Chirag Shah
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Impact of Pulmonary Rehabilitation on Quality-of-life Metrics in Patients with Chronic Respiratory Diseases: A Comparative Analysis of SF-36, SGRQ, and SOBQ Outcomes Open
Background Chronic respiratory diseases (CRDs) significantly impact patients’ quality-of-life (QoL), necessitating effective interventions for symptom management and functional improvement. Pulmonary rehabilitation (PR) has emerged as a po…
View article: Consensus recommendations regarding local and metastasis‐directed therapies in the management of relapsed/recurrent Ewing sarcoma
Consensus recommendations regarding local and metastasis‐directed therapies in the management of relapsed/recurrent Ewing sarcoma Open
Limited randomized or prospective data are available to guide local/metastasis directed therapy (LMDT) in relapsed/recurrent Ewing sarcoma (RR‐ES), resulting in uncertainty regarding best clinical practice for these patients. This report r…
Image-Guided Stereotactic Body Radiotherapy (SBRT) with Enhanced Visualization of Tumor and Hepatic Parenchyma in Patients with Primary and Metastatic Liver Malignancies Open
Goal: This study evaluates the feasibility and outcome of a personalized MRI-based liver SBRT treatment planning platform with the SPION contrast agent Ferumoxytol® (Sandoz Inc.; Princeton, NJ, USA) to maintain a superior real-time visuali…
Reproducibility of deep inspiration breath hold with active breathing coordinator: a dosimetric assessment of inter-fractional cardiac dose variation in left-sided partial breast radiotherapy Open
Purpose: Given the increased risk of cardiac toxicity with higher doses, cardiac sparing is crucial for left-sided breast cancer patients. Deep inspiration breath hold (DIBH) is one approach, but its reproducibility is questioned. This stu…
Stereotactic Radiosurgery for Intracranial Breast Metastases: A Systematic Review and Meta-Analysis Open
Background/Objectives: To determine the impact of stereotactic radiosurgery on outcomes of metastatic breast cancer with intracranial metastases. Methods: We systematically searched the PubMed and EMBASE databases for studies published bet…
View article: Optimizing IOL Calculators with Deep Learning Prediction of Total Corneal Astigmatism
Optimizing IOL Calculators with Deep Learning Prediction of Total Corneal Astigmatism Open
Background/Objectives: This study aims to identify the most accurate regression model for predicting total corneal astigmatism (TCA) from anterior corneal astigmatism (ACA) and to fine-tune the best model’s architecture to further optimize…
View article: Race and Ethnicity Representation in Phase 2/3 Oncology Clinical Trial Publications
Race and Ethnicity Representation in Phase 2/3 Oncology Clinical Trial Publications Open
Importance The five 1997 Office of Management and Budget races in the US include American Indian or Alaska Native, Asian, Black or African American, Native Hawaiian or Other Pacific Islander, and White, with Hispanic ethnicity. Despite the…
Range Prediction based on Battery Degradation and Vehicle Mileage for Battery Electric Vehicles Open
Due to their low -carbon and ecologically benign characteristics, electric vehicles are growing in popularity. With the aim of creating electric vehicles that can match or even outperform today's internal combustion engines, extensive stud…
Radiation therapy of renal cell carcinoma skeletal metastases – Does histologic subtype predict progression? Open
Introduction: This investigation assessed whether the following factors were associated with radiographic local progression in bone metastases from renal cell carcinoma (RCC): (1) high-risk histologic features (2) lesional surgery (3) biol…
Artificial Intelligence in Career Counseling: A Test Case with ResumAI Open
The rise of artificial intelligence (AI) has led to various means of integration of AI aimed to provide efficiency in tasks, one of which is career counseling. A key part of getting a job is having a solid resume that passes through the fi…
View article: Consensus recommendations in the management of Ewing sarcoma from the National Ewing Sarcoma Tumor Board
Consensus recommendations in the management of Ewing sarcoma from the National Ewing Sarcoma Tumor Board Open
Ewing sarcoma (ES) is a malignant tumor of bone and soft tissue that most often occurs in adolescents and young adults. Despite an international coordinated approach, several nuances, discrepancies, and debates remain in defining the stand…
View article: Analytical validation of the 7-gene biosignature for prediction of recurrence risk and radiation therapy benefit for breast ductal carcinoma in situ
Analytical validation of the 7-gene biosignature for prediction of recurrence risk and radiation therapy benefit for breast ductal carcinoma in situ Open
Purpose Ductal carcinoma in situ (DCIS), is a noninvasive breast cancer, representing 20-25% of breast cancer diagnoses in the USA. Current treatment options for DCIS include mastectomy or breast-conserving surgery (BCS) with or without ra…
Response to commentary on: A prospective, randomized, parallel group, double blind, multicenter study to compare the efficacy, safety and immunogenicity of Lupin’s ranibizumab with Lucentis in patients with neovascular age-related macular degeneration Open
Dear Editor, We read the succinct commentary by Gopal[1] with great interest and thank him for appreciating our clinical study and its results.[2] As biosimilars are approved based on totality of evidence showing similarity with reference …