Simon Dixon
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View article: Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms: FUTURE, a superiority RCT and economic evaluation
Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms: FUTURE, a superiority RCT and economic evaluation Open
Background Overactive bladder is a common problem affecting the United Kingdom adult female population. Symptoms include urinary urgency, with or without urgency incontinence, increased daytime urinary frequency and nocturia. Initial conse…
View article: Tourists’ Motivation in Focus: Contrasting Push and Pull Factors of Tuba’s Adventure Tourism
Tourists’ Motivation in Focus: Contrasting Push and Pull Factors of Tuba’s Adventure Tourism Open
This study examined the motivational factors that influence participation in soft and hard adventure tourism in Tuba, Benguet. Soft adventure activities in the area include camping, swimming, and nature walks, while hard adventures involve…
View article: Long‐term cost‐effectiveness of invasive urodynamic studies for overactive bladder in women
Long‐term cost‐effectiveness of invasive urodynamic studies for overactive bladder in women Open
Objectives To estimate the cost‐effectiveness of using invasive urodynamic studies (UDS) in the management of women with refractory overactive bladder (OAB) symptoms using the results of the FUTURE trial. Patients and Methods The FUTURE st…
View article: Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms (FUTURE) in the UK: a multicentre, superiority, parallel, open-label, randomised controlled trial
Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms (FUTURE) in the UK: a multicentre, superiority, parallel, open-label, randomised controlled trial Open
UK National Institute for Health and Care Research Health Technology Assessment Programme.
View article: Increasing uptake of self-management education programmes for type 2 diabetes in primary care: the Embedding research programme including an RCT
Increasing uptake of self-management education programmes for type 2 diabetes in primary care: the Embedding research programme including an RCT Open
Background Self-management education and support programmes help people with type 2 diabetes to manage their diabetes better. However, most people do not attend these programmes. Objective Increase type 2 diabetes self-management programme…
View article: Derivation of a South African tariff for the EQ-5D-5L using a personal utility function approach
Derivation of a South African tariff for the EQ-5D-5L using a personal utility function approach Open
Objectives This study’s primary objective was to test the feasibility of using the online personal utility function (OPUF) approach and develop a preliminary utility tariff for the EQ-5D-5L based on a South African community sample. Method…
View article: Sheffield Adaptive Patterned Electrical Stimulation (SHAPES) Therapy for Post Stroke Arm spasticity: study protocol for a 3-arm, a partially blinded, randomised controlled trial
Sheffield Adaptive Patterned Electrical Stimulation (SHAPES) Therapy for Post Stroke Arm spasticity: study protocol for a 3-arm, a partially blinded, randomised controlled trial Open
Introduction Post stroke elbow spasticity (PSES) affects over a third of individuals following stroke and negatively impacts on functional recovery, comfort and quality of life. Drug therapies have limited efficacy and unwanted side effect…
View article: Take-home naloxone in multicentre emergency settings: the TIME feasibility cluster RCT
Take-home naloxone in multicentre emergency settings: the TIME feasibility cluster RCT Open
Background Opioids kill more people than any other drug. Naloxone is an opioid antagonist which can be distributed in take-home ‘kits’ for peer administration (take-home naloxone). Aim To determine the feasibility of carrying out a definit…
View article: Sheffield Adaptive Patterned Electrical Stimulation (SHAPES) Therapy for Post Stroke Arm Spasticity: study protocol for a 3-arm, a partially blinded, randomised controlled trial
Sheffield Adaptive Patterned Electrical Stimulation (SHAPES) Therapy for Post Stroke Arm Spasticity: study protocol for a 3-arm, a partially blinded, randomised controlled trial Open
Introduction Post stroke elbow spasticity (PSES) affects over a third of individuals following stroke and negatively impacts on functional recovery, comfort and quality of life. Drug therapies have limited efficacy and unwanted side effect…
View article: Is a definitive trial of Take-Home Naloxone in emergency settings indicated? Results of a cluster randomised feasibility study
Is a definitive trial of Take-Home Naloxone in emergency settings indicated? Results of a cluster randomised feasibility study Open
Background Opioids kill more people than any other class of drug. Naloxone is an opioid antagonist which can be distributed in kits for peer administration. We aimed to determine feasibility of undertaking a definitive randomised controlle…
View article: The impact of digital technology in care homes on unplanned secondary care usage and associated costs
The impact of digital technology in care homes on unplanned secondary care usage and associated costs Open
Background A substantial number of Emergency Department (ED) attendances by care home residents are potentially avoidable. Health Call Digital Care Homes is an app-based technology that aims to streamline residents’ care by recording their…
View article: Behaviour change intervention for toothbrushing (lesson and text messages) to prevent dental caries in secondary school pupils: The BRIGHT randomized control trial
Behaviour change intervention for toothbrushing (lesson and text messages) to prevent dental caries in secondary school pupils: The BRIGHT randomized control trial Open
Objectives This multicentre, assessor‐blinded, two‐arm cluster randomized trial evaluated the clinical and cost‐effectiveness of a behaviour change intervention promoting toothbrushing for preventing dental caries in UK secondary schools. …
View article: Examining productivity losses associated with health related quality of life using patient data
Examining productivity losses associated with health related quality of life using patient data Open
This report presents the findings of a study that estimates productivity loss due to poor health, using days off paid employment and normal activities, EQ-5D and International Classification of Disease (ICD) chapter, as well as socio-demog…
View article: PIII Project Overview and Status
PIII Project Overview and Status Open
The Proton Improvement Plan II (PIP-II) project is an essential upgrade to Fermilab's particle accelerator complex to enable the world's most intense neutrino beam for LBNF/DUNE and a broad particle physics program for many decades to come…
View article: Real world evidence supports waking salivary cortisone as a screening test for adrenal insufficiency
Real world evidence supports waking salivary cortisone as a screening test for adrenal insufficiency Open
Objective Worldwide, adults and children are at risk of adrenal insufficiency largely due to infectious diseases and adrenal suppression from use of anti‐inflammatory glucocorticoids. Home waking salivary cortisone is an accurate screening…
View article: OR30-01 Waking Salivary 11-hydroxyandrostenedione And Cortisone As A Novel Non-invasive Test For Adrenal Insufficiency
OR30-01 Waking Salivary 11-hydroxyandrostenedione And Cortisone As A Novel Non-invasive Test For Adrenal Insufficiency Open
Disclosure: N.R. Lawrence: None. B.G. Keevil: None. C. Elder: None. J. Fearnside: None. S. Caunt: None. S. Dixon: None. J.D. Newell-Price: Consulting Fee; Self; Diurnal, Recordati, Crinetics, HRA Pharma. R.J. Ross: Employee; Self; Diurnal.…
View article: Cost-Effectiveness of Robot-Assisted Radical Cystectomy vs Open Radical Cystectomy for Patients With Bladder Cancer
Cost-Effectiveness of Robot-Assisted Radical Cystectomy vs Open Radical Cystectomy for Patients With Bladder Cancer Open
Importance The value to payers of robot-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) when compared with open radical cystectomy (ORC) for patients with bladder cancer is unclear. Objectives To compare the cost-…
View article: The Impact of Digital Technology in Care Homes on Unplanned Secondary Care Usage and Associated Costs
The Impact of Digital Technology in Care Homes on Unplanned Secondary Care Usage and Associated Costs Open
Background A substantial number of emergency department (ED) attendances from care homes could be classed as avoidable. HealthCall is a technology that aims to streamline residents’ care by recording their observations electronically. Obse…
View article: The impacts of diagnosis-intervention packet payment on the providers’ behavior of inpatient care—evidence from a national pilot city in China
The impacts of diagnosis-intervention packet payment on the providers’ behavior of inpatient care—evidence from a national pilot city in China Open
Background In 2020, the Chinese government developed and implemented an innovative case-based payment method under the regional global budget called the diagnosis-intervention packet (DIP) payment to pay for inpatient care. This study aims…
View article: Behaviour change intervention (education and text) to prevent dental caries in secondary school pupils: BRIGHT RCT, process and economic evaluation
Behaviour change intervention (education and text) to prevent dental caries in secondary school pupils: BRIGHT RCT, process and economic evaluation Open
Background The presence of dental caries impacts on children’s daily lives, particularly among those living in deprived areas. There are successful interventions across the United Kingdom for young children based on toothbrushing with fluo…
View article: Prefacing unexplored archives from Central Andean surface-to-bedrock ice cores through a multifaceted investigation of regional firn and ice core glaciochemistry
Prefacing unexplored archives from Central Andean surface-to-bedrock ice cores through a multifaceted investigation of regional firn and ice core glaciochemistry Open
Shallow firn cores, in addition to a near-basal ice core, were recovered in 2018 from the Quelccaya ice cap (5470 m a.s.l) in the Cordillera Vilcanota, Peru, and in 2017 from the Nevado Illimani glacier (6350 m a.s.l) in the Cordillera Rea…