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View article: Central retinal volume derived from optical coherence tomography as a potential predictor of mortality in the old-aged population– results from the German AugUR study
Central retinal volume derived from optical coherence tomography as a potential predictor of mortality in the old-aged population– results from the German AugUR study Open
Purpose To estimate mortality risk depending on central retinal volume (CRV) from optical coherence tomography (OCT) in a German cohort of the old-aged population. Methods In the AugUR study, a prospective population-based cohort study in …
View article: Management of macula-on giant retinal tear detachments– outcome of pars-plana-vitrectomy with silicone oil versus gas tamponade
Management of macula-on giant retinal tear detachments– outcome of pars-plana-vitrectomy with silicone oil versus gas tamponade Open
Background To compare the outcome of eyes with a macula-on giant retinal tear (GRT) detachment treated with pars-plana-vitrectomy (PPV) depending on the used endotamponade. Methods All consecutive cases with a macula-on GRT-associated rheg…
View article: A unique late-onset intraocular lens opacification 23 years after implantation: a clinical and laboratory case report
A unique late-onset intraocular lens opacification 23 years after implantation: a clinical and laboratory case report Open
We report an unusual, rare case of opacification of the hydrophilic acrylic intraocular lens (IOL) 23 years after the initial surgery with significant visual deterioration. Opacification of the hydrophilic acrylic IOL was primarily due to …
View article: Baseline characteristics and progression of neovascular age-related macular degeneration in patients receiving over 60 intravitreal injections of anti-vascular endothelial growth factor
Baseline characteristics and progression of neovascular age-related macular degeneration in patients receiving over 60 intravitreal injections of anti-vascular endothelial growth factor Open
Objective: Age-related macular degeneration (AMD) is the leading cause of vision loss in older populations of industrialized countries. Antibody-based therapy inhibiting the vascular endothelial growth factor (VEGF) has been very successfu…
View article: Long-Term Outcome and Complications of IOL-Exchange
Long-Term Outcome and Complications of IOL-Exchange Open
Purpose: To describe the long-term outcome after intraocular lens (IOL) exchange for IOL-opacification with a focus on any occurring complications. Patients and Methods: Patients with an IOL exchange for opacified IOLs (Lentis LS-502-1) we…
View article: Genetic Risk Score Analysis Supports a Joint View of Two Classification Systems for Age-Related Macular Degeneration
Genetic Risk Score Analysis Supports a Joint View of Two Classification Systems for Age-Related Macular Degeneration Open
PURPOSE. The purpose of this study was to evaluate the utility of combining the Clinical Classification (CC) and the Three Continent age-related macular degeneration (AMD) Consortium Severity Scale (3CACSS) for classification of AMD. METHO…
View article: Photostress Recovery Time as a Potential Predictive Biomarker for Age-Related Macular Degeneration
Photostress Recovery Time as a Potential Predictive Biomarker for Age-Related Macular Degeneration Open
Purpose: The purpose of this study was to assess recovery time following photostress and its association with age-related macular degeneration (AMD) cross-sectionally and longitudinally in an elderly population-based cohort. Methods: We an…
View article: Assessment of Retinopathy of Prematurity Regression and Reactivation Using an Artificial Intelligence–Based Vascular Severity Score
Assessment of Retinopathy of Prematurity Regression and Reactivation Using an Artificial Intelligence–Based Vascular Severity Score Open
Importance One of the biggest challenges when using anti–vascular endothelial growth factor (VEGF) agents to treat retinopathy of prematurity (ROP) is the need to perform long-term follow-up examinations to identify eyes at risk of ROP rea…
View article: Characteristics of Bilateral Retinal Detachment
Characteristics of Bilateral Retinal Detachment Open
Introduction: Rhegmatogenous retinal detachment (RD) is still a sight-threatening and potentially blinding disease, especially if both eyes are affected. The purpose of this study is analysing the specific characteristics of bilateral rheg…
View article: Opacified lens exchange – complications
Opacified lens exchange – complications Open
Purpose To describe the long-term outcome after intraocular lens exchange with focus on visual recovery and any occurring serious complications. Methods : Patients with a Lentis LS-502-1 IOL implanted between February 2008 and March 2012 w…
View article: Intravitreal 5-Fluorouracil and Heparin to Prevent Proliferative Vitreoretinopathy
Intravitreal 5-Fluorouracil and Heparin to Prevent Proliferative Vitreoretinopathy Open
Rate of PVR did not differ between adjuvant therapy with 5-FU and LMWH and placebo treatment in eyes with RRD.
View article: Rhegmatogenous retinal detachment repair—does age, sex, and lens status make a difference?
Rhegmatogenous retinal detachment repair—does age, sex, and lens status make a difference? Open
Purpose To analyze the correlation between lens status, age, and sex in the epidemiology and success rates of rhegmatogenous retinal detachment (RRD) surgery. Methods The files of all consecutive patients undergoing vitreoretinal surgery f…
View article: Incidence, progression and risk factors of age-related macular degeneration in 35–95-year-old individuals from three jointly designed German cohort studies
Incidence, progression and risk factors of age-related macular degeneration in 35–95-year-old individuals from three jointly designed German cohort studies Open
Objective To estimate age-related macular degeneration (AMD) incidence/progression across a wide age range. Methods and analysis AMD at baseline and follow-up (colour fundus imaging, Three Continent AMD Consortium Severity Scale, 3CACSS, c…
View article: The learning curve of retinal detachment surgery
The learning curve of retinal detachment surgery Open
Purpose To investigate the learning curve of vitreoretinal (VR) surgeons beginning training in retinal detachment (RD) surgery. Methods The files of all consecutive patients undergoing VR surgery for uncomplicated RD between Jan 2005 und M…
View article: Intravitreal anti-VEGF treatment for choroidal neovascularization secondary to traumatic choroidal rupture
Intravitreal anti-VEGF treatment for choroidal neovascularization secondary to traumatic choroidal rupture Open
Background So far only single cases with short follow-up have been reported on the use of intravitreal anti-VEGF for traumatic choroidal neovascularizations (CNV). This paper reports a large case series of patients with CNV secondary to ch…
View article: Retinal Layer Thicknesses in Early Age-Related Macular Degeneration: Results From the German AugUR Study
Retinal Layer Thicknesses in Early Age-Related Macular Degeneration: Results From the German AugUR Study Open
This first population-based study on spectral-domain optical coherence tomography-derived retinal layer thicknesses in a total of ∼1000 individuals provides insights into the reliability of autosegmentation and layer-specific reference val…
View article: Successful treatment of Fusarium solani anterior chamber involvement secondary to contact lens associated corneal ulcer with intracameral Amphotericin B
Successful treatment of Fusarium solani anterior chamber involvement secondary to contact lens associated corneal ulcer with intracameral Amphotericin B Open
Background:Fusarium spp. are leading fungal pathogenes in contact lens associated keratitis and may evoke endophthalmitis. Since Fusarium spp. are highly resistant to antifungal drugs, globe integrity is threatened. Case: A woman developed…
View article: Views of ophthalmologists on the genetics of age-related macular degeneration: Results of a qualitative study
Views of ophthalmologists on the genetics of age-related macular degeneration: Results of a qualitative study Open
Background Age-related macular degeneration (AMD) is the leading cause of blindness in industrialized countries. It is a multifactorial disease of the retina modified by environmental/individual (e.g. smoking) and genetic factors. 34 indep…
View article: Macular hole surgery: an analysis of risk factors for the anatomical and functional outcomes with a special emphasis on the experience of the surgeon
Macular hole surgery: an analysis of risk factors for the anatomical and functional outcomes with a special emphasis on the experience of the surgeon Open
Our results indicate that vitrectomy with ILM peeling performed by non-experienced surgeons is a safe procedure leading to good anatomical and functional results. Very experienced surgeons may achieve even better functional outcomes.
View article: Macular hole surgery: an analysis of risk factors for the anatomical outcome with special emphasis on the experience of the surgeon
Macular hole surgery: an analysis of risk factors for the anatomical outcome with special emphasis on the experience of the surgeon Open
Purpose: The aim of this study was to evaluate risk factors for the anatomical and functional outcomes of macular hole (MH) surgery with special emphasis on the experience of the surgeon. Methods: A total of 225 surgeries on idiopathic MHs…
View article: Features of Age-Related Macular Degeneration in the General Adults and Their Dependency on Age, Sex, and Smoking: Results from the German KORA Study
Features of Age-Related Macular Degeneration in the General Adults and Their Dependency on Age, Sex, and Smoking: Results from the German KORA Study Open
Age-related macular degeneration (AMD) is a vision impairing disease of the central retina characterized by early and late forms in individuals older than 50 years of age. However, there is little knowledge to what extent also younger adul…