Stefan O. Schoenberg
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Reduction of Metal Artefacts in Pediatric Imaging - New Possibilities Through Photon Counting Computed Tomography Open
All MAR techniques improved CT number accuracy and significantly reduced image noise, especially near the prothesis. Using the full spectral information protocol in pediatric imaging is reasonable after dose adjustment to pediatric referen…
Lung cancer screening CT acquisition protocols for three generations of CT systems conforming to German legislation Open
Uniform protocol implementation across CT platforms is challenged by hardware and reconstruction disparities. Patient-size-adapted and system-specific protocols are essential to balance diagnostic performance and radiation safety for futur…
Automated AI detection of thoracic aortic dissection on CT imaging Open
Background Aortic dissection (AD) is a life-threatening condition. We developed an artificial intelligence (AI) algorithm capable of robust, accurate, and automated AD detection and sub-classification. Materials and methods Based on 2010–2…
Radiomics-based prediction of HCC response to atezolizumab/bevacizumab Open
Advanced hepatocellular carcinoma (HCC) treatment has evolved with the introduction of atezolizumab/bevacizumab, showing improved outcomes over sorafenib. However, the response varies among patients, particularly between viral and non-vira…
Radiomics Signature of Aging Myocardium in Cardiac Photon-Counting Computed Tomography Open
Background: Cardiovascular diseases are the leading cause of global mortality, with 80% of coronary heart disease in patients over 65. Understanding aging cardiovascular structures is crucial. Photon-counting computed tomography (PCCT) off…
Opportunistic Diagnostics of Dental Implants in Routine Clinical Photon-Counting CT Acquisitions Open
Two-dimensional imaging is still commonly used in dentistry, but does not provide the three-dimensional information often required for the accurate assessment of dental structures. Photon-counting computed tomography (PCCT), a new three-di…
Selective internal radiation with Y-90 resin microspheres (SIRT) for liver metastases of gastro-intestinal stromal tumors (GIST) resistant to tyrosine kinase inhibitor (TKI) therapy Open
Background Hepatic metastases of GIST might be the dominant site of progression and resistant to available tyrosine kinase inhibitors (TKIs). Selective internal radiation therapy (SIRT) offers treatment by intratumoral radiation up to 200 …
Feasibility of on-site CT-FFR analysis on cardiac photon-counting CT in evaluation of hemodynamically significant stenosis in comparison to invasive catheter angiography Open
Delta CT-FFR analysis using PCCT offers a feasible tool in identifying hemodynamically significant coronary artery stenosis and can help to reduce purely diagnostic ICA.
View article: Radiomics-driven spectral profiling of six kidney stone types with monoenergetic CT reconstructions in photon-counting CT
Radiomics-driven spectral profiling of six kidney stone types with monoenergetic CT reconstructions in photon-counting CT Open
Objectives Urolithiasis, a common and painful urological condition, is influenced by factors such as lifestyle, genetics, and medication. Differentiating between different types of kidney stones is crucial for personalized therapy. The pur…
Interrelation of pericoronary adipose tissue texture and coronary artery disease of the left coronary artery in cardiac photon-counting computed tomography Open
Aim Recent research highlights the role of pericoronary adipose tissue (PCAT) in coronary artery disease (CAD) development. PCAT has been recognized as a metabolically active tissue involved in local inflammation and oxidative stress, pote…
View article: Extracranial arteriovenous malformations: a 10-year experience at a German vascular anomaly center and evaluation of diagnostic imaging for endovascular therapy assessment
Extracranial arteriovenous malformations: a 10-year experience at a German vascular anomaly center and evaluation of diagnostic imaging for endovascular therapy assessment Open
Background Arteriovenous malformations (AVMs) account for <3% of vascular anomalies. This study aims to present the 10-year experience of a German vascular anomaly center (VAC) with AVMs and evaluate diagnostic imaging for treatment-releva…
Mobile stroke units services in Germany: A cost‐effectiveness modeling perspective on catchment zones, operating modes, and staffing Open
Background and Purpose Investigating the cost‐effectiveness of future mobile stroke unit (MSU) services with respect to local idiosyncrasies is essential for enabling large‐scale implementation of MSU services. The aim of this study was to…
Development and validation of a digital biopsy model to predict microvascular invasion in hepatocellular carcinoma Open
Background Microvascular invasion is a major histopathological risk factor of postoperative recurrence in patients with hepatocellular carcinoma. This study aimed to develop and validate a digital biopsy model using imaging features to pre…
Textural heterogeneity of liver lesions in CT imaging - comparison of colorectal and pancreatic metastases Open
Purpose Tumoral heterogeneity poses a challenge for personalized cancer treatments. Especially in metastasized cancer, it remains a major limitation for successful targeted therapy, often leading to drug resistance due to tumoral escape me…
View article: Prospective evaluation of quantitative response parameter in patients with Gastrointestinal Stroma Tumor undergoing tyrosine kinase inhibitor therapy—Impact on clinical outcome
Prospective evaluation of quantitative response parameter in patients with Gastrointestinal Stroma Tumor undergoing tyrosine kinase inhibitor therapy—Impact on clinical outcome Open
The purpose of this study was to determine if dual‐energy CT (DECT) vital iodine tumor burden (ViTB), a direct assessment of tumor vascularity, allows reliable response assessment in patients with GIST compared to established CT criteria s…
Streamlining Acute Abdominal Aortic Dissection Management—An AI-based CT Imaging Workflow Open
Life-threatening acute aortic dissection (AD) demands timely diagnosis for effective intervention. To streamline intrahospital workflows, automated detection of AD in abdominal computed tomography (CT) scans seems useful to assist humans. …
Comparing quantitative image parameters between animal and clinical CT-scanners: a translational phantom study analysis Open
Purpose This study compares phantom-based variability of extracted radiomics features from scans on a photon counting CT (PCCT) and an experimental animal PET/CT-scanner (Albira II) to investigate the potential of radiomics for translation…
Virtual Non-Contrast versus True Native in Photon-Counting CT: Stability of Density of Upper Abdominal Organs and Vessels Open
The clinical use of photon-counting CT (PCCT) allows for the generation of virtual non-contrast (VNC) series from contrast-enhanced images. In routine clinical practice, specific issues such as ruling out acute bleeding require non-contras…
Establishing an MSU service in a medium-sized German urban area—clinical and economic considerations Open
Background and purpose Mobile stroke units (MSU) have been demonstrated to improve prehospital stroke care in metropolitan and rural regions. Due to geographical, social and structural idiosyncrasies of the German city of Mannheim, concept…
Unconditional Latent Diffusion Models Memorize Patient Imaging Data: Implications for Openly Sharing Synthetic Data Open
AI models present a wide range of applications in the field of medicine. However, achieving optimal performance requires access to extensive healthcare data, which is often not readily available. Furthermore, the imperative to preserve pat…
Analysis of Epicardial Adipose Tissue Texture in Relation to Coronary Artery Calcification in PCCT: The EAT Signature! Open
(1) Background: Epicardial adipose tissue influences cardiac biology in physiological and pathological terms. As it is suspected to be linked to coronary artery calcification, identifying improved methods of diagnostics for these patients …
View article: Radiomics-Assisted Computed Tomography-Based Analysis to Evaluate Lung Morphology Characteristics after Congenital Diaphragmatic Hernia
Radiomics-Assisted Computed Tomography-Based Analysis to Evaluate Lung Morphology Characteristics after Congenital Diaphragmatic Hernia Open
Purpose: Children with congenital diaphragmatic hernia suffer from long-term morbidity, including lung function impairment. Our study aims to analyze lung morphology characteristics via radiomic-assisted extraction of lung features in pati…
View article: Ultra-low-dose photon-counting CT of paranasal sinus: an <i>in vivo</i> comparison of radiation dose and image quality to cone-beam CT
Ultra-low-dose photon-counting CT of paranasal sinus: an <i>in vivo</i> comparison of radiation dose and image quality to cone-beam CT Open
Purpose This study investigated the differences in subjective and objective image parameters as well as dose exposure of photon-counting CT (PCCT) compared to cone-beam CT (CBCT) in paranasal sinus imaging for the assessment of rhinosinusi…
Development and Validation of a Model for Postpancreatectomy Hemorrhage Risk Open
Importance Postpancreatectomy hemorrhage (PPH) due to postoperative pancreatic fistula (POPF) is a life-threatening complication after pancreatoduodenectomy. However, there is no prediction tool for early identification of patients at high…
Functional lung imaging of 2-year-old children after congenital diaphragmatic hernia repair using dynamic mode decomposition MRI Open
Objectives To investigate the feasibility of non-contrast-enhanced functional lung imaging in 2-year-old children after congenital diaphragmatic hernia (CDH) repair. Methods Fifteen patients after CDH repair were examined using non-contras…
View article: Pericoronary radiomics texture features associated with hypercholesterolemia on a photon-counting-CT
Pericoronary radiomics texture features associated with hypercholesterolemia on a photon-counting-CT Open
Introduction Pericoronary adipose tissue (PCAT) stands in complex bidirectional interaction with the surrounding arteries and is known to be connected to many cardiovascular diseases involving vascular inflammation. PCAT texture may be inf…