Shama Parveen
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View article: Urea induced characterization & structural dynamics of the Nucleocapsid Protein using biophysical and in silico approaches
Urea induced characterization & structural dynamics of the Nucleocapsid Protein using biophysical and in silico approaches Open
View article: Equal Prevalence of Genotypes ON1 and BA of Human Orthopneumovirus in Riyadh, Saudi Arabia, in 2022
Equal Prevalence of Genotypes ON1 and BA of Human Orthopneumovirus in Riyadh, Saudi Arabia, in 2022 Open
Human orthopneumovirus (HOPV) is a major cause of acute respiratory tract infection (ARI) in children around the world. The present study was conceptualized to detect and characterize human orthopneumovirus in 640 NPAs collected from sympt…
View article: A 25-Year Analysis of Liver Disease–Hypertension Comorbid Mortality Trends in the United States, 1999–2023
A 25-Year Analysis of Liver Disease–Hypertension Comorbid Mortality Trends in the United States, 1999–2023 Open
Background Death certificates frequently list both liver disease and hypertension codes, yet trends in this co-occurrence have been underexplored. This study analyzed 25 years of U.S. data to identify patterns in deaths that list both cond…
View article: Piperlongumine mediated apoptosis in cervical cancer cells beyond docking predictions
Piperlongumine mediated apoptosis in cervical cancer cells beyond docking predictions Open
Cervical cancer is the 4th most prevalent cancer in women. Despite its global health impact, cervical cancer research has achieved limited success with various therapies (chemo, radio, chemo-radio, surgery, etc.). Recent decades have seen …
View article: Role of microRNAs in chronic hepatitis E viral infection
Role of microRNAs in chronic hepatitis E viral infection Open
Hepatitis E virus (HEV) is an emerging zoonotic pathogen and it is associated with chronic hepatitis E virus infection (CHE) in immuno-suppressed patients due to failure of viral clearance. A network of the CHE-associated-differentially ex…
View article: Identification of key candidates associated with chronic hepatitis E virus infection
Identification of key candidates associated with chronic hepatitis E virus infection Open
An in-depth understanding into recent development and management of chronic hepatitis E virus (HEV) infection (CHE) is of interest as the underlying molecular mechanisms remain unexplored. The novel analysis conducted on the mRNA expressio…
View article: 3D nanocomposites of β-TCP-H3BO3-Cu with improved mechanical and biological performances for bone regeneration applications
3D nanocomposites of β-TCP-H3BO3-Cu with improved mechanical and biological performances for bone regeneration applications Open
Recently, 3-D porous architecture of the composites play a key role in cell proliferation, bone regeneration, and anticancer activities. The osteoinductive and osteoconductive properties of β-TCP allow for the complete repair of numerous b…
View article: Theoretical simulation on thermal conductivity of TiO2 NPs and CNTs nanocomposite for thermal management
Theoretical simulation on thermal conductivity of TiO2 NPs and CNTs nanocomposite for thermal management Open
View article: Synthesis, Crystal Structure, Hirshfeld Surface Analysis, Anti-Cervical Cancer Activity, Molecular Docking, and Admet Properties of N 1, N3-Di(Pyridin-2-Yl)Malonamide
Synthesis, Crystal Structure, Hirshfeld Surface Analysis, Anti-Cervical Cancer Activity, Molecular Docking, and Admet Properties of N 1, N3-Di(Pyridin-2-Yl)Malonamide Open
View article: Effect of Guggul ash on physico-chemical properties of water
Effect of Guggul ash on physico-chemical properties of water Open
The present paper focuses on properties of Commiphora wightii, Guggul- oleo-gum resin ash and it potential in water purification. The aqueous solution of ash is strongly alkaline (pH-12.57). The minerals-phosphorus, potassium, calcium, mag…
View article: Detection and Treatment of Emerging Contaminants in Wastewater
Detection and Treatment of Emerging Contaminants in Wastewater Open
Detection and Treatment of Emerging Contaminants in Wastewater addresses the critical and pressing need for effective strategies to detect and treat emerging contaminants, thereby mitigating risks associated with their presence in wastewat…
View article: Function of nanomaterials in the treatment of emerging pollutants in wastewater
Function of nanomaterials in the treatment of emerging pollutants in wastewater Open
Freshwater accessibility has grown to be a serious global challenge. The naturally occurring freshwater reserves are contaminated by the increased demographic, industrialization, and climatic changes. The health, environment, economy, and …
View article: Genetic Variability, Heritability, Genetic Advance for Yield and Yield Related Attributes in Chickpea (Cicer arietinum L.)
Genetic Variability, Heritability, Genetic Advance for Yield and Yield Related Attributes in Chickpea (Cicer arietinum L.) Open
The present investigation was carried out with 30 chickpea genotypes to study the genetic variability for yield and yield related traits in chickpea and observed the high significance for all the thirteen characters i.e., germination perce…
View article: Correction: Yadav et al. PLGA-Quercetin Nano-Formulation Inhibits Cancer Progression via Mitochondrial Dependent Caspase-3,7 and Independent FoxO1 Activation with Concomitant PI3K/AKT Suppression. Pharmaceutics 2022, 14, 1326
Correction: Yadav et al. PLGA-Quercetin Nano-Formulation Inhibits Cancer Progression via Mitochondrial Dependent Caspase-3,7 and Independent FoxO1 Activation with Concomitant PI3K/AKT Suppression. Pharmaceutics 2022, 14, 1326 Open
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View article: Structure based docking and biological evaluation towards exploring potential anti-cancerous and apoptotic activity of 6-Gingerol against human prostate carcinoma cells
Structure based docking and biological evaluation towards exploring potential anti-cancerous and apoptotic activity of 6-Gingerol against human prostate carcinoma cells Open
View article: Synthesis, Crystallographic, Spectroscopic, Quantum Chemical Studies and Anticancer Activity of Novel 1-(3-(3, 4-Dimethoxyphenyl)-7-Methoxy-3, 3a, 4, 5-Tetrahydro-2h-Benzo[G]Indazol-2-Yl)Ethan-1-One
Synthesis, Crystallographic, Spectroscopic, Quantum Chemical Studies and Anticancer Activity of Novel 1-(3-(3, 4-Dimethoxyphenyl)-7-Methoxy-3, 3a, 4, 5-Tetrahydro-2h-Benzo[G]Indazol-2-Yl)Ethan-1-One Open
View article: Human RSVA-ON1, The Only Genotype Present During 2019–2020 Winter Season in Riyadh, Saudi Arabia: A Retrospective Study
Human RSVA-ON1, The Only Genotype Present During 2019–2020 Winter Season in Riyadh, Saudi Arabia: A Retrospective Study Open
Aim: The study aimed to analyze human respiratory syncytial virus (hRSV) strains in nasopharyngeal aspirates obtained retrospectively. Materials & methods: Clinical information of ARI patients (n = 53) was accessed and 2nd hypervariable re…
View article: Phytonanomedicine: A therapeutic approach for cervical cancer
Phytonanomedicine: A therapeutic approach for cervical cancer Open
Cervical cancer has historically been the deadliest malignancy in women. It continues to create several health issues, particularly in developing countries. Current management techniques include cisplatin-based chemoradiotherapy and surgic…
View article: Correlation between different retinal layers with visual acuity in diabetic retinopathy patients with clinically significant macular edema
Correlation between different retinal layers with visual acuity in diabetic retinopathy patients with clinically significant macular edema Open
Purpose: To study the corelation between outer retinal layer thickness (ORL), outer photoreceptor segment thickness (PROS), and central macular thickness (CMT) with best-corrected visual acuity (BCVA) in patients having clinically signific…
View article: Identification of Stage-Specific Differentially Expressed Genes and Network Meta-Analysis Reveals Potential Molecular Signatures in Chronic Hepatitis E Virus Infection
Identification of Stage-Specific Differentially Expressed Genes and Network Meta-Analysis Reveals Potential Molecular Signatures in Chronic Hepatitis E Virus Infection Open
Background Hepatitis E virus (HEV) is the major pathogen responsible for chronic hepatitis infection (CHE) in solid organ transplant recipients. As CHE seems to be dependent on patient’s immunological status, in this context, a comprehensi…
View article: Salivary transforming growth factor beta in oral submucous fibrosis: A diagnostic and predictive marker
Salivary transforming growth factor beta in oral submucous fibrosis: A diagnostic and predictive marker Open
Context: Growth factors and cytokines like transforming growth factor beta (TGF-β) play a key role in the pathogenesis of oral submucous fibrosis. Aims: To elucidate the role of Salivary TGF-β isoforms as a predictive and diagnostic marker…
View article: Intrinsic disorder in the open reading frame 2 of hepatitis E virus: a protein with multiple functions beyond viral capsid
Intrinsic disorder in the open reading frame 2 of hepatitis E virus: a protein with multiple functions beyond viral capsid Open
The results predicted ORF2 as a protein with multiple functions besides its role as a capsid protein. Moreover, the occurrence of IDPR/IDP in ORF2 protein suggests that its disordered region might serve as novel drug targets via functionin…
View article: Comparative Transmission Dynamics and Optimal Controls for Chikungunya, Dengue and Zika Virus Infections
Comparative Transmission Dynamics and Optimal Controls for Chikungunya, Dengue and Zika Virus Infections Open
In this study, we used a simple epidemic model and 2015–16 outbreak data of Chikungunya, Dengue and Zika viruses, arthropod mediated infections that are transmitted by the common mosquito vector Aedes aegypti, from Mexico to quantify the t…
View article: Integrative Multiomics and Regulatory Network Analyses Uncovers the Role of OAS3, TRAFD1, miR-222-3p, and miR-125b-5p in Hepatitis E Virus Infection
Integrative Multiomics and Regulatory Network Analyses Uncovers the Role of OAS3, TRAFD1, miR-222-3p, and miR-125b-5p in Hepatitis E Virus Infection Open
The hepatitis E virus (HEV) is a long-ignored virus that has spread globally with time. It ranked 6th among the top risk-ranking viruses with high zoonotic spillover potential; thus, considering its viral threats is a pressing priority. Th…
View article: REVIEW: APPLICATION OF NANOSENSOR IN AGRICULTURE
REVIEW: APPLICATION OF NANOSENSOR IN AGRICULTURE Open
Nano-biosensors play an important role in revolutionizing farming through the development of diagnostic tools and techniques.These sensors are accurate, efficient, and cost-effective in dealing with various food, agriculture, and environme…
View article: Evaluation of Genetic Variability, Heritability and Genetic Advance in Garden Pea (Pisum sativum L.)
Evaluation of Genetic Variability, Heritability and Genetic Advance in Garden Pea (Pisum sativum L.) Open
Ten pea genotypes had their heritability evaluated in 2021 and '22. Except for the proliferation of plants, change analysis has a substantial impact on all other factors. Unit yield per plant (15.3,16.97) had the highest genotypic and phen…
View article: Mathematical modeling in perspective of vector-borne viral infections: a review
Mathematical modeling in perspective of vector-borne viral infections: a review Open
View article: Assessment of Genetic Variability Parameters and Character Association in Chickpea (Cicer arietinum L.)
Assessment of Genetic Variability Parameters and Character Association in Chickpea (Cicer arietinum L.) Open
School of Agriculture, ITM University in Gwalior's Department of Genetics and Plant Breeding performed a Rabi season 2021–2022 study on 15 distinct genotypes of chickpeas to better understand their genetic variability. The genotypes were d…
View article: Development of Highly Sensitive Sandwich ELISA for the Early-Phase Diagnosis of Chikungunya Virus Utilizing rE2-E1 Protein
Development of Highly Sensitive Sandwich ELISA for the Early-Phase Diagnosis of Chikungunya Virus Utilizing rE2-E1 Protein Open
Our simple and sensitive sandwich ELISA for the early-phase detection of CHIKV infection may be used to improve the diagnosis of chikungunya.
View article: Identification of the Key miRNAs and Genes Associated with the Regulation of Non-Small Cell Lung Cancer: A Network-Based Approach
Identification of the Key miRNAs and Genes Associated with the Regulation of Non-Small Cell Lung Cancer: A Network-Based Approach Open
Lung cancer is the major cause of cancer-associated deaths across the world in both men and women. Lung cancer consists of two major clinicopathological categories, i.e., small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC)…