Muthukumaravel Subramanian
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View article: Effects of dengue virus type-2 serotype (DENV-2) on the expression profile of matrix metalloproteinases in THP-1, monocyte cells and their roles in endothelial dysfunctions: protective effect of atorvastatin
Effects of dengue virus type-2 serotype (DENV-2) on the expression profile of matrix metalloproteinases in THP-1, monocyte cells and their roles in endothelial dysfunctions: protective effect of atorvastatin Open
Dengue viral fever is one of the most important arboviral infections, particularly in tropical and subtropical regions. In a dengue infection, monocyte-mediated matrix metalloproteases are speculated to be implicated in tissue damage and v…
View article: Microbiome diversity in mosquitoes and sand flies: implications for vector competence
Microbiome diversity in mosquitoes and sand flies: implications for vector competence Open
Mosquitoes and sand flies are the most important vectors of several human diseases. A comprehensive analysis of the diversity and composition of the microbiome in mosquitoes and sandflies is important. It emphasises shared traits and disti…
View article: Age and sex distribution trends of SARS-CoV-2 infections: Insights from three epidemic waves in Puducherry, India
Age and sex distribution trends of SARS-CoV-2 infections: Insights from three epidemic waves in Puducherry, India Open
Introduction: This study analyzed the age and sex distribution of COVID-19 patients during the initial three COVID-19 waves in Puducherry, India, from August 2020 to March 2022, to understand the distribution of infection across different …
View article: Role of Molecular Diagnosis in Imported Cutaneous Leishmaniasis and Its Public Health Significance in India
Role of Molecular Diagnosis in Imported Cutaneous Leishmaniasis and Its Public Health Significance in India Open
Cutaneous leishmaniasis (CL) is a significant public health concern that affects many countries. This disease is caused by the protozoan parasite Leishmania spp. and is transmitted through the sandflies from the genus Phlebotomus and Lutzo…
View article: Omics Approaches in Understanding Insecticide Resistance in Mosquito Vectors
Omics Approaches in Understanding Insecticide Resistance in Mosquito Vectors Open
In recent years, the emergence of insecticide resistance has been a major challenge to global public health. Understanding the molecular mechanisms of this phenomenon in mosquito vectors is paramount for the formulation of effective vector…
View article: A simple improved method for extracting DNA from ethanol-preserved hard ticks and its applications
A simple improved method for extracting DNA from ethanol-preserved hard ticks and its applications Open
Hard tick exoskeletons, composed primarily of chitin, pose a significant challenge for researchers attempting to extract genetic material. This study presents a simple modified, alternative method for extracting DNA from ethanol-preserved …
View article: Hard Ticks as Vectors: The Emerging Threat of Tick-Borne Diseases in India
Hard Ticks as Vectors: The Emerging Threat of Tick-Borne Diseases in India Open
Hard ticks (Ixodidae) play a critical role in transmitting various tick-borne diseases (TBDs), posing significant global threats to human and animal health. Climatic factors influence the abundance, diversity, and vectorial capacity of tic…
View article: The Molecular Detection of Bacterial Infections of Public Health Importance in Hard Tick (Ixodidae) Nymphs Collected from the Forest Fringes of Western Ghats in the Goa, Karnataka and Maharashtra States of India
The Molecular Detection of Bacterial Infections of Public Health Importance in Hard Tick (Ixodidae) Nymphs Collected from the Forest Fringes of Western Ghats in the Goa, Karnataka and Maharashtra States of India Open
A survey was conducted to determine the human tick-borne bacterial infections in the nymphs which were collected from Western Ghats’ fringe forest areas. Tick nymphs were collected using the flagging method from the villages where cases Ky…
View article: Classifying stages in the gonotrophic cycle of mosquitoes from images using computer vision techniques
Classifying stages in the gonotrophic cycle of mosquitoes from images using computer vision techniques Open
The ability to distinguish between the abdominal conditions of adult female mosquitoes has important utility for the surveillance and control of mosquito-borne diseases. However, doing so requires entomological training and time-consuming …
View article: Classifying stages in the gonotrophic cycle of mosquitoes from images using computer vision techniques
Classifying stages in the gonotrophic cycle of mosquitoes from images using computer vision techniques Open
The ability to distinguish between the abdominal conditions of adult female mosquitoes has important utility for the surveillance and control of mosquito-borne diseases. However, doing so requires entomological training and time-consuming …
View article: Response to insecticides and underlying mechanisms of resistance in the field populations of Aedes aegypti Linnaeus (Diptera: Culicidae) in Puducherry, India
Response to insecticides and underlying mechanisms of resistance in the field populations of Aedes aegypti Linnaeus (Diptera: Culicidae) in Puducherry, India Open
Background & objectives: Mosquito-borne diseases are major threats to human health worldwide. Successful control of vector mosquitoes requires periodic updates on their response to the insecticides that are in use. Different classes of neu…
View article: Analysis of entomological indices for transmission of Japanese encephalitis in Malkangiri district, Odisha State, east central India during 2015–2019
Analysis of entomological indices for transmission of Japanese encephalitis in Malkangiri district, Odisha State, east central India during 2015–2019 Open
There have been repeated episodes of the outbreak of Japanese encephalitis (JE) in Malkangiri district of Odisha State in the recent past. In the current study, we aimed to assess the entomological parameters of JE vectors in the district.…
View article: Eosinophils restrict diesel exhaust particles induced cell proliferation of lung epithelial A549 cells, vial interleukin-13 mediated mechanisms: implications for tissue remodelling and fibrosis
Eosinophils restrict diesel exhaust particles induced cell proliferation of lung epithelial A549 cells, vial interleukin-13 mediated mechanisms: implications for tissue remodelling and fibrosis Open
Diesel exhaust particulates (DEPs) affect lung physiology and cause serious damage to the lungs. A number of studies have demonstrated that eosinophils play a very important role in the development of lung tissue remodelling and fibrosis. …