D. Rama Sekhara Reddy
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View article: FORMULATION AND EVALUATION OF AN ORAL TIMED PULSATILE DRUG DELIVERY FOR ALLEVIATING PAIN IN RHEUMATOID ARTHRITIS
FORMULATION AND EVALUATION OF AN ORAL TIMED PULSATILE DRUG DELIVERY FOR ALLEVIATING PAIN IN RHEUMATOID ARTHRITIS Open
Objective: The present study was aimed to formulate and evaluate an oral timed-release pulsatile drug delivery of AcecloFenac (AF) for rheumatoid arthritis pain by the Chronopharmaceutical approach with early morning breakthrough of AF as …
View article: Structural and Magnetic Properties of Y<sub>0.85</sub>La<sub>0.15</sub>Fe<sub>1−(4/3)x</sub>Ti<sub>x</sub>O<sub>3</sub> (where (x = 0, 0.025, 0.05 and 0.075) Nanomaterials Derived from Sol-Gel Route
Structural and Magnetic Properties of Y<sub>0.85</sub>La<sub>0.15</sub>Fe<sub>1−(4/3)x</sub>Ti<sub>x</sub>O<sub>3</sub> (where (x = 0, 0.025, 0.05 and 0.075) Nanomaterials Derived from Sol-Gel Route Open
Y 0.85 La 0.15 Fe 1−(4/3)x Ti x O 3 (where ( x = 0, 0.025, 0.05 and 0.075) nanomaterials were prepared using tartare acid assisted sol-gel method. Various analytical characterization techniques such as X-ray powder diffraction (XRD), scann…
View article: Glass Sintering Aid Effect on Magnetic and Dielectric Properties of YFeO<sub>3</sub> Ceramics
Glass Sintering Aid Effect on Magnetic and Dielectric Properties of YFeO<sub>3</sub> Ceramics Open
YFeO 3 (YFO) and optimized glass wt% [0.5Li 2 O-0.5K 2 O-2B 2 O 3 (LKBO) and BaO-Bi 2 O 3 -B 2 O 3 (BBBO)] as a sintering aid in YFO ceramics were fabricated using fine powders prepared from sol-gel technique. Pure YFO and glass sintering …
View article: FORMULATION AND EVALUATION OF MODIFIED PULSATILE CAPSULE FOR CHRONOPHARMACOTHERAPY OF RHEUMATOID ARTHRITIC PAIN
FORMULATION AND EVALUATION OF MODIFIED PULSATILE CAPSULE FOR CHRONOPHARMACOTHERAPY OF RHEUMATOID ARTHRITIC PAIN Open
Objective: The objective of the present study was to design and evaluate pulsincap system for chrono pharmacotherapy of rheumatoid arthritis that combines advantages of both immediate and sustained release technology with the suitable dela…
View article: Synthesis of CoFe<sub>2</sub>O<sub>4</sub> Nanomaterials via Sol–Gel Auto‐Combustion Method using Different Chelating Agent, and Its Effects on Magnetic and Dielectric Properties
Synthesis of CoFe<sub>2</sub>O<sub>4</sub> Nanomaterials via Sol–Gel Auto‐Combustion Method using Different Chelating Agent, and Its Effects on Magnetic and Dielectric Properties Open
Herein, the structural and magnetic properties of cobalt ferrite (CoFe 2 O 4 [CFO]) nanomaterials obtained from sol–gel auto‐combustion method using different chelating agent (tartaric acid, citric acid, and oxalic acid) are reported. The …
View article: Synthesis, magnetic, AC conductivity and dielectric properties of hematite nanocrystallites
Synthesis, magnetic, AC conductivity and dielectric properties of hematite nanocrystallites Open
We are reporting the synthesis along with magnetic, ac conductivity and dielectric properties of hematite nanocrystallites. The prepared Fe2O3 is crystallizing in corundum structure which belongs to the rhombohedron system with the space g…
View article: UPLC method development and validation for simultaneous determination of amlodipine besylate and enalapril maleate in drug products
UPLC method development and validation for simultaneous determination of amlodipine besylate and enalapril maleate in drug products Open
Objective: A simple, Accurate, precise method was developed for the simultaneous estimation of the Amlodipine besylate and Enalapril maleate in pharmaceutical dosage form. Methods: Chromatogram was run through BEH C18 column (2.1 × 50mm i.…
View article: ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF DEXMETHYLPHENIDATE AND SERDEXMETHYLPHENIDATE BY USING RP-HPLC IN BULK AND PHARMACEUTICAL DOSAGE FORM
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF DEXMETHYLPHENIDATE AND SERDEXMETHYLPHENIDATE BY USING RP-HPLC IN BULK AND PHARMACEUTICAL DOSAGE FORM Open
Objective: The current investigation was pointed at developing and progressively validating novel, simple, responsive and stable RP-HPLC method for the simultaneous measurement of active pharmaceutical ingredients of Dexmethylphenidate and…
View article: Design, Synthesis, Hypoglycemic Activity and Molecular Docking Studies of 3-substituted-5- [(furan-2-yl)-methylene]-thiazolidine-2,4-dione Derivatives
Design, Synthesis, Hypoglycemic Activity and Molecular Docking Studies of 3-substituted-5- [(furan-2-yl)-methylene]-thiazolidine-2,4-dione Derivatives Open
Background: From the wide range of previous literature studies indicated that thiazolidinedione's reacts with substituted benzaldehydes undergoes knoevenagel condensation gives respective arylidene derivatives. In our attempt all the title…
View article: Determination of obeticholic acid and its glycine conjugate in human plasma using liquid chromatography-tandem mass spectrometry
Determination of obeticholic acid and its glycine conjugate in human plasma using liquid chromatography-tandem mass spectrometry Open
A sensitive and selective liquid chromatography/tandem mass spectrometry method was recommended by the authors for the determination orally bioavailable farnesoid X receptor agonist obeticholic acid along with its glycine conjugate glycoob…
View article: SYNTHESIS AND CHARACTERIZATION OF ISOMERS OF COX-2 INHIBITOR, CELECOXIB
SYNTHESIS AND CHARACTERIZATION OF ISOMERS OF COX-2 INHIBITOR, CELECOXIB Open
Celecoxib is chemically known as 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1yl] benzene sulfonamide. The present work describes the identification, origin, synthesis, characterization and control of isomeric compounds of Celecox…
View article: Green synthesis, characterization and application study of zinc nano particles synthesized using aqueous root extract of Sphagneticola trilobata lin
Green synthesis, characterization and application study of zinc nano particles synthesized using aqueous root extract of Sphagneticola trilobata lin Open
In the present investigation, we have described the green biosynthesis of Zinc nanoparticles (ZnNPs) using aqueous root extract of Sphagneticola trilobata Lin as capping agent. The antioxidant, anti-diabetic and antimicrobial activities of…
View article: Synthesis and Characterization of Novel Analogues of Lopinavir
Synthesis and Characterization of Novel Analogues of Lopinavir Open
The present work describes the identification, origin, synthesis, characterization and control of four novel analogues of lopinavir viz. leucine analogue of lopinavir, isoleucine analogue of lopinavir, methyl analogue of lopinavir and dihy…
View article: Synthesis and Characterization of Novel Analogues of Cefpodoxime Proxetil
Synthesis and Characterization of Novel Analogues of Cefpodoxime Proxetil Open
The present work describes the origin, identification, synthesis, characterization and control of four novel analogues of cefpodoxime proxetil, which are ethyl, methyl, propyl and N-propyl analogues of cefpodoxime proxetil.