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View article: Intraventricular pressure and volume during conventional and automated head-up CPR
Intraventricular pressure and volume during conventional and automated head-up CPR Open
A fundamental and inherent shortcoming of C-CPR, limited cardiac stroke volume, and resultant forward flow, can be overcome with AHUP-CPR. These findings may help explain the better outcomes associated with early use of AHUP-CPR.
View article: Population cessation of aspirin use for the prevention of cardiovascular disease
Population cessation of aspirin use for the prevention of cardiovascular disease Open
Clinicaltrials.gov registered on December 1, 2014, NCT02607917.
View article: The Effect of Protein Intake on Bone Disease, Kidney Disease, and Sarcopenia: A Systematic Review
The Effect of Protein Intake on Bone Disease, Kidney Disease, and Sarcopenia: A Systematic Review Open
View article: Active decompression during automated head-up cardiopulmonary resuscitation
Active decompression during automated head-up cardiopulmonary resuscitation Open
Full chest wall lift, achieved with ≥ 3 cm of AD, was needed to maintain and optimize hemodynamics during AHUP-CPR in pigs. These findings should be considered when optimizing care with this new approach.
View article: C-75 | Comparison of the Cost of Care of Eluvia versus Zilver PTX in Treating Femoropopliteal Artery Disease
C-75 | Comparison of the Cost of Care of Eluvia versus Zilver PTX in Treating Femoropopliteal Artery Disease Open
Despite the use of endovascular femoropopliteal artery interventions (FPA), limited data exist regarding FPA intervention cost implications. This study quantified the cost of care during the index procedure and up to 2 years post-discharge…
View article: Nurse Staffing And Quality Of Patient Care.
Nurse Staffing And Quality Of Patient Care. Open
Increased nursing staffing in hospitals was associated with lower hospital-related mortality, failure to rescue, and other patient outcomes, but the association is not necessarily causal. The effect size varied with the nurse staffing meas…
View article: Diversity in randomized clinical trials for peripheral artery disease: a systematic review
Diversity in randomized clinical trials for peripheral artery disease: a systematic review Open
Background Significant race and sex disparities exist in the prevalence, diagnosis, and outcomes of peripheral artery disease (PAD). However, clinical trials evaluating treatments for PAD often lack representative patient populations. This…
View article: Echocardiogram Utilization and its Association with All-Cause In-Hospital Mortality in Hospitalized Adults with Isolated Traumatic Brain Injury: Propensity-Matched Analysis of the National Inpatient Sample 2016-2020
Echocardiogram Utilization and its Association with All-Cause In-Hospital Mortality in Hospitalized Adults with Isolated Traumatic Brain Injury: Propensity-Matched Analysis of the National Inpatient Sample 2016-2020 Open
View article: Regular aspirin use among a sample of American Indians/Alaskan Natives in the Upper Midwest region of the United States
Regular aspirin use among a sample of American Indians/Alaskan Natives in the Upper Midwest region of the United States Open
View article: Hemodynamics, survival and neurological function with early versus delayed automated head-up CPR in a porcine model of prolonged cardiac arrest
Hemodynamics, survival and neurological function with early versus delayed automated head-up CPR in a porcine model of prolonged cardiac arrest Open
When delivered early rather than late, AHUP-CPR resulted in significantly increased hemodynamics, 24-hour survival, and improved neurological function in pigs after prolonged cardiac arrest. Based on these findings, AHUP-CPR should be cons…
View article: Diversity in clinical trial inclusion for peripheral artery disease lower extremity endovascular interventions: a systematic review protocol
Diversity in clinical trial inclusion for peripheral artery disease lower extremity endovascular interventions: a systematic review protocol Open
Aim: This review provides a study protocol for a systematic review of peripheral artery disease (PAD) clinical trials to examine the eligibility criteria, demographic representation, and enrollment strategies among PAD patients undergoing …
View article: Racial and Ethnic Disparities in Treatment of Critical Limb Ischemia: A National Perspective
Racial and Ethnic Disparities in Treatment of Critical Limb Ischemia: A National Perspective Open
Background Recent guidelines have emphasized the use of medical management, early diagnosis, and a multidisciplinary team to effectively treat patients with critical limb ischemia (CLI). Previous literature briefly highlighted the current …
View article: Aspirin use for primary prevention in older adults
Aspirin use for primary prevention in older adults Open
Aspirin use for cardiovascular disease (CVD) prevention is common among adults 60 years and older.1 Although some use aspirin for secondary prevention, many older adults use daily aspirin for primary prevention despite guidelines recommend…
View article: Performance of Computed Tomographic Angiography–Based Aortic Valve Area for Assessment of Aortic Stenosis
Performance of Computed Tomographic Angiography–Based Aortic Valve Area for Assessment of Aortic Stenosis Open
Background A total of 40% of patients with severe aortic stenosis (AS) have low‐gradient AS, raising uncertainty about AS severity. Aortic valve calcification, measured by computed tomography (CT), is guideline‐endorsed to aid in such case…
View article: What interventions keep older people out of nursing homes? A systematic review and <scp>meta‐analysis</scp>
What interventions keep older people out of nursing homes? A systematic review and <span>meta‐analysis</span> Open
Background Nursing home admission remains a central outcome in many healthcare systems and community‐based programs. The objective of this meta‐analysis was to determine the efficacy of pharmacological and nonpharmacological interventions …
View article: <i>Circulation</i> Editors and Editorial Board
<i>Circulation</i> Editors and Editorial Board Open
View article: Statin Therapy in Persons Receiving Dialysis—Does Peripheral Artery Disease Change the Equation?
Statin Therapy in Persons Receiving Dialysis—Does Peripheral Artery Disease Change the Equation? Open
Hao-Yun Lo, MD; Yu-Sheng Lin, MD, PhD; Donna Shu-Han Lin, MD; Jen-Kuang Lee, MD, PhD; Wen-Jone Chen, MD, PhD
View article: Head and thorax elevation during cardiopulmonary resuscitation using circulatory adjuncts is associated with improved survival
Head and thorax elevation during cardiopulmonary resuscitation using circulatory adjuncts is associated with improved survival Open
Compared with C-CPR controls, rapid initiation of ACE-CPR was associated with a higher likelihood of survival to hospital discharge after OHCA.
View article: Hypotension on cardiopulmonary stress test predicts 90 day mortality after LVAD implantation in INTERMACS 3–6 patients
Hypotension on cardiopulmonary stress test predicts 90 day mortality after LVAD implantation in INTERMACS 3–6 patients Open
Aims Cardiopulmonary stress test (CPX) is routinely performed when evaluating patient candidacy for left ventricular assist device (LVAD) implantation. The predictive value of hypotensive systolic blood pressure (SBP) response during CPX o…
View article: Baroreflex activation therapy with the <scp>Barostim</scp>™ device in patients with heart failure with reduced ejection fraction: a patient level meta‐analysis of randomized controlled trials
Baroreflex activation therapy with the <span>Barostim</span>™ device in patients with heart failure with reduced ejection fraction: a patient level meta‐analysis of randomized controlled trials Open
Aims Heart failure with reduced ejection fraction (HFrEF) remains associated with high morbidity and mortality, poor quality of life (QoL) and significant exercise limitation. Sympatho‐vagal imbalance has been shown to predict adverse prog…
View article: Association of a Community Population and Clinic Education Intervention Program With Guideline-Based Aspirin Use for Primary Prevention of Cardiovascular Disease
Association of a Community Population and Clinic Education Intervention Program With Guideline-Based Aspirin Use for Primary Prevention of Cardiovascular Disease Open
ClinicalTrials.gov Identifier: NCT02607917.
View article: Mortality in Pulmonary Arterial Hypertension in the Modern Era: Early Insights From the Pulmonary Hypertension Association Registry
Mortality in Pulmonary Arterial Hypertension in the Modern Era: Early Insights From the Pulmonary Hypertension Association Registry Open
Background Current mortality data for pulmonary arterial hypertension (PAH) in the United States are based on registries that enrolled patients prior to 2010. We sought to determine mortality in PAH in the modern era using the PHAR (Pulmon…
View article: Inappropriate sinus tachycardia: an examination of existing definitions
Inappropriate sinus tachycardia: an examination of existing definitions Open
Aims Inappropriate sinus tachycardia (IST) is a syndrome characterized by an elevated sinus rate unassociated with known physiological, pathological, or pharmacological causes. Despite published consensus documents, IST definitions appear …
View article: Left Ventricular Mechanics Differ in Subtypes of Aortic Stenosis Following Transcatheter Aortic Valve Replacement
Left Ventricular Mechanics Differ in Subtypes of Aortic Stenosis Following Transcatheter Aortic Valve Replacement Open
Background Left ventricular (LV) mechanics are impaired in patients with severe aortic stenosis (AS). We hypothesized that there would be differences in myocardial mechanics, measured by global longitudinal strain (GLS) recovery in patient…
View article: Association of Cardiovascular Disease Risk Factors With Sociodemographic Characteristics and Health Beliefs Among a Community-Based Sample of African American Adults in Minnesota
Association of Cardiovascular Disease Risk Factors With Sociodemographic Characteristics and Health Beliefs Among a Community-Based Sample of African American Adults in Minnesota Open
View article: What Keeps Older People out of Nursing Homes? A Meta-Analysis
What Keeps Older People out of Nursing Homes? A Meta-Analysis Open
Perhaps one of the most examined, and costly, health transitions older people experience is nursing home admission. In addition to the financial costs nursing home admission poses to older people, their families, and other payers (e.g., th…
View article: Interplay of CT Coronary Plaque Characteristics and Ischemia to Predict Adverse Outcomes
Interplay of CT Coronary Plaque Characteristics and Ischemia to Predict Adverse Outcomes Open
In 134 patients with stable coronary artery disease, high-risk plaque features at CT and physiologic stenosis were found to act in a synergistic fashion to predict adverse outcomes.
View article: Faster time to automated elevation of the head and thorax during cardiopulmonary resuscitation increases the probability of return of spontaneous circulation
Faster time to automated elevation of the head and thorax during cardiopulmonary resuscitation increases the probability of return of spontaneous circulation Open
Faster time to deployment of an AHUP based bundle of care is associated with higher incidence of ROSC. This must be considered when evaluating and implementing this bundle.
View article: News coverage about aspirin as a countervailing force against low-dose aspirin campaign promotion
News coverage about aspirin as a countervailing force against low-dose aspirin campaign promotion Open
Organized health promotion efforts sometimes compete with news media, social media, and other sources when providing recommendations for healthy behavior. In recent years, patients have faced a complicated information environment regarding…
View article: Mortality in Pulmonary Arterial Hypertension in the Modern Era: Early Insights from the Pulmonary Hypertension Association Registry
Mortality in Pulmonary Arterial Hypertension in the Modern Era: Early Insights from the Pulmonary Hypertension Association Registry Open
Introduction:Current mortality data for pulmonary arterial hypertension (PAH) in the US are based on registries that enrolled patients prior to 2010.However, there have been many advancements in PAH therapeutics and development of evidence…