Sharmila Majumdar
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View article: Cartilage Compositional T <sub>2</sub> Patterns in Subjects at Risk of Polyarticular OA: Technical Feasibility at 0.55 T, Clinical and Functional Associations
Cartilage Compositional T <sub>2</sub> Patterns in Subjects at Risk of Polyarticular OA: Technical Feasibility at 0.55 T, Clinical and Functional Associations Open
The feasibility of rapid, state‐of‐the‐art, and quantitative T 2 ‐mapping at low field (0.55 T) MRI compared to 3.0 T and its associations with clinical and functional performance remain a crucial yet underexplored piece. A phantom of falc…
View article: Dr. Gensler et al reply
Dr. Gensler et al reply Open
View article: Exploratory analysis of infrapatellar fat pad MRI-based radiomics for detection of knee structure abnormalities in collegiate basketball players and swimmers
Exploratory analysis of infrapatellar fat pad MRI-based radiomics for detection of knee structure abnormalities in collegiate basketball players and swimmers Open
View article: Rapid and robust quantitative cartilage assessment for the clinical setting: deep learning-enhanced accelerated T2 mapping
Rapid and robust quantitative cartilage assessment for the clinical setting: deep learning-enhanced accelerated T2 mapping Open
Objective Clinical adoption of T2 mapping is limited by poor reproducibility, lengthy examination times, and cumbersome image analysis. This study aimed to develop an accelerated deep learning (DL)-enhanced cartilage T2 mapping sequence (D…
View article: Relationship Between Early Cartilage Degeneration With T1ρ and T2 Analysis in Medial Tibial Cartilage and 10-Year Posttraumatic Osteoarthritis Progression After ACL Reconstruction
Relationship Between Early Cartilage Degeneration With T1ρ and T2 Analysis in Medial Tibial Cartilage and 10-Year Posttraumatic Osteoarthritis Progression After ACL Reconstruction Open
Background: Quantitative magnetic resonance imaging (qMRI), such as T1ρ and T2 mapping, allows for the characterization of the biochemical composition of cartilage and the detection of early degeneration within 1 year after anterior crucia…
View article: Explainable AI reveals tissue pathology and psychosocial drivers of opioid prescription for non-specific chronic low back pain
Explainable AI reveals tissue pathology and psychosocial drivers of opioid prescription for non-specific chronic low back pain Open
Effective management of non-specific chronic lower back pain (ns-cLBP) requires nuanced prescription decisions within evolving guidelines for conservative treatment. This study developed comprehensive LBP patient profiles from electronic m…
View article: Foraminal [<sup>18</sup>F]FDG uptake on PET/MRI is associated with radiculopathy and symptom reduction after image-guided nerve root block
Foraminal [<sup>18</sup>F]FDG uptake on PET/MRI is associated with radiculopathy and symptom reduction after image-guided nerve root block Open
LBP = Low back pain, SUVmax = Maximum standardized uptake value.
View article: Baseline characteristics of participants in the Biomarkers for Evaluating Spine Treatments clinical trial: a sequential multiple assignment randomized trial for chronic low back pain
Baseline characteristics of participants in the Biomarkers for Evaluating Spine Treatments clinical trial: a sequential multiple assignment randomized trial for chronic low back pain Open
Objective Chronic low back pain (cLBP) is a significant public health problem in the United States. A method to identify treatments that are most likely effective for an individual patient based on their unique characteristics is needed. M…
View article: Machine learning models for clinical and structural knee osteoarthritis prediction: Recent advancements and future directions
Machine learning models for clinical and structural knee osteoarthritis prediction: Recent advancements and future directions Open
View article: A Cephalometric Study of the Adult Subjects Attending General Outpatient Department in North Bengal Medical College and Hospital in Relation to Sex and Racial Factors
A Cephalometric Study of the Adult Subjects Attending General Outpatient Department in North Bengal Medical College and Hospital in Relation to Sex and Racial Factors Open
This descriptive cross-sectional study was conducted on a total of 600 subjects (150 males and 450 females) in the age group of 18–50 years who were attending the General Outpatient Department and residing in one of the eight districts of …
View article: Bone remodeling, not inflammation, as the predominant pathology in modic type 1 lesions of the lumbar spine
Bone remodeling, not inflammation, as the predominant pathology in modic type 1 lesions of the lumbar spine Open
Purpose Lesions of the vertebral endplates (Modic changes) are associated with low back pain (LBP), and different pathological processes, including inflammation, have been proposed as causative. This study aimed to explore the relationship…
View article: Leptomeningeal metastases in a case of squamous cell carcinoma of the uterine cervix : A case report along with review of literature
Leptomeningeal metastases in a case of squamous cell carcinoma of the uterine cervix : A case report along with review of literature Open
Leptomeningeal metastases (LM) is an extremely rare complication in solid malignancies and an indicator of poor prognosis. Our case is of a 54-year-old lady who was diagnosed with squamous cell carcinoma of the uterine cervix (FIGO Stage I…
View article: Information Extraction from Lumbar Spine MRI Radiology Reports Using GPT4: Accuracy and Benchmarking Against Research-Grade Comprehensive Scoring
Information Extraction from Lumbar Spine MRI Radiology Reports Using GPT4: Accuracy and Benchmarking Against Research-Grade Comprehensive Scoring Open
Background/Objectives: This study aimed to create a pipeline for standardized data extraction from lumbar-spine MRI radiology reports using a large language model (LLM) and assess the agreement of the extracted data with research-grade sem…
View article: Improving radiologist detection of meniscal abnormality on undersampled, deep learning reconstructed knee MRI
Improving radiologist detection of meniscal abnormality on undersampled, deep learning reconstructed knee MRI Open
Background Accurate interpretation of meniscal anomalies on knee MRI is critical for diagnosis and treatment planning, with artificial intelligence emerging as a promising tool to support and enhance this process through automated anomaly …
View article: Foundations of a knee joint digital twin from qMRI biomarkers for osteoarthritis and knee replacement
Foundations of a knee joint digital twin from qMRI biomarkers for osteoarthritis and knee replacement Open
View article: Foundations of a Knee Joint Digital Twin from qMRI Biomarkers for Osteoarthritis and Knee Replacement
Foundations of a Knee Joint Digital Twin from qMRI Biomarkers for Osteoarthritis and Knee Replacement Open
This study forms the basis of a digital twin system of the knee joint, using advanced quantitative MRI (qMRI) and machine learning to advance precision health in osteoarthritis (OA) management and knee replacement (KR) prediction. We combi…
View article: Clinical Utility of Foundation Segmentation Models in Musculoskeletal MRI: Biomarker Fidelity and Predictive Outcomes
Clinical Utility of Foundation Segmentation Models in Musculoskeletal MRI: Biomarker Fidelity and Predictive Outcomes Open
Effective segmentation is fundamental for quantitative medical imaging; however, foundation segmentation models remain insufficiently evaluated for accuracy and biomarker fidelity across the diverse anatomical contexts and imaging protocol…
View article: Higher Posterior Tibial Slope and Lower Medial Proximal Tibial Angle of the Knee Are Associated With Delayed Graft Maturation After Anterior Cruciate Ligament Reconstruction Surgery With Hamstring Autograft
Higher Posterior Tibial Slope and Lower Medial Proximal Tibial Angle of the Knee Are Associated With Delayed Graft Maturation After Anterior Cruciate Ligament Reconstruction Surgery With Hamstring Autograft Open
Level IV, retrospective case series.
View article: Unmet Needs in Spondyloarthritis: Imaging in Axial Spondyloarthritis
Unmet Needs in Spondyloarthritis: Imaging in Axial Spondyloarthritis Open
Imaging biomarkers in axial spondyloarthritis (axSpA) are currently the most specific biomarkers for the diagnosis of this condition. Despite advances in imaging, from plain radiographs—which detect only damage—to magnetic resonance imagin…
View article: The relationships between patellofemoral bone remodeling, cartilage composition, and vertical loading rate: PET/MRI in isolated patellofemoral osteoarthritis
The relationships between patellofemoral bone remodeling, cartilage composition, and vertical loading rate: PET/MRI in isolated patellofemoral osteoarthritis Open
Evidence of simultaneous, complementary, cross-sectional associations between T1p-T2 values and peak vertical loading rates with 18NaF-SUV, have been rare in the isolated PFJ-OA cohort. The clinical implica…
View article: Continuous quality improvement in a community-wide TB screening and prevention programme in Papua New Guinea
Continuous quality improvement in a community-wide TB screening and prevention programme in Papua New Guinea Open
SETTINGDaru Island in Papua New Guinea (PNG) has a high prevalence of TB and multidrug-resistant TB (MDR-TB).OBJECTIVETo evaluate the early implementation of a community-wide project to detect and treat TB disease and infection, outline th…
View article: Artificial intelligence in musculoskeletal applications: a primer for radiologists
Artificial intelligence in musculoskeletal applications: a primer for radiologists Open
As an umbrella term, artificial intelligence (AI) covers machine learning and deep learning. This review aimed to elaborate on these terms to act as a primer for radiologists to learn more about the algorithms commonly used in musculoskele…
View article: Admission screening testing of patients and staff N95 respirators are cost-effective in reducing COVID-19 hospital-acquired infections
Admission screening testing of patients and staff N95 respirators are cost-effective in reducing COVID-19 hospital-acquired infections Open
In acute care settings, staff N95 respirators and admission screening testing of patients can reduce hospital-acquired COVID-19 and COVID-19 deaths, and are cost saving because of reduced patient bed-days and staff replacement needs.
View article: Poster 354: Tibiofemoral Bone Shape Features Are Associated with Re-Tear after Anterior Cruciate Ligament Reconstruction
Poster 354: Tibiofemoral Bone Shape Features Are Associated with Re-Tear after Anterior Cruciate Ligament Reconstruction Open
Introduction: Knee bony morphology is linked to anterior cruciate ligament (ACL) injury, ACL graft failure, and osteoarthritis (OA) risk, and employing tools such as statistical shape modeling could identify individuals prone to these join…
View article: Clinical and imaging findings associated with preservation of knee joint health over 8 years in individuals aged 65 and over: data from the OAI
Clinical and imaging findings associated with preservation of knee joint health over 8 years in individuals aged 65 and over: data from the OAI Open
Objective While risk factors for osteoarthritis (OA) are well known, it is not well understood why certain individuals maintain high mobility and joint health throughout their life while others demonstrate OA at older ages. The purpose of …
View article: Deciphering Osteoarthritis Progression and Knee Replacement Biomarkers: A Digital Twin Analysis via qMRI
Deciphering Osteoarthritis Progression and Knee Replacement Biomarkers: A Digital Twin Analysis via qMRI Open
Osteoarthritis (OA), a prevalent and debilitating condition, poses substantial diagnostic and therapeutic challenges. Our study leverages advanced quantitative MRI to construct a sophisticated 100-dimensional space mapping known risk facto…
View article: Machine learning-based automated scan prescription of lumbar spine MRI acquisitions
Machine learning-based automated scan prescription of lumbar spine MRI acquisitions Open
This study demonstrates the ability of oriented object detection-based models to be trained to prescribe oblique lumbar spine MRI acquisitions without the need of manual annotation or feature engineering and the feasibility of using machin…
View article: Is hip capsule morphology associated with hip pain in patients without another structural correlate?
Is hip capsule morphology associated with hip pain in patients without another structural correlate? Open
View article: Synthetic Knee MRI T1p Maps as an Avenue for Clinical Translation of Quantitative Osteoarthritis Biomarkers
Synthetic Knee MRI T1p Maps as an Avenue for Clinical Translation of Quantitative Osteoarthritis Biomarkers Open
A 2D U-Net was trained to generate synthetic T1p maps from T2 maps for knee MRI to explore the feasibility of domain adaptation for enriching existing datasets and enabling rapid, reliable image reconstruction. The network was developed us…
View article: Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma
Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma Open
BACKGROUNDInformation about the size, airway location, and longitudinal behavior of mucus plugs in asthma is needed to understand their role in mechanisms of airflow obstruction and to rationally design muco-active treatments.METHODSCT lun…