Mir Sohail Fazeli
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View article: Prevalence and Incidence of Dilated Cardiomyopathy in the United States and Western Europe: A Systematic Review
Prevalence and Incidence of Dilated Cardiomyopathy in the United States and Western Europe: A Systematic Review Open
This study highlights the varied prevalence and incidence rates of DCM reported across different geographic locations, time periods, sexes, races, and disease definitions. When comparing these rates, it is crucial to consider factors such …
View article: Enhancing Online Learning Efficiency Through Heterogeneous Resource Integration with a Multi-Agent RAG System
Enhancing Online Learning Efficiency Through Heterogeneous Resource Integration with a Multi-Agent RAG System Open
Efficient online learning requires seamless access to diverse resources such as videos, code repositories, documentation, and general web content. This poster paper introduces early-stage work on a Multi-Agent Retrieval-Augmented Generatio…
View article: Diverse Concepts in Definitions of Dilated Cardiomyopathy: Theory and Practice
Diverse Concepts in Definitions of Dilated Cardiomyopathy: Theory and Practice Open
Our understanding of dilated cardiomyopathy (DCM) is evolving as new insights into the underlying pathophysiology become available. Professional organizations and clinical experts are improving definitions of DCM, allowing for more accurat…
View article: Immune checkpoint inhibitors in pediatric patients with melanoma: a systematic literature review
Immune checkpoint inhibitors in pediatric patients with melanoma: a systematic literature review Open
Aim: This study summarized the existing evidence on the outcomes and safety of anti-PD-1s, anti-PD-L1s and anti-CTLA-4s in pediatric patients with melanoma.Materials & methods: MEDLINE® and Embase were searched from database inception to 0…
View article: Prevalence of Genetically Associated Dilated Cardiomyopathy: A Systematic Literature Review and Meta-Analysis
Prevalence of Genetically Associated Dilated Cardiomyopathy: A Systematic Literature Review and Meta-Analysis Open
Our study identified variable prevalence estimates of genetic DCM across different populations and geographic locations. The current evidence may underestimate the genetic contributions due to limited screening and detection of potential D…
View article: Dronedarone versus sotalol in patients with atrial fibrillation: A systematic literature review and network meta‐analysis
Dronedarone versus sotalol in patients with atrial fibrillation: A systematic literature review and network meta‐analysis Open
Background There are limited comparative data on safety and efficacy within commonly used Vaughan‐Williams (VW) class III antiarrhythmic drugs (AADs) for maintenance of sinus rhythm in adults with atrial fibrillation (AF). Hypothesis We hy…
View article: Personality diversity in the workplace: A systematic literature review on introversion
Personality diversity in the workplace: A systematic literature review on introversion Open
Up to half of the population have introverted personalities. Workplace diversity can lead to increased productivity, creativity and problem-solving. Understanding introversion in relation to workplace performance and creativity and how to …
View article: Digital Devices for Assessing Motor Functions in Mobility-Impaired and Healthy Populations: Systematic Literature Review
Digital Devices for Assessing Motor Functions in Mobility-Impaired and Healthy Populations: Systematic Literature Review Open
Background With the advent of smart sensing technology, mobile and wearable devices can provide continuous and objective monitoring and assessment of motor function outcomes. Objective We aimed to describe the existing scientific literatur…
View article: Digital Devices for Assessing Motor Functions in Mobility Impaired and Healthy Populations: A Systematic Literature Review (Preprint)
Digital Devices for Assessing Motor Functions in Mobility Impaired and Healthy Populations: A Systematic Literature Review (Preprint) Open
BACKGROUND With the advent of smart sensing technology, mobile and wearable devices can provide continuous and objective monitoring and assessment of motor function outcomes. OBJECTIVE We aimed to describe the existing scientific litera…
View article: A fresh look at the role of spiramycin in preventing a neglected disease: meta-analyses of observational studies
A fresh look at the role of spiramycin in preventing a neglected disease: meta-analyses of observational studies Open
Purpose We aimed to investigate the effect of antepartum treatment with spiramycin with or without subsequent pyrimethamine–sulfonamide–folinic acid, compared to no treatment, on the rate of mother-to-child transmission (MTCT) of Toxoplasm…
View article: Cardiovascular Safety and Hemostatic Efficacy of Topical Epinephrine in Children Receiving Zirconia Crowns
Cardiovascular Safety and Hemostatic Efficacy of Topical Epinephrine in Children Receiving Zirconia Crowns Open
Objective: The primary aim of this study was to determine the cardiovascular safety of topical racemic epinephrine pellets by measuring heart rate, systolic blood pressure, diastolic blood pressure, and mean arterial pressure in children r…
View article: Rheumatoid arthritis-associated interstitial lung disease: epidemiology, risk/prognostic factors, and treatment landscape
Rheumatoid arthritis-associated interstitial lung disease: epidemiology, risk/prognostic factors, and treatment landscape Open
A wide range of estimates were identified for incidence and prevalence of RA-ILD. Further, there was no consensus on risk and prognostic factors. Sufficiently powered clinical trials are needed to confirm the findings of the observational …
View article: Health state utility values by cancer stage: a systematic literature review
Health state utility values by cancer stage: a systematic literature review Open
Objectives Cancer diagnoses at later stages are associated with a decrease in health-related quality of life (HRQOL). Health state utility values (HSUVs) reflect preference-based HRQOL and can vary based on cancer type, stage, treatment, a…
View article: Cardiovascular Disease in Rheumatoid Arthritis: Risk Factors, Autoantibodies, and the Effect of Antirheumatic Therapies
Cardiovascular Disease in Rheumatoid Arthritis: Risk Factors, Autoantibodies, and the Effect of Antirheumatic Therapies Open
Objective: To scope the current published evidence on cardiovascular risk factors in rheumatoid arthritis (RA) focusing on the role of autoantibodies and the effect of antirheumatic agents. Methods: Two reviews were conducted in parallel: …
View article: Efficacy and Safety of Antiplatelet Therapies in Symptomatic Peripheral Artery Disease: A Systematic Review and Network Meta-Analysis
Efficacy and Safety of Antiplatelet Therapies in Symptomatic Peripheral Artery Disease: A Systematic Review and Network Meta-Analysis Open
Background: Clopidogrel monotherapy is guideline-recommended in symptomatic peripheral artery disease (PAD). The advent of new antithrombotic strategies prompts an updated analysis of available evidence on antiplatelet therapy for PAD. Met…
View article: Efficacy and safety of <scp>iGlarLixi</scp> versus <scp>IDegLira</scp> in adults with type 2 diabetes inadequately controlled by glucagon‐like peptide‐1 receptor agonists: a systematic literature review and indirect treatment comparison
Efficacy and safety of <span>iGlarLixi</span> versus <span>IDegLira</span> in adults with type 2 diabetes inadequately controlled by glucagon‐like peptide‐1 receptor agonists: a systematic literature review and indirect treatment comparison Open
Aims To estimate the relative treatment effect between the fixed‐ratio combinations iGlarLixi and IDegLira (glucagon‐like peptide 1 receptor agonist with basal insulin) in people with type 2 diabetes inadequately controlled on a glucagon‐l…
View article: The Effect of Massage on the Cardiac Autonomic Nervous System and Markers of Inflammation in Night Shift Workers: a Pilot Randomized Crossover Trial
The Effect of Massage on the Cardiac Autonomic Nervous System and Markers of Inflammation in Night Shift Workers: a Pilot Randomized Crossover Trial Open
Background: Shift work is a necessary part of many industries; however, it can have detrimental effects on health over time.
Purpose: This study investigated the effect of a massage intervention on the cardiac autonomic activity and blood…