Satoshi Kuroda
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Early Hematoma Evacuation Can Prevent Infectious Complications in Patients with Spontaneous Intracerebral Hemorrhage Open
Background/Objectives: Infections are common complications in patients with spontaneous intracerebral hemorrhage (ICH). This study investigated whether early surgical hematoma evacuation can reduce post-ICH infections and the impact of res…
External Validation on a Japanese Cohort of a Computer‐Aided Diagnosis System Aimed at Characterizing <span>ISUP</span> ≥ 2 Prostate Cancers at Multiparametric <span>MRI</span> Open
Objective To evaluate the generalizability of a computer‐aided diagnosis (CADx) system based on the apparent diffusion coefficient (ADC) and wash‐in rate, and trained on a French population to diagnose International Society of Urological P…
Infection Associated with Global Cerebral Edema and Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage Open
Background/Objectives: Patients with aneurysmal subarachnoid hemorrhage (SAH) experience functional impairment due to early brain injury and delayed complications. We aimed to clarify the association between cerebral edema and post-SAH inf…
Clinical and radiological profie changes of patients undergoing carotid endarterectomy over 40 years Open
Background This study aimed to explore how clinical and radiological profiles of patients undergoing carotid endarterectomy (CEA) have changed over the past 40 years. Methods We included our three Japanese case series of CEA in the late 19…
Treatment of Unruptured Large and Giant Carotid Cavernous Aneurysms in Japan at the Time of Flow Diverter Introduction: A Nationwide, Multicenter Survey by the Japanese Society on Surgery for Cerebral Stroke Open
The nationwide survey reported here determined the status of treatment for unruptured large/giant CCAs in Japan when FDs were being introduced. Because PAO has disadvantages including the long-term hemodynamic effects of ICA occlusion, rec…
Effect of Monosodium Urate Crystal Deposition on Atherosclerotic Carotid Plaques Open
Background/Objectives: The accumulation of uric acid in arteriosclerotic plaques has recently attracted attention. Because the interaction between hyperuricemia and atherosclerosis is complex, the details remain obscure. We aimed to elucid…
Evolutionary origins of synchronization for integrating information in neurons Open
The evolution of brain-expressed genes is notably slower than that of genes expressed in other tissues, a phenomenon likely due to high-level functional constraints. One such constraint might be the integration of information by neuron ass…
Accuracy of the Hounsfield Unit Values Measured by Implant Planning Software Open
Background: The measurement of Hounsfield units (HU) during implant treatment planning is important. Currently, various manufacturers’ implant planning software programs offer HU capabilities; however, their accuracy remains unverified. In…
Expression of <i>c-fos</i> in cortical neuron cultures under dynamic magnetic field is not suppressed by calcium channel blockers Open
Previously, we developed a dynamic magnetic field (DMF) device using neodymium magnets that induced c-fos expression in cortical neurons, while activity-regulated cytoskeleton-associated protein (Arc), and brain-derived neurotrophic factor…
The origins of light-independent magnetoreception in humans Open
The Earth’s abundance of iron has played a crucial role in both generating its geomagnetic field and contributing to the development of early life. In ancient oceans, iron ions, particularly around deep-sea hydrothermal vents, might have c…
View article: Diagnosis and management of adult Moyamoya angiopathy: An overview of guideline recommendations and identification of future research directions
Diagnosis and management of adult Moyamoya angiopathy: An overview of guideline recommendations and identification of future research directions Open
Despite the progress made in understanding the management and outcomes of Moyamoya angiopathy (MMA), several aspects of the disease remain largely unknown. In particular, evidence on the disease history and management of MMA is lacking, ma…
Association between Pericarotid Fat Density and Positive Remodeling in Patients with Carotid Artery Stenosis Open
Background/Objectives: The underlying mechanism of the potential involvement of inflammatory crosstalk between pericarotid fat and vascular layers in atherosclerosis pathogenesis is unclear. We investigated the association between pericaro…
Intraoperative monitoring of cerebrospinal fluid gas tension and pH before and after surgical revascularization for moyamoya disease Open
Background: This study aimed to directly measure cerebrospinal fluid (CSF) gas tensions and pH before and after superficial temporal artery to middle cerebral artery (STA-MCA) anastomosis for moyamoya disease. Methods: This study included …
Clinical Features, Radiological Findings, and Outcome in Patients with Symptomatic Mild (<50%) Carotid Stenosis: A MUSIC Study Open
Background and Purpose Plaque composition, but not stenosis degree, may play a key role in the development of recurrent ischemic events in patients with symptomatic, mild (<50%) carotid stenosis. This multi-center prospective cohort study …
View article: Stroke in Asia
Stroke in Asia Open
Background: There is a significant burden of stroke in Asia. Asia has the largest population in the world in 2023, estimated at 4.7 billion. Approximately 9.5–10.6 million strokes will be anticipated annually in the backdrop of a diverse g…
Resolution of white matter hyperintensity after surgical revascularization in moyamoya disease – A report of three cases Open
Background: Moyamoya disease often presents white matter hyperintensity (WMH) lesions on fluid-attenuated inversion recovery (FLAIR) images, which is generally accepted as irreversible. We, herein, describe three cases of moyamoya disease …
Evolutionary origin of alpha rhythms in vertebrates Open
The purpose of this review extends beyond the traditional triune brain model, aiming to elucidate the evolutionary aspects of alpha rhythms in vertebrates. The forebrain, comprising the telencephalon (pallium) and diencephalon (thalamus, h…
Diagnosis of a Dural Arteriovenous Fistula Involving the Superior Sagittal Sinus: The MMA Sign on Routine 3D-TOF MR Angiography Open
The MMA sign on routine MRA is useful, suggesting DAVF involving SSS.
Detection of Hyperdense Arterial Sign in Acute Ischemic Stroke with Dual-Energy Computed Tomography: Optimal Combination with X-ray Energy and Slice Thickness Open
Background: The hyperdense artery sign (HAS) in acute ischemic stroke (AIS) is considered an important marker of a thrombus on computed tomography (CT). An advantage of scanning with dual-energy CT (DECT) is its ability to reconstruct CT i…
Clinical Significance of Carotid Endarterectomy and Carotid Artery Stenting in Older Patients Over 80 Open
As the average life expectancy increases, neurosurgeons are likely to encounter patients aged 80 years and above with carotid stenosis; however, whether old age affects clinical post-treatment outcomes of carotid endarterectomy (CEA) or ca…
View article: Allogeneic Stem Cell Therapy for Acute Ischemic Stroke
Allogeneic Stem Cell Therapy for Acute Ischemic Stroke Open
Importance Cell therapy is a promising treatment approach for stroke and other diseases. However, it is unknown whether MultiStem (HLCM051), a bone marrow–derived, allogeneic, multipotent adult progenitor cell product, has the potential to…