Silvio Däster
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View article: Immuno-Activated, Highly Expressing PD-1 Phenotype in Hepatocellular Carcinoma Is Associated with a Lower Recurrence Rate
Immuno-Activated, Highly Expressing PD-1 Phenotype in Hepatocellular Carcinoma Is Associated with a Lower Recurrence Rate Open
Introduction: Curative treatments in early-stage hepatocellular carcinoma (HCC) are limited by high recurrence rates, and targeted therapies against HCC are rare. Tumour microenvironment (TME) plays a crucial role. One strategy is the expr…
View article: Impact of Positive Lymph Nodes after Systematic Perihilar Lymphadenectomy in Colorectal Liver Metastases
Impact of Positive Lymph Nodes after Systematic Perihilar Lymphadenectomy in Colorectal Liver Metastases Open
Background: 25 to 50% of patients suffering from colorectal cancer develop liver metastases. The incidence of regional lymph node (LN) metastases within the liver is up to 14%. The need for perihilar lymph node dissection (LND) is still a …
Long-Term Quality of Life after Hybrid Robot-assisted and Open Ivor Lewis Esophagectomy for Esophageal Cancer in a Single Center: a Comparative Analysis Open
Purpose Due to improved survival of esophageal cancer patients, long-term quality of life (QoL) is increasingly gaining importance. We analyzed QoL of patients treated with open Ivor Lewis esophagectomy (Open-E) or a hybrid operation inclu…
Omission of perioperative morphine reduces postoperative pain in proctological interventions: a single-center analysis Open
There is an increase in outpatient procedures and this trend will continue in the future. For hemorrhoidectomy, it is the standard of treatment in many health care systems. Perioperative management including adequate pain control is of par…
The short- and long-term outcome after the surgical management of common bile duct stones in a tertiary referral hospital Open
Background The removal of common bile duct stones by endoscopic retrograde cholangiopancreatography (ERCP) shows excellent results with low complication rates and is therefore considered a gold standard. However, in case of stones non-remo…
Supplementary Figure Legends from Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer Open
Figure Legends for Supplementary Figures 1-6
Supplementary Tables from Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer Open
Supplementary Tables 1-5
Supplementary Tables from Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer Open
Supplementary Tables 1-5
Supplementary Figures from Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer Open
Supplementary figures 1-6
Data from Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer Open
Immune cell infiltration in colorectal cancer effectively predicts clinical outcome. IL22, produced by immune cells, plays an important role in inflammatory bowel disease, but its relevance in colorectal cancer remains unclear. Here, we ad…
Supplementary Figures from Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer Open
Supplementary figures 1-6
Supplementary Figure Legends from Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer Open
Figure Legends for Supplementary Figures 1-6
Data from Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer Open
Immune cell infiltration in colorectal cancer effectively predicts clinical outcome. IL22, produced by immune cells, plays an important role in inflammatory bowel disease, but its relevance in colorectal cancer remains unclear. Here, we ad…
Supplementary Figure 2 from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Co-culture with PBNs does not impact on growth of CRC cell lines. (A) PBNs from healthy donors (HD) were co-cultured with 6 different CRC cell lines at a CRC: PBN ratio 1: 20, as described in “materials and methodsâ€�. After 72h, tumour …
Legend from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Supplementary legend figures
Supplementary Table 2 from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Clinical-phatological characteristics of the CRC patient cohort and their association with levels of CD8+ and CD66b+ cell infiltrate.
Supplementary Figure 3 from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
CD8+/PBN cross-talk is contact dependent. (A) Cumulative flow-cytometry histograms documenting CD69 expression in CD8+ T cells activated by using different concentrations of surface bound anti-CD3 (TR66, 0.5 and 2μg/ml) and soluble anti C…
Supplementary Table 1 from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Clinical-phatological characteristics of the CRC patient cohort and their association with levels of CD66b+ cell infiltrate.
Data from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Purpose: Tumor infiltration by different T lymphocyte subsets is known to be associated with favorable prognosis in colorectal cancer. Still debated is the role of innate immune system. We investigated clinical relevance, phenotypes, and f…
Supplementary Table 2 from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Clinical-phatological characteristics of the CRC patient cohort and their association with levels of CD8+ and CD66b+ cell infiltrate.
Supplementary Figure 3 from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
CD8+/PBN cross-talk is contact dependent. (A) Cumulative flow-cytometry histograms documenting CD69 expression in CD8+ T cells activated by using different concentrations of surface bound anti-CD3 (TR66, 0.5 and 2μg/ml) and soluble anti C…
Data from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Purpose: Tumor infiltration by different T lymphocyte subsets is known to be associated with favorable prognosis in colorectal cancer. Still debated is the role of innate immune system. We investigated clinical relevance, phenotypes, and f…
Legend from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Supplementary legend figures
Supplementary Figure 2 from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Co-culture with PBNs does not impact on growth of CRC cell lines. (A) PBNs from healthy donors (HD) were co-cultured with 6 different CRC cell lines at a CRC: PBN ratio 1: 20, as described in “materials and methodsâ€�. After 72h, tumour …
Supplementary Figure 1 from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Comparative phenotypic analysis of peripheral blood neutrophils from healthy donors and patients with CRC.
Supplementary Table 1 from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Clinical-phatological characteristics of the CRC patient cohort and their association with levels of CD66b+ cell infiltrate.
Supplementary Figure 1 from The Interplay Between Neutrophils and CD8<sup>+</sup> T Cells Improves Survival in Human Colorectal Cancer Open
Comparative phenotypic analysis of peripheral blood neutrophils from healthy donors and patients with CRC.
View article: Comprehensive Treatment Algorithms of the Swiss Peritoneal Cancer Group for Peritoneal Cancer of Gastrointestinal Origin
Comprehensive Treatment Algorithms of the Swiss Peritoneal Cancer Group for Peritoneal Cancer of Gastrointestinal Origin Open
Peritoneal cancer (PC) is a dire finding, yet in selected patients, long-term survival is possible. Complete cytoreductive surgery (CRS) together with combination immunochemotherapy is essential to achieve cure. Hyperthermic intraperitonea…