S. E. Olkin
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View article: Does a Polycistronic 2A Design Enable Functional FcRn Production for Antibody Pharmacokinetic Studies?
Does a Polycistronic 2A Design Enable Functional FcRn Production for Antibody Pharmacokinetic Studies? Open
Background/Objectives: The neonatal Fc receptor (FcRn) is a heterodimeric protein composed of a heavy α-chain with an MHC class I-like fold and β2-microglobulin. It plays a crucial role in maintaining the homeostasis and pharmacokinetics o…
View article: Delta-Vac’ subunit vaccine induces strong humoral immune response against SARS-CoV-2
Delta-Vac’ subunit vaccine induces strong humoral immune response against SARS-CoV-2 Open
The COVID-19 pandemic has focused the worldwide attention on the fight against this infection. Development of preventive vaccines based on different platforms, including DNA and RNA vaccines, genetic vectors and subunit vaccines A has been…
View article: Structural Features of Nucleoproteins from the Recently Discovered Orthonairovirus songlingense and Norwavirus beijiense
Structural Features of Nucleoproteins from the Recently Discovered Orthonairovirus songlingense and Norwavirus beijiense Open
The recent discovery of Orthonairovirus songlingense (SGLV) and Norwavirus beijiense (BJNV) in China has raised significant concern due to their potential to cause severe human disease. However, little is known about the structural feature…
View article: Antigenic features of the strains SARS-CoV-2 of omicron sublines assessed by hyperimmune mouse serum neutralisation
Antigenic features of the strains SARS-CoV-2 of omicron sublines assessed by hyperimmune mouse serum neutralisation Open
Introduction. The emergence and spread of new genetic variants of SARS-CoV-2 underlies periodic upsurge in COVID-19 incidence. It has been shown that the most rapidly spreading genetic variants of SARS-CoV-2 are resistant to antibodies spe…
View article: Three-Year Monitoring of Microorganisms’ Composition and Concentration in Atmospheric Aerosols of Novosibirsk City and Suburbs
Three-Year Monitoring of Microorganisms’ Composition and Concentration in Atmospheric Aerosols of Novosibirsk City and Suburbs Open
The atmospheric environment is formed under the influence of local and distant sources as a result of horizontal and vertical transport. In the present work, microbiological analysis of 604 samples of atmospheric aerosol collected in the p…
View article: Evaluation of humoral immune responses of experimental animals to the recombinant SARS-CoV-2 spike ectodomain with the ISCOM adjuvant
Evaluation of humoral immune responses of experimental animals to the recombinant SARS-CoV-2 spike ectodomain with the ISCOM adjuvant Open
Scientific relevance . The use of recombinant antigens in vaccine production is limited because vaccines based on such antigens tend to have low immunogenicity. However, a COVID-19 vaccine that combines recombinant SARS-CoV-2 spike glycopr…
View article: Composition and Concentration of the Biogenic Components of the Aerosols Collected over Vasyugan Marshes and Karakan Pine Forest at Altitudes from 500 to 7000 m
Composition and Concentration of the Biogenic Components of the Aerosols Collected over Vasyugan Marshes and Karakan Pine Forest at Altitudes from 500 to 7000 m Open
The purpose of this study was to compare the concentration of total protein, as well as the composition and abundance of culturable microorganisms in atmospheric aerosols collected over the Vasyugan marshes and the Karakan pine forest duri…
View article: Integrated airborne investigation of the air composition over the Russian sector of the Arctic
Integrated airborne investigation of the air composition over the Russian sector of the Arctic Open
The change of the global climate is most pronounced in the Arctic, where the air temperature increases 2 to 3 times faster than the global average. This process is associated with an increase in the concentration of greenhouse gases in the…
View article: Long-Term Studies of Biological Components of Atmospheric Aerosol: Trends and Variability
Long-Term Studies of Biological Components of Atmospheric Aerosol: Trends and Variability Open
Background: Biological components of atmospheric aerosol affect the quality of atmospheric air. Long-term trends in changes of the concentrations of total protein (a universal marker of the biogenic component of atmospheric aerosol) and cu…
View article: Integrated airborne investigation of the air composition over the Russian Sector of the Arctic
Integrated airborne investigation of the air composition over the Russian Sector of the Arctic Open
The change of the global climate is most pronounced in the Arctic, where the air temperature increases two to three times faster than the global average. This process is associated with an increase in the concentration of greenhouse gases …
View article: How Has the Hazard to Humans of Microorganisms Found in Atmospheric Aerosol in the South of Western Siberia Changed over 10 Years?
How Has the Hazard to Humans of Microorganisms Found in Atmospheric Aerosol in the South of Western Siberia Changed over 10 Years? Open
One of the most important components of atmospheric aerosols are microorganisms. Therefore, it is necessary to assess the hazard to humans, both from individual microorganisms which are present in atmospheric bioaerosols as well as from th…
View article: CULTURABLE MICROORGANISMS IN HIGH-ALTITUDE ATMOSPHERIC AEROSOL SAMPLES COLLECTED ABOVE NORTHERN SIBERIA BY AIRCRAFT SOUNDING
CULTURABLE MICROORGANISMS IN HIGH-ALTITUDE ATMOSPHERIC AEROSOL SAMPLES COLLECTED ABOVE NORTHERN SIBERIA BY AIRCRAFT SOUNDING Open
To contribute to the comprehensive study of atmospheric pollution in Siberia, aircraft soundingwas carried out in Northwestern Siberian along the following route: Novosibirsk - Surgut - Igarka - Novosibirsk. This work was aimed at studying…