Subashan Perera
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View article: Testing A Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans
Testing A Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans Open
Objective We aimed to test the efficacy of personalized treatment of older Veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABC) as compared with usual care (UC). Methods Two hundred ninety‐nine Veterans age 65‐8…
View article: Gait dual-task cost in individuals with chronic low back pain and high avoidance or catastrophizing
Gait dual-task cost in individuals with chronic low back pain and high avoidance or catastrophizing Open
Individuals with high pain catastrophizing or high pain severity may alter step length and gait symmetry differently than their peers in response to increased cognitive loading. Pain severity, but not pain-related psychological factors, ap…
View article: Characteristics of Evidenced-Based Falls Prevention Program Completers and Non-Completers and Difference in Outcomes
Characteristics of Evidenced-Based Falls Prevention Program Completers and Non-Completers and Difference in Outcomes Open
Evidenced-based community falls prevention programs can reduce falls in older adults. We sought to (1) describe the characteristics of program participants who met completion criteria by receiving the full program dose (completers) versus …
View article: Preoperative factors and four-year decompressive laminectomy success in symptomatic lumbar spinal stenosis
Preoperative factors and four-year decompressive laminectomy success in symptomatic lumbar spinal stenosis Open
Background/context Decompressive laminectomy (DL) for lumbar spinal stenosis (LSS) is the most common spinal surgery for older adults. Biopsychosocial factors are associated with 1-year outcomes in these patients. While most surgical failu…
View article: INTERVENTIONS TO IMPROVE GAIT SPEED
INTERVENTIONS TO IMPROVE GAIT SPEED Open
Numerous evidence-based interventions exist to treat patients’ mobility limitations once identified in primary care. We will present an overview, focusing on the Program to Improve Mobility in Aging (PRIMA) study as one example. Interventi…
View article: Characteristics associated with gait speed improvements from walking interventions for older adults: A responder analysis
Characteristics associated with gait speed improvements from walking interventions for older adults: A responder analysis Open
Those with the combination of suboptimal physical performance and strong self-report of function may benefit from standard strength and conditioning. Individuals may best respond to task-specific training when health status and physical pe…
View article: Adoption, Implementation, and Maintenance of Evidence-Based Falls Prevention Programs
Adoption, Implementation, and Maintenance of Evidence-Based Falls Prevention Programs Open
We evaluate the implementation of evidence-based falls prevention programs (EBFPPs) of the Administration for Community Living (ACL) Grantees by (1) describing adoption; (2) evaluating implementation through participant adherence; and (3) …
View article: Effects of Sedentary Behavior Reduction on Blood Pressure in Desk Workers: Results From the RESET-BP Randomized Clinical Trial
Effects of Sedentary Behavior Reduction on Blood Pressure in Desk Workers: Results From the RESET-BP Randomized Clinical Trial Open
BACKGROUND: Sedentary behavior (SB) is observationally associated with cardiovascular disease risk. However, randomized clinical trials testing causation are limited. We hypothesized that reducing SB would decrease blood pressure (BP) and …
View article: On the Move in the community: Protocol for a hybrid 1 trial examining effectiveness and fidelity of a community-based group exercise program for older adults
On the Move in the community: Protocol for a hybrid 1 trial examining effectiveness and fidelity of a community-based group exercise program for older adults Open
The findings of this trial will 1) establish the effectiveness of OTM on improvements in walking and post-intervention persistence of benefits, 2) assess intervention fidelity and identify the impact of organizational, instructor, and part…
View article: Serial gait speed measurements over time and dynamic survival prediction in older adults
Serial gait speed measurements over time and dynamic survival prediction in older adults Open
The two most recent gait speeds appear sufficient to consider for mortality risk in the present initial analysis. More frequent gait speeds need to be considered in mortality risk prediction before definitive conclusions supporting real-wo…
View article: Activity and Participation Are Associated with Future Falls, Hospitalizations, and Emergency Visits in Community-Dwelling Older Adults
Activity and Participation Are Associated with Future Falls, Hospitalizations, and Emergency Visits in Community-Dwelling Older Adults Open
Objective Activity and participation are important for older adults as they are associated with well-being and quality of life. Falls, emergency department (ED) visits, and hospitalizations are adverse health outcomes that impact older adu…
View article: A molecular index for biological age identified from the metabolome and senescence‐associated secretome in humans
A molecular index for biological age identified from the metabolome and senescence‐associated secretome in humans Open
Unlike chronological age, biological age is a strong indicator of health of an individual. However, the molecular fingerprint associated with biological age is ill‐defined. To define a high‐resolution signature of biological age, we analyz…
View article: Prefrontal cortex activation while walking did not change but gait speed improved after a randomized physical therapy intervention
Prefrontal cortex activation while walking did not change but gait speed improved after a randomized physical therapy intervention Open
Background Higher prefrontal cortex (PFC) activation while walking may indicate reduced gait automaticity. Aim We examine whether PFC activation during walking improves after training in older adults at risk for mobility disability. Method…
View article: Dissemination and implementation of evidence-based programs for people with chronic disease: the impact of the COVID-19 pandemic
Dissemination and implementation of evidence-based programs for people with chronic disease: the impact of the COVID-19 pandemic Open
Background Using the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework, we describe the implementation of evidence-based chronic disease self-management education (CDSME) programs by the Administration for …
View article: Subsidized Versus Unsubsidized Senior Housing Communities in PA: A Window on Variation in Health, Function, and Access to Services in Old Age
Subsidized Versus Unsubsidized Senior Housing Communities in PA: A Window on Variation in Health, Function, and Access to Services in Old Age Open
Introduction: Independent Living residences for older adults can be divided into two categories and require better definitions for research purposes; the purpose of this manuscript is to provide those definitions and explore variation in p…
View article: Global Positioning System Indicators of Community Mobility and Future Health Outcomes Among Older Adults
Global Positioning System Indicators of Community Mobility and Future Health Outcomes Among Older Adults Open
Background We examined the relationship between global positioning system (GPS) indicators of community mobility and incident hospitalizations, emergency department (ED) visits, and falls over 1-year in community-dwelling older adults. Met…
View article: The Association of Bone Turnover Markers with Muscle Function, Falls, and Frailty in Older Women in Long-Term Care
The Association of Bone Turnover Markers with Muscle Function, Falls, and Frailty in Older Women in Long-Term Care Open
In older women residing in LTC facilities, CTX was associated with gait speed, falls history, and frail phenotype, whereas P1NP was only associated with frail phenotype. These findings suggest a relationship between bone remodeling and mus…
View article: Influence of Recent Standing, Moving, or Sitting on Daytime Ambulatory Blood Pressure
Influence of Recent Standing, Moving, or Sitting on Daytime Ambulatory Blood Pressure Open
Background There are no recommendations for being seated versus nonseated during ambulatory blood pressure (BP) monitoring (ABPM). The authors examined how recent standing or moving versus sitting affect average daytime BP on ABPM. Methods…
View article: Impact of sleep on chronobiology of micturition among healthy older adults
Impact of sleep on chronobiology of micturition among healthy older adults Open
Nocturia (waking to void) is the most common cause of sleep interruption among older adults, and increased nighttime urine production is its primary etiology. We showed that in healthy older adults sleep affects the 24-h secretory rhythm o…
View article: Effects of a Physical Therapist Intervention on GPS Indicators of Community Mobility in Older Adults: A Secondary Analysis of a Randomized Controlled Trial
Effects of a Physical Therapist Intervention on GPS Indicators of Community Mobility in Older Adults: A Secondary Analysis of a Randomized Controlled Trial Open
Objective The authors compared the effects of a standard strength and endurance intervention with a standard plus timing and coordination training intervention on community mobility measured using global positioning systems (GPS) among com…
View article: 0146 Associations Between Mood and Sleep Architecture in Sedentary Office Workers
0146 Associations Between Mood and Sleep Architecture in Sedentary Office Workers Open
Introduction Sleep, and rapid eye movement (REM) sleep in particular, has been suggested to play an important role in mood regulation. Currently, most of this research has come from laboratory settings under constrained conditions; less is…