Sanjay Goel
YOU?
Author Swipe
View article: Multi-omic characterization of early-onset esophagogastric cancer
Multi-omic characterization of early-onset esophagogastric cancer Open
Using a large real-world database with matched genomic and transcriptomic data, we characterized clinical and molecular differences between patients with early-onset esophagogastric cancer (EOEGC; 65 years). We analyzed clinicopathologic, …
View article: Crime Survivors Rehabilitation Program in Delhi: An Analysis
Crime Survivors Rehabilitation Program in Delhi: An Analysis Open
This article undertakes a critical assessment of the Victim Rehabilitation Programme for the State of Delhi, by examining the framework within the broader context of Section 357A of the Code of Criminal Procedure, 1973 now Section 396 Bhar…
View article: AI-Driven Energy Management in Green Cloud Computing: A Systematic Review
AI-Driven Energy Management in Green Cloud Computing: A Systematic Review Open
The rapid expansion of cloud computing has significantly increased energy consumption, now accounting for an estimated 2–4% of global carbon dioxide emissions (Jones, 2023). In response, Artificial Intelligence (AI) has become a vital enab…
View article: Modulating autophagy in KRAS mutant colorectal cancer using combination of oncolytic reovirus and carbamazepine
Modulating autophagy in KRAS mutant colorectal cancer using combination of oncolytic reovirus and carbamazepine Open
Oncolytic reovirus is a potential therapeutic for colorectal cancer patients with a mutant KRAS gene. Reovirus hijacks the autophagic machinery and preferentially induces apoptosis in patients with a KRAS mutation. However, reovirus on its…
View article: Infectious Agents and Esophageal Cancer: A Comprehensive Review
Infectious Agents and Esophageal Cancer: A Comprehensive Review Open
Esophageal cancer, primarily comprising the squamous cell carcinoma (ESCC) and adenocarcinoma (EAC) subtypes, is the sixth leading cause of cancer deaths globally. In addition to many well-established endogenous and exogenous risk factors,…
View article: Secure Generalization through Stochastic Bidirectional Parameter Updates Using Dual-Gradient Mechanism
Secure Generalization through Stochastic Bidirectional Parameter Updates Using Dual-Gradient Mechanism Open
Federated learning (FL) has gained increasing attention due to privacy-preserving collaborative training on decentralized clients, mitigating the need to upload sensitive data to a central server directly. Nonetheless, recent research has …
View article: Supplementary Table S3 from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma
Supplementary Table S3 from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma Open
Supplementary Table S3: Comparison of MPAS gene expression between KRAS mutational subgroups. Median values represent transcript per million (TPM). Only genes with trending or significant differences between subgroups are shown. Bold numbe…
View article: Supplementary Table S2 from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma
Supplementary Table S2 from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma Open
Supplementary Table S2: Comparison of TP53 and CDKN2A genomic alterations between KRAS G12R and G12D subgroups.
View article: Supplementary Table S4 from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma
Supplementary Table S4 from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma Open
Supplementary Table S4: Comparison of cytokine gene expression between KRAS mutational subgroups. Median values represent transcript per million (TPM). Only genes with trending or significant differences between subgroups are shown. Bold n…
View article: Supplementary Table S5 from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma
Supplementary Table S5 from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma Open
Supplementary Table S5: GSEA analysis comparing enrichment of gene expression pathways in G12R compared to G12D cohorts. Negative enrichment score (es) indicates lower enrichment in G12R.
View article: Data from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma
Data from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma Open
Purpose:Oncogenic mutations in KRAS have been identified in >85% of pancreatic ductal adenocarcinoma (PDAC) cases, with G12D, G12V, and G12R being the most frequent variants. Using large clinical and genomic databases, this study character…
View article: Supplementary Table S1 from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma
Supplementary Table S1 from Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma Open
Supplementary Table S1: Comparison of genomic alterations between KRAS G12R and G12D subgroups related to the PI3K/AKT/MTOR pathway.
View article: Identifying distinct prognostic and predictive contributions of tumor epithelium versus tumor microenvironment in colorectal cancer
Identifying distinct prognostic and predictive contributions of tumor epithelium versus tumor microenvironment in colorectal cancer Open
Here we identified a pair of new, distinct 10-gene signatures (the EPIS vs. the TMES) capable of distinguishing the cellular contribution of the tumor EPI vs. the TME in determining CRC prognosis and therapeutic outcomes. With targeted app…
View article: Molecular Characterization and Clinical Outcomes of Pancreatic Neuroendocrine Neoplasms Harboring PAK4-NAMPT Alterations
Molecular Characterization and Clinical Outcomes of Pancreatic Neuroendocrine Neoplasms Harboring PAK4-NAMPT Alterations Open
PURPOSE The mammalian target of rapamycin (mTOR) inhibitor everolimus is US Food and Drug Administration-approved for advanced pancreatic neuroendocrine neoplasms (pNENs), yet resistance is common, necessitating the identification of resis…
View article: Pruning as a Defense: Reducing Memorization in Large Language Models
Pruning as a Defense: Reducing Memorization in Large Language Models Open
Large language models have been shown to memorize significant portions of their training data, which they can reproduce when appropriately prompted. This work investigates the impact of simple pruning techniques on this behavior. Our findi…
View article: Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma
Distinct Molecular and Clinical Features of Specific Variants of KRAS Codon 12 in Pancreatic Adenocarcinoma Open
Purpose: Oncogenic mutations in KRAS have been identified in >85% of pancreatic ductal adenocarcinoma (PDAC) cases, with G12D, G12V, and G12R being the most frequent variants. Using large clinical and genomic databases, this study chara…
View article: Comprehensive characterization of <i>MCL‐1</i> in patients with colorectal cancer: Expression, molecular profiles, and outcomes
Comprehensive characterization of <i>MCL‐1</i> in patients with colorectal cancer: Expression, molecular profiles, and outcomes Open
Myeloid cell leukemia 1 (MCL‐1) is a member of the B‐cell lymphoma 2 protein family and has anti‐apoptotic functions. Deregulation of MCL‐1 has been reported in several cancers, including lung and breast cancer. In the present study, the a…
View article: Big Data Methods and Analytics for Text, Audio, Video, and Social Media Data Concepts: Methods and Analytics for Text, Audio, Video, and Social Media Data
Big Data Methods and Analytics for Text, Audio, Video, and Social Media Data Concepts: Methods and Analytics for Text, Audio, Video, and Social Media Data Open
This paper provides a unified description of big data by integrating ideas from academics and practitioners. The primary focus of the paper is the analytical methods applied to big data. The focus this study places on analytics for unstruc…
View article: Sitravatinib in patients with solid tumors selected by molecular alterations: results from a Phase Ib study
Sitravatinib in patients with solid tumors selected by molecular alterations: results from a Phase Ib study Open
Aim: We report clinical activity and safety of sitravatinib in patients with advanced cancer from basket cohorts with specific molecular alterations, in a Phase Ib study.Materials & methods: Patients with advanced solid tumors harboring am…
View article: Supplementary Table 6 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer
Supplementary Table 6 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer Open
Supplementary Table 6
View article: Supplementary Table 2 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer
Supplementary Table 2 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer Open
Supplementary Table 2
View article: Supplementary Table 4 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer
Supplementary Table 4 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer Open
Supplementary Table 4
View article: Supplementary Table 5 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer
Supplementary Table 5 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer Open
Supplementary Table 5
View article: Supplementary Table 9 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer
Supplementary Table 9 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer Open
Supplementary Table 9
View article: Supplementary Table 7 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer
Supplementary Table 7 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer Open
Supplementary Table 7
View article: Supplementary Table 8 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer
Supplementary Table 8 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer Open
Supplementary Table 8
View article: Supplementary Table 10 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer
Supplementary Table 10 from Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer Open
Supplementary Table 10