Durdu Karasoy
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View article: A two-stage approach for Bayesian parametric joint modelling of longitudinal and Weibull accelerated failure time data
A two-stage approach for Bayesian parametric joint modelling of longitudinal and Weibull accelerated failure time data Open
Since longitudinal and survival data are often obtained together in applications, studies on joint modelling that reveal the relationship between these two data have increased considerably in recent years. These models are generally define…
View article: Oncological results in primary and secondary malignant chest wall tumors
Oncological results in primary and secondary malignant chest wall tumors Open
Background: This study aims to evaluate the oncological results of primary and secondary chest wall tumors treated with curative resections and to investigate possible prognostic factors. Methods: Between January 2010 and December 2021, a …
View article: A new adjusted Bayesian method in Cox regression model with covariate subject to measurement error
A new adjusted Bayesian method in Cox regression model with covariate subject to measurement error Open
An important bias can occur when estimating coefficients by maximizing the known partial likelihood function in the Cox regression model with the measurement error covariate. We focus here on Bayesian methods in order to adjust measurement…
View article: HER2 Amplification by Next-Generation Sequencing in Lung Carcinoma: A Comparison of NGS Amplified and Non-amplified Cases by Immunohistochemistry and In Situ Hybridization
HER2 Amplification by Next-Generation Sequencing in Lung Carcinoma: A Comparison of NGS Amplified and Non-amplified Cases by Immunohistochemistry and In Situ Hybridization Open
Until the effects of HER2 amplification on the HER2 protein are well understood and pulmonary carcinoma algorithms are defined, non-small cell lung carcinomas found to be amplified by next-generation sequencing should be verified by additi…
View article: Is Enoxaparin Sodium Exactly Safe For Subcutaneous Fibroblast?: A Cell Culture Study
Is Enoxaparin Sodium Exactly Safe For Subcutaneous Fibroblast?: A Cell Culture Study Open
Aim: Despite relatively low amount in the subcutaneous tissue, fibroblasts play a critical role in the continuity of intercellular connections, maintenance of tissue integrity, and forming a balanced fascial network. Enoxaparin sodium is w…
View article: Joint Modeling of a Longitudinal Measurement and Parametric Survival Data with Application to Primary Biliary Cirrhosis Study
Joint Modeling of a Longitudinal Measurement and Parametric Survival Data with Application to Primary Biliary Cirrhosis Study Open
Although longitudinal and survival data are collected in the same study, they are usually analyzed separately. Measurement errors and missing data problems arise because of separate analysis of these two data. Therefore, joint model should…
View article: A link between cytotoxicity in cell culture and gastrointestinal side effects of oral anticoagulants: bench-to-bedside
A link between cytotoxicity in cell culture and gastrointestinal side effects of oral anticoagulants: bench-to-bedside Open
Gastrointestinal side effect profiles of these four agents in a real-life setting is consistent with the results obtained from the present study. There is no sole factor with the potential of explaining the entire gastrointestinal side eff…
View article: Vascular endothelial growth factor (VEGF)-C, VEGF-D, VEGFR-3 and D2-40 expressions in primary breast cancer: Association with lymph node metastasis
Vascular endothelial growth factor (VEGF)-C, VEGF-D, VEGFR-3 and D2-40 expressions in primary breast cancer: Association with lymph node metastasis Open
Our results support that examination of VEGF-D expression in breast cancer cells may be beneficial in the identification of lymph node metastasis.
View article: Effect of tumor size on survival in pn0m0 non-small cell lung cancer patients
Effect of tumor size on survival in pn0m0 non-small cell lung cancer patients Open
Background: Tumor size is one of the major prognostic determinants of non-small cell lung cancer (NSCLC).In the present study, we evaluated the effect of tumor size on survival in pN0M0 NSCLC patients.Between 1994Between and 2013Between , …
View article: Outliers in Survival Analysis
Outliers in Survival Analysis Open
Survival analysis is a collection of statistical methods for analyzing data where the outcome variable is the time until the occurrence of an event of interest. Outliers in survival anaysis calculated differently from classical regression …
View article: Thrombophilic polymorphisms are not associated with disease-free survival in breast cancer patients.
Thrombophilic polymorphisms are not associated with disease-free survival in breast cancer patients. Open
Our study suggests that thrombophilic polymorphisms are not associated with DFS when the proportional odds model is applied.