Girish Dwivedi
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View article: Persistent lung and vascular inflammation in mild to moderate COVID-19 survivors detected by ¹⁸F-FDG PET/CT: A quantitative imaging study with implications for cardiovascular risk
Persistent lung and vascular inflammation in mild to moderate COVID-19 survivors detected by ¹⁸F-FDG PET/CT: A quantitative imaging study with implications for cardiovascular risk Open
Persistent pulmonary inflammation is evident following mild-to-moderate COVID-19 and is associated with increased vascular inflammation. These findings suggest a mechanistic link between post-infectious lung and vascular inflammation, pote…
View article: Clonal hematopoiesis of indeterminate potential: a unifying mechanism linking metainflammation and cardiometabolic diseases
Clonal hematopoiesis of indeterminate potential: a unifying mechanism linking metainflammation and cardiometabolic diseases Open
Clonal hematopoiesis of indeterminate potential (CHIP) refers to the age-related expansion of hematopoietic stem cells bearing somatic mutations in the absence of overt hematological malignancy. Emerging evidence suggests that CHIP is not …
View article: Neck-focused Remote Photoplethysmography (rPPG): A comparative study using clinical data and the PyVHR framework
Neck-focused Remote Photoplethysmography (rPPG): A comparative study using clinical data and the PyVHR framework Open
Remote Photoplethysmography (rPPG) promises to turn digital cameras into medical devices with the measurement of heart rates, oxygen saturation and the diagnosis arrhythmias already demonstrated. The face-centric nature of current rPPG tec…
View article: Real-World Prescribing of Renal and Cardiovascular Protective Drugs in Patients With Type 2 Diabetes and Chronic Kidney Disease: Analysis of Data From a Western Australian Quaternary Hospital
Real-World Prescribing of Renal and Cardiovascular Protective Drugs in Patients With Type 2 Diabetes and Chronic Kidney Disease: Analysis of Data From a Western Australian Quaternary Hospital Open
In patients admitted to the hospital with T2D and CKD, one-quarter were prescribed an SGLT2 inhibitor and/or a GLP-1 agonist at discharge. Further studies are required to identify barriers and enablers to prescribing these drugs.
View article: Clonal Haematopoiesis and Cardiovascular-Kidney-Metabolic Syndrome: Emerging Links
Clonal Haematopoiesis and Cardiovascular-Kidney-Metabolic Syndrome: Emerging Links Open
View article: MRI assessed cardiac structure and function in young adult offspring of hypertensive pregnancies: a 27-year prospective follow-up birth cohort
MRI assessed cardiac structure and function in young adult offspring of hypertensive pregnancies: a 27-year prospective follow-up birth cohort Open
This study is the largest prospective cardiac magnetic resonance study to assess clinical and subclinical changes in young adult offspring of hypertensive pregnancy. No significant adverse changes in cardiac structure and function were obs…
View article: Chromosome-level genome assembly of the autotetraploid yellow pitaya provides novel insights into evolution of trait patterning in pitaya species with different ploidy
Chromosome-level genome assembly of the autotetraploid yellow pitaya provides novel insights into evolution of trait patterning in pitaya species with different ploidy Open
View article: MALDI-MSI reveals shared lipid signatures in sarcoid-like granulomas of mice and in a human case
MALDI-MSI reveals shared lipid signatures in sarcoid-like granulomas of mice and in a human case Open
This is the first study to apply MALDI-MSI to characterize the spatial lipidomic landscape of granulomatous inflammation in both a murine sarcoid-like model and a rare human case. Our work reveals distinct yet shared lipidomic profiles in …
View article: Cardiac Granulomatous Disease Following Silicone Breast Augmentation
Cardiac Granulomatous Disease Following Silicone Breast Augmentation Open
Cardiac sarcoidosis is a rare cause of symptomatic sinoatrial node dysfunction (SND). Silicone breast augmentation has been associated with various phenotypes of sarcoidosis, but not to our knowledge with cardiac involvement. We present a …
View article: Arteriovenous Sampling for Organ-Specific Metabolic Insights in CKM Syndrome
Arteriovenous Sampling for Organ-Specific Metabolic Insights in CKM Syndrome Open
Cardiovascular-kidney-metabolic (CKM) syndrome recognises connections among obesity, diabetes, chronic kidney disease, and cardiovascular disease, describing the close metabolic links and shared risk factors including dyslipidemia, hyperte…
View article: Fluorodeoxyglucose Positron Emission Tomography Detects Persistent Arterial Inflammation After Symptomatic COVID-19
Fluorodeoxyglucose Positron Emission Tomography Detects Persistent Arterial Inflammation After Symptomatic COVID-19 Open
Ongoing arterial inflammation is detected by FDG-PET imaging after mild-to-moderate COVID-19. Larger prospective studies are needed to assess the implications on CVD risk.
View article: Inflammatory and vascular biomarkers as predictors of all‐cause death and cardiovascular outcomes in an Australian community‐based cohort
Inflammatory and vascular biomarkers as predictors of all‐cause death and cardiovascular outcomes in an Australian community‐based cohort Open
Biomarkers that identify individuals who are at higher risk of cardiovascular outcomes will allow for early intervention, lowering the incidence of adverse outcomes. This study investigated whether circulating levels of GDF‐15, E‐selectin,…
View article: The combined impact of chronic kidney disease and ulcer severity on incident cardiovascular events in patients with diabetes‐related foot ulceration
The combined impact of chronic kidney disease and ulcer severity on incident cardiovascular events in patients with diabetes‐related foot ulceration Open
In patients with diabetes‐related foot ulceration (DFU), ulcer severity and chronic kidney disease (CKD) portend worse outcomes. We evaluated the combined impact of a severe ulcer with CKD on major adverse cardiovascular events (MACE) in p…
View article: A feasibility study on non-invasive and non-contact jugular venous pulse measurement using 60 GHz FMCW radar
A feasibility study on non-invasive and non-contact jugular venous pulse measurement using 60 GHz FMCW radar Open
The jugular venous pulse (JVP) reflects right atrial pressure and provides diagnostic insight into cardiovascular and pulmonary health. However, reliable assessment remains difficult due to neck adiposity, anatomical variability and subopt…
View article: Achievement of low-density lipoprotein cholesterol goals in patients with diabetes-related foot ulceration
Achievement of low-density lipoprotein cholesterol goals in patients with diabetes-related foot ulceration Open
Despite their elevated risk for cardiovascular complications, two-thirds of patients with diabetes-related foot ulceration in this contemporary real-world study were not achieving guideline-recommended goals for low-density lipoprotein cho…
View article: Eligibility for Semaglutide 2.4 mg in Patients With Acute Myocardial Infarction and Overweight or Obesity Without Diabetes: A Real-World Analysis
Eligibility for Semaglutide 2.4 mg in Patients With Acute Myocardial Infarction and Overweight or Obesity Without Diabetes: A Real-World Analysis Open
View article: Interventions to prevent or treat obesity in adult Indigenous Australians: A systematic review
Interventions to prevent or treat obesity in adult Indigenous Australians: A systematic review Open
Community-based lifestyle interventions to manage excess weight can be successfully conducted in Indigenous Australians, but with generally limited efficacy. Providing background community-based lifestyle programs may facilitate the conduc…
View article: A Genetic Test to Identify People at High Risk of Heart Failure
A Genetic Test to Identify People at High Risk of Heart Failure Open
Earlier intervention may delay or prevent heart failure (HF), a widespread health problem. However, it is not currently possible to identify those who are most at risk, especially before the appearance of any clinical signs. This study pre…
View article: Evaluation of tissue-specific extraction protocols for comprehensive lipid profiling
Evaluation of tissue-specific extraction protocols for comprehensive lipid profiling Open
This study presents a new approach to studying lipid profiles derived from diverse tissues that substantially improve comprehensive lipid species' detection sensitivity and reliability. Our systematic evaluation provides evidence that tail…
View article: Learnings from Implementation Strategies to Improve Lipid Management
Learnings from Implementation Strategies to Improve Lipid Management Open
View article: Regeneration of Damaged Facial Images Using Generative Ai
Regeneration of Damaged Facial Images Using Generative Ai Open
View article: Unravelling the cardio-renal-metabolic-foot connection in people with diabetes-related foot ulceration: a narrative review
Unravelling the cardio-renal-metabolic-foot connection in people with diabetes-related foot ulceration: a narrative review Open
View article: Comparing predictive risk to actual presence of coronary atherosclerosis on coronary computed tomography angiography
Comparing predictive risk to actual presence of coronary atherosclerosis on coronary computed tomography angiography Open
In asymptomatic individuals without known CAD, a low CVRS does not exclude extensive CAD. Newer tools incorporating additional markers may be helpful in risk prediction in such individuals.
View article: Increased risk of major adverse cardiovascular events in patients with deep and infected diabetes-related foot ulcers
Increased risk of major adverse cardiovascular events in patients with deep and infected diabetes-related foot ulcers Open
View article: Beyond Clinical Factors: Harnessing Artificial Intelligence and Multimodal Cardiac Imaging to Predict Atrial Fibrillation Recurrence Post-Catheter Ablation
Beyond Clinical Factors: Harnessing Artificial Intelligence and Multimodal Cardiac Imaging to Predict Atrial Fibrillation Recurrence Post-Catheter Ablation Open
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia, with catheter ablation being a key alternative to medical treatment for restoring normal sinus rhythm. Despite advances in understanding AF pathogenesis, approximately…
View article: Clinical outcomes and coronary artery lesion characteristics of young patients with ST elevation myocardial infarction and no standard modifiable risk factors
Clinical outcomes and coronary artery lesion characteristics of young patients with ST elevation myocardial infarction and no standard modifiable risk factors Open
Background Among ST‐elevation myocardial infarction (STEMI) patients, those with no standard modifiable risk factors (SMuRFs: hypertension, diabetes mellitus, hypercholesterolemia, and smoking) have higher 30‐day mortality than those with …
View article: Essentials for AI Research in Cardiology: Challenges and Mitigations
Essentials for AI Research in Cardiology: Challenges and Mitigations Open
View article: Ethical Challenges and Opportunities in Applying Artificial Intelligence to Cardiovascular Medicine
Ethical Challenges and Opportunities in Applying Artificial Intelligence to Cardiovascular Medicine Open
Much anticipation surrounds artificial intelligence's (AI) emergence as a promising tool in health care. It offers potential to revolutionise clinical practice through assistive and autonomous operation. The high prevalence of cardiac dise…
View article: Use of Artificial Intelligence Including Multimodal Systems to Improve the Management of Cardiovascular Disease
Use of Artificial Intelligence Including Multimodal Systems to Improve the Management of Cardiovascular Disease Open
The rising prevalence of cardiovascular disease presents an escalating challenge for current health services, which are grappling with increasing demands. Innovative changes are imperative to sustain the delivery of high-quality patient ca…
View article: Chromosome-level genome assembly of autotetraploid<i>Selenicereus megalanthus</i>and gaining genomic insights into the evolution of trait patterning in diploid and polyploid pitaya species
Chromosome-level genome assembly of autotetraploid<i>Selenicereus megalanthus</i>and gaining genomic insights into the evolution of trait patterning in diploid and polyploid pitaya species Open
Yellow pitaya ( Selenicereus megalanthus , 2n=4x=44) breeding remains severely hindered due to lacking a reference genome. Here we report yellow pitaya’s high-quality chromosome-level genome assembly and link the phenotypic trait with geno…