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Complement C3a-C3aR signaling in the colon epithelium 4117 Open
Description The liver-derived complement system has been considered the body’s main source for the complement cascade. Recently, complement C3 was found to be expressed in the gut under steady-state conditions and during inflammatory condi…
Colonic epithelial exposure to heavy metals results in a chemokine response to recruit monocytes and macrophages 4306 Open
Description Background The intestinal epithelium and lamina propria immune system must work in concert to respond to luminal cues, infection or injury to maintain intestinal homeostasis. One example is the recruitment of immune cells to th…
Colonic epithelial exposure to heavy metals results in a chemokine response to recruit monocytes and macrophages 4306 Open
Description Background The intestinal epithelium and lamina propria immune system must work in concert to respond to luminal cues, infection or injury to maintain intestinal homeostasis. One example is the recruitment of immune cells to th…
Metabolomic, Lipidomic, and Enterohormone Changes in the Progression from MASLD to MASH Open
Background & Aims Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-Associated Steatohepatitis (MASH) represent progressive stages of liver disease, with distinct metabolic and cellular alterations.…
View article: Gestational ozone inhalation elicits maternal cardiac dysfunction and transcriptional changes to placental pericytes and endothelial cells
Gestational ozone inhalation elicits maternal cardiac dysfunction and transcriptional changes to placental pericytes and endothelial cells Open
Ozone (O3) is a criteria air pollutant with the most frequent incidence of exceeding air quality standards. Inhalation of O3 is known to cause lung inflammation and consequent systemic health effects, including endothelial dysfunction. Epi…