphorus Poisoning among Acute Poisoning Cases Presenting to the Emergency Department of a Secondary Care Centre: A Descriptive Cross-sectional Study
Organophosphorus Poisoning among Acute Poisoning Cases Presenting to the Emergency Department of a Secondary Care Centre: A Descriptive Cross-sectional Study Open
Introduction: Organophosphorus is an easily available compound, especially in agriculture and farming related areas. This study evaluated organophosphorus poisoning among the population in those high-risk areas. The main objective of this …
View article: Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure
Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure Open
Adolescent binge drinking is a major risk factor for psychiatric disorders later in life including alcohol use disorder. Adolescent alcohol exposure induces epigenetic reprogramming at the enhancer region of the activity-regulated cytoskel…
View article: Chromosomes Identification Based Differential Evolution (CIDE): A New Bio-inspired Variant for Network Intrusion Detection
Chromosomes Identification Based Differential Evolution (CIDE): A New Bio-inspired Variant for Network Intrusion Detection Open
Chromosomes identification is of the paramount importance. The centromeric location of chromosomes is used to classify different species. Plethora of research has already been done in the domain of Bio-inspired computation. However, a Bio-…
View article: Emotion, Perception and Cognition: Psychological Analysis and Machine's Viability
Emotion, Perception and Cognition: Psychological Analysis and Machine's Viability Open
View article: Psycho-Philosophical Perspective of Intuition and its Machine Viability
Psycho-Philosophical Perspective of Intuition and its Machine Viability Open
View article: An operant ethanol self-administration paradigm that discriminates between appetitive and consummatory behaviors reveals distinct behavioral phenotypes in commonly used rat strains
An operant ethanol self-administration paradigm that discriminates between appetitive and consummatory behaviors reveals distinct behavioral phenotypes in commonly used rat strains Open
View article: Persistence of cerebellar ataxia during chronic ethanol exposure is associated with epigenetic up‐regulation of<i>Fmr1</i>gene expression in rat cerebellum
Persistence of cerebellar ataxia during chronic ethanol exposure is associated with epigenetic up‐regulation of<i>Fmr1</i>gene expression in rat cerebellum Open
Background Alcohol intoxication produces ataxia by affecting the cerebellum, which coordinates movements. Fragile X mental retardation (FMR) protein is a complex regulator of RNA and synaptic plasticity implicated in fragile X‐associated t…