Evan S. Schwarz
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View article: Disparities in Treatment and Referral After an Opioid Overdose Among Emergency Department Patients
Disparities in Treatment and Referral After an Opioid Overdose Among Emergency Department Patients Open
Importance There is a disproportionately high rate of overdose deaths immediately following an emergency department (ED) visit for opioid overdose. Thus, an improved understanding of disparities in ED treatment and referral is vital. Racia…
View article: Emergency department management of opioid use disorder in pediatric patients
Emergency department management of opioid use disorder in pediatric patients Open
Opioid use disorder (OUD) has emerged as a significant public health crisis affecting individuals across all age groups. However, there remains a critical gap in understanding the specific nuances and challenges associated with OUD in pedi…
View article: Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE‐4): Alcohol use disorder and cannabinoid hyperemesis syndrome management in the emergency department
Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE‐4): Alcohol use disorder and cannabinoid hyperemesis syndrome management in the emergency department Open
The fourth Society for Academic Emergency Medicine (SAEM) Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE‐4) is on the topic of the emergency department (ED) management of nonopioid use disorders and focus…
View article: Acute opioid overdose in pediatric patients
Acute opioid overdose in pediatric patients Open
Recent increases in pediatric and adolescent opioid fatalities mandate an urgent need for early consideration of possible opioid exposure and specific diagnostic and management strategies and interventions tailored to these unique populati…
View article: Naloxone Use in Novel Potent Opioid and Fentanyl Overdoses in Emergency Department Patients
Naloxone Use in Novel Potent Opioid and Fentanyl Overdoses in Emergency Department Patients Open
Importance Synthetic opioids, such as the fentanyl analogue and nitazene drug class, are among the fastest growing types of opioids being detected in patients in the emergency department (ED) with illicit opioid overdose (OD). However, cli…
View article: Lipid emulsion therapy during management of the critically-ill poisoned patient: a prospective cohort study
Lipid emulsion therapy during management of the critically-ill poisoned patient: a prospective cohort study Open
Despite conflicting data, intravenous lipid emulsion has emerged as a potential antidote. The “lipid sink” theory suggests that following intravenous administration of lipid, lipophilic drugs are sequestered in the vascular compartment, th…
View article: Delayed-onset Angioedema Following a Snakebite in a Patient on ACE Inhibitors: A Case Report
Delayed-onset Angioedema Following a Snakebite in a Patient on ACE Inhibitors: A Case Report Open
Introduction: Angiotensin converting enzyme inhibitors (ACEI) are a common class of medications prescribed to patients for hypertension. Anti-hypertensive use is not normally considered an important factor when treating patients with crota…
View article: Opioid overdoses involving xylazine in emergency department patients: a multicenter study
Opioid overdoses involving xylazine in emergency department patients: a multicenter study Open
In this large multicenter cohort, cardiac arrest and coma in emergency department patients with illicit opioid overdose were significantly less severe in those testing positive for xylazine.
View article: Medications for Opioid Use Disorder Do Help Patients.
Medications for Opioid Use Disorder Do Help Patients. Open
Much of the focus on the current opioid crisis remains on how we arrived here and who is to blame. Despite having effective treatments for the management of patients with opioid use disorder (OUD), rates of overdose deaths continue to incr…
View article: Patients With Serious Injection Drug Use–Related Infections who Experience Patient-Directed Discharges on Oral Antibiotics Have High Rates of Antibiotic Adherence but Require Multidisciplinary Outpatient Support for Retention in Care
Patients With Serious Injection Drug Use–Related Infections who Experience Patient-Directed Discharges on Oral Antibiotics Have High Rates of Antibiotic Adherence but Require Multidisciplinary Outpatient Support for Retention in Care Open
Background Persons who inject drugs (PWID) are frequently admitted for serious injection-related infections (SIRIs). Outcomes and adherence to oral antibiotics for PWID with patient-directed discharge (PDD) remain understudied. Methods We …
View article: Value of Packaged Testing for Sexually Transmitted Infections for Persons who Inject Drugs Hospitalized With Serious Injection-Related Infections
Value of Packaged Testing for Sexually Transmitted Infections for Persons who Inject Drugs Hospitalized With Serious Injection-Related Infections Open
Background Persons who inject drugs (PWID) are frequently admitted for serious injection-related infections (SIRIs). PWID are also at risk for sexually transmitted infections (STIs). Methods We conducted a multicenter quality improvement p…
View article: Care cascade for patients with opioid use disorder and serious injection related infections
Care cascade for patients with opioid use disorder and serious injection related infections Open
An OUD care cascade evaluation for patients with SIRI demonstrated that referral to peer recovery services with outpatient OUD treatment was associated with reduced 90-day readmission rate.
View article: <i>N</i>‐acetylcysteine for acetaminophen toxicity: The one‐bag regimen
<i>N</i>‐acetylcysteine for acetaminophen toxicity: The one‐bag regimen Open
We read with interest the recent commentary by Isbister and Chiew1 reviewing recent developments in the use of N-acetylcysteine (NAC) for the treatment of acetaminophen (APAP) toxicity. While we appreciate the authors' clear and succinct r…