Stuart F. Cogan
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View article: Electrochemical stability and neural recording with sputtered ruthenium oxide electrodes subchronically in rat motor cortex
Electrochemical stability and neural recording with sputtered ruthenium oxide electrodes subchronically in rat motor cortex Open
Objective . To investigate sputtered ruthenium oxide (RuO x ) as a low impedance coating for recording neural activity with intracortical microelectrode arrays (MEAs). Approach. RuO x was sputtered onto active sites of amorphous silicon ca…
View article: The Role of Scalp <scp>EEG</scp> Recordings During Cortical Visual Prosthesis Testing
The Role of Scalp <span>EEG</span> Recordings During Cortical Visual Prosthesis Testing Open
Introduction This article highlights the value of recording scalp electroencephalogram (EEG) from two individuals with blindness who received intracortical visual stimulators to create artificial vision. Given the known risk of cortical st…
View article: Amorphous silicon carbide probe mechanics for insertion in the cerebral cortex of rats, pigs, and macaques
Amorphous silicon carbide probe mechanics for insertion in the cerebral cortex of rats, pigs, and macaques Open
Objective. Intracortical microelectrode arrays (MEAs) are implantable devices used for neural recording and stimulation. However, their long-term performance is often compromised due, at least in part, to glial scar formation, initiated by…
View article: Investigating the spatial limits of somatotopic and depth-dependent sensory discrimination stimuli in rats via intracortical microstimulation
Investigating the spatial limits of somatotopic and depth-dependent sensory discrimination stimuli in rats via intracortical microstimulation Open
The somatosensory cortex can be electrically stimulated via intracortical microelectrode arrays (MEAs) to induce a range of vibrotactile sensations. While previous studies have employed multi-shank MEA configurations to map somatotopic rel…
View article: Analysis of electrochemical impedance spectroscopy data for sputtered iridium oxide electrodes
Analysis of electrochemical impedance spectroscopy data for sputtered iridium oxide electrodes Open
Objective . Our objective was to perform a complete analysis of in-vitro impedance data for sputtered iridium oxide film (SIROF) micro-electrodes. The analysis included quantification of the stochastic and bias error structure and developm…
View article: Enhanced Performance of Novel Amorphous Silicon Carbide Microelectrode Arrays in Rat Motor Cortex
Enhanced Performance of Novel Amorphous Silicon Carbide Microelectrode Arrays in Rat Motor Cortex Open
Implantable microelectrode arrays (MEAs) enable the recording of electrical activity from cortical neurons for applications that include brain–machine interfaces. However, MEAs show reduced recording capabilities under chronic implantation…
View article: Enhanced Performance of Novel Amorphous Silicon Carbide Microelectrode Arrays in Rat Motor Cortex
Enhanced Performance of Novel Amorphous Silicon Carbide Microelectrode Arrays in Rat Motor Cortex Open
Implantable microelectrode arrays (MEAs) enable the recording of electrical activity from cortical neurons for applications that include brain machine interfaces. However, MEAs show reduced recording capabilities under chronic implantation…
View article: NeurostimML: a machine learning model for predicting neurostimulation-induced tissue damage
NeurostimML: a machine learning model for predicting neurostimulation-induced tissue damage Open
Objective . The safe delivery of electrical current to neural tissue depends on many factors, yet previous methods for predicting tissue damage rely on only a few stimulation parameters. Here, we report the development of a machine learnin…
View article: Author Correction: Recording of pig neuronal activity in the comparative context of the awake human brain
Author Correction: Recording of pig neuronal activity in the comparative context of the awake human brain Open
View article: Reactive Amine Functionalized Microelectrode Arrays Provide Short-Term Benefit but Long-Term Detriment to <i>In Vivo</i> Recording Performance
Reactive Amine Functionalized Microelectrode Arrays Provide Short-Term Benefit but Long-Term Detriment to <i>In Vivo</i> Recording Performance Open
Intracortical microelectrode arrays (MEAs) are used for recording neural signals. However, indwelling devices result in chronic neuroinflammation, which leads to decreased recording performance through degradation of the device and surroun…
View article: Planar Amorphous Silicon Carbide Microelectrode Arrays for Chronic Recording in Rat Motor Cortex
Planar Amorphous Silicon Carbide Microelectrode Arrays for Chronic Recording in Rat Motor Cortex Open
Chronic implantation of intracortical microelectrode arrays (MEAs) capable of recording from individual neurons can be used for the development of brain-machine interfaces. However, these devices show reduced recording capabilities under c…
View article: The effect of a Mn(III)tetrakis(4-benzoic acid)porphyrin (MnTBAP) coating on the chronic recording performance of planar silicon intracortical microelectrode arrays
The effect of a Mn(III)tetrakis(4-benzoic acid)porphyrin (MnTBAP) coating on the chronic recording performance of planar silicon intracortical microelectrode arrays Open
View article: NeurostimML: A machine learning model for predicting neurostimulation-induced tissue damage
NeurostimML: A machine learning model for predicting neurostimulation-induced tissue damage Open
Objective The safe delivery of electrical current to neural tissue depends on many factors, yet previous methods for predicting tissue damage rely on only a few stimulation parameters. Here, we report the development of a machine learning …
View article: Antioxidant Dimethyl Fumarate Temporarily but Not Chronically Improves Intracortical Microelectrode Performance
Antioxidant Dimethyl Fumarate Temporarily but Not Chronically Improves Intracortical Microelectrode Performance Open
Intracortical microelectrode arrays (MEAs) can be used in a range of applications, from basic neuroscience research to providing an intimate interface with the brain as part of a brain-computer interface (BCI) system aimed at restoring fun…
View article: Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations
Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations Open
Glucose represents the principal brain energy source. Thus, not unexpectedly, genetic glucose transporter 1 (Glut1) deficiency (G1D) manifests with encephalopathy. G1D seizures, which constitute a prominent disease manifestation, often pro…
View article: Antioxidant Dimethyl Fumarate Temporarily but not Chronically Improves Intracortical Microelectrode Performance
Antioxidant Dimethyl Fumarate Temporarily but not Chronically Improves Intracortical Microelectrode Performance Open
Intracortical microelectrode arrays (MEAs) can be used in a range of applications, from basic neuroscience research to providing an intimate interface with the brain as part of a Brain-Computer Interface (BCI) system aimed to restore funct…
View article: Direct laser writing of 3D electrodes on flexible substrates
Direct laser writing of 3D electrodes on flexible substrates Open
This report describes a 3D microelectrode array integrated on a thin-film flexible cable for neural recording in small animals. The fabrication process combines traditional silicon thin-film processing techniques and direct laser writing o…
View article: Behavioral paradigm for the evaluation of stimulation-evoked somatosensory perception thresholds in rats
Behavioral paradigm for the evaluation of stimulation-evoked somatosensory perception thresholds in rats Open
Intracortical microstimulation (ICMS) of the somatosensory cortex via penetrating microelectrode arrays (MEAs) can evoke cutaneous and proprioceptive sensations for restoration of perception in individuals with spinal cord injuries. Howeve…
View article: Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations
Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations Open
Glucose represents the principal brain energy source. Thus, not unexpectedly, genetic glucose transporter 1 (Glut1) deficiency (G1D) manifests with encephalopathy. G1D seizures, which constitute a prominent disease manifestation, often pro…
View article: Behavioral Paradigm for the Evaluation of Stimulation-Evoked Somatosensory Perception Thresholds in Rats
Behavioral Paradigm for the Evaluation of Stimulation-Evoked Somatosensory Perception Thresholds in Rats Open
Intracortical microstimulation (ICMS) of the somatosensory cortex via penetrating microelectrode arrays (MEAs) can evoke cutaneous and proprioceptive sensations for restoration of perception in individuals with spinal cord injuries. Howeve…
View article: Solid state electrochromic light modulator
Solid state electrochromic light modulator Open
An all solid-state variable transmission electrochromic device has a source of charge compensating ions. An inorganic oxide counterelectrode film which on reduction with the accompanying insertion of the charge compensating ions increases …
View article: Chronic Stability of Local Field Potentials Using Amorphous Silicon Carbide Microelectrode Arrays Implanted in the Rat Motor Cortex
Chronic Stability of Local Field Potentials Using Amorphous Silicon Carbide Microelectrode Arrays Implanted in the Rat Motor Cortex Open
Implantable microelectrode arrays (MEAs) enable the recording of electrical activity of cortical neurons, allowing the development of brain-machine interfaces. However, MEAs show reduced recording capabilities under chronic conditions, pro…
View article: Electrochromic material and electro-optical device using same
Electrochromic material and electro-optical device using same Open
An oxidatively coloring electrochromic layer of composition M.sub.y CrO.sub.2+x (0.33.ltoreq.y.ltoreq.2.0 and x.ltoreq.2) where M=Li, Na or K with improved transmittance modulation, improved thermal and environmental stability, and improve…
View article: Author Correction: Recording of pig neuronal activity in the comparative context of the awake human brain
Author Correction: Recording of pig neuronal activity in the comparative context of the awake human brain Open
View article: A Novel 3D Helical Microelectrode Array for In Vitro Extracellular Action Potential Recording
A Novel 3D Helical Microelectrode Array for In Vitro Extracellular Action Potential Recording Open
Recent advances in cell and tissue engineering have enabled long-term three-dimensional (3D) in vitro cultures of human-derived neuronal tissues. Analogous two-dimensional (2D) tissue cultures have been used for decades in combination with…
View article: Recording of pig neuronal activity in the comparative context of the awake human brain
Recording of pig neuronal activity in the comparative context of the awake human brain Open
View article: Chronic stability of activated iridium oxide film voltage transients from wireless floating microelectrode arrays
Chronic stability of activated iridium oxide film voltage transients from wireless floating microelectrode arrays Open
Successful monitoring of the condition of stimulation electrodes is critical for maintaining chronic device performance for neural stimulation. As part of pre-clinical safety testing in preparation for a visual prostheses clinical trial, w…
View article: Direct laser writing of 3D electrodes on flexible substrates
Direct laser writing of 3D electrodes on flexible substrates Open
This report describes a 3D microelectrode array integrated on a thin-film flexible cable for neural recording in small animals. The micro electrode array fabrication process integrates traditional silicon thin-film processing techniques an…
View article: Insertion mechanics of amorphous SiC ultra-micro scale neural probes
Insertion mechanics of amorphous SiC ultra-micro scale neural probes Open
Objective . Trauma induced by the insertion of microelectrodes into cortical neural tissue is a significant problem. Further, micromotion and mechanical mismatch between microelectrode probes and neural tissue is implicated in an adverse f…
View article: The Effect of Implanted Functional Electrical Stimulation on Gait Performance in Stroke Survivors: A Systematic Review
The Effect of Implanted Functional Electrical Stimulation on Gait Performance in Stroke Survivors: A Systematic Review Open
The emerging literature suggests that implantable functional electrical stimulation may improve gait performance in stroke survivors. However, there is no review providing the possible therapeutic effects of implanted functional electrical…