Joel S. Schuman
YOU?
Author Swipe
View article: APOSTEL-R Recommendations for Reporting Retinal Optical Coherence Tomography Studies in Rodents
APOSTEL-R Recommendations for Reporting Retinal Optical Coherence Tomography Studies in Rodents Open
The Advised Protocol for OCT Study Terminology and Elements for reporting OCT studies in rodents (APOSTEL-R) originates from an expert consensus. They will provide guidance throughout the experimental process and will contribute to the sta…
View article: Vis-OCT Explorer: an open-source software for visible-light optical coherence tomography data processing
Vis-OCT Explorer: an open-source software for visible-light optical coherence tomography data processing Open
Background and objectives Visible-light optical coherence tomography (vis-OCT) has enabled the visualization of retinal structures and functions beyond the capabilities of conventional OCTs. However, to reconstruct high-quality images, vis…
Optic Nerve Imaging—From Disc Photos to OCT Open
The diagnosis and monitoring of glaucoma require precise evaluation of ocular structural features. The advent of ocular imaging has revolutionized both the clinical management and research of glaucoma, establishing itself as a cornerstone …
View article: Surgical techniques and outcome assessment of a novel vascularized orthotopic rodent whole eye transplantation model
Surgical techniques and outcome assessment of a novel vascularized orthotopic rodent whole eye transplantation model Open
Currently there are no surgical solutions to restore vision in the irreversibly blind. Whole eye transplantation (WET), is an appealing surgical approach for restoration, replacement, and reconstruction of nonfunctioning eyes. Development …
View article: Normative Variability in Retinal Nerve Fiber Layer Thickness: Does It Matter Where the Peaks Are?
Normative Variability in Retinal Nerve Fiber Layer Thickness: Does It Matter Where the Peaks Are? Open
RNFLT-PN reduces normative variability and improves sectoral abnormality categorization, potentially leading to better sensitivity and specificity of RNFLT measure in glaucoma detection.
View article: Artificial Intelligence for Optical Coherence Tomography in Glaucoma
Artificial Intelligence for Optical Coherence Tomography in Glaucoma Open
This review bridges the gap between basic research and clinical care by demonstrating how AI, particularly DL models, can markedly enhance OCT's clinical utility in diagnosis, monitoring, and prediction, moving toward more individualized, …
View article: Stimulus-driven cerebrospinal fluid dynamics is impaired in glaucoma patients
Stimulus-driven cerebrospinal fluid dynamics is impaired in glaucoma patients Open
Cerebrospinal fluid (CSF) dynamics, driven by sensory stimulation-induced neuronal activity, is crucial for maintaining homeostasis and clearing metabolic waste. However, it remains unclear whether such CSF flow is impaired in age-related …
View article: Cerebellar dysfunction in glaucoma patients
Cerebellar dysfunction in glaucoma patients Open
Glaucoma patients often have higher injurious fall rates compared to healthy older adults. However, little is known about the underlying neural mechanisms. Recent evidence shows cerebral changes beyond the visual pathway of glaucoma patien…
View article: Lamina Cribrosa Microstructure in Nonhuman Primates With Naturally Occurring Peripapillary Retinal Nerve Fiber Layer Thinning
Lamina Cribrosa Microstructure in Nonhuman Primates With Naturally Occurring Peripapillary Retinal Nerve Fiber Layer Thinning Open
Our findings indicate structural alterations in the LC of NHP exhibiting natural thinning of the RNFL, a common characteristic of glaucomatous damage.
High Prevalence of Artifacts in Optical Coherence Tomography With Adequate Signal Strength Open
Application of the deep learning-based OCT image quality assessment models may improve the OCT image data quality for both clinical applications and research.
View article: Endophthalmitis Rates and Types of Treatments After Intraocular Procedures
Endophthalmitis Rates and Types of Treatments After Intraocular Procedures Open
Importance Long-term trend analyses of overall endophthalmitis rates and treatment patterns are scarce. It is also unknown if the deviation from the recommendations of the Endophthalmitis Vitrectomy Study toward decreased utilization of vi…
View article: Contributions of Brain Microstructures and Metabolism to Visual Field Loss Patterns in Glaucoma Using Archetypal and Information Gain Analyses
Contributions of Brain Microstructures and Metabolism to Visual Field Loss Patterns in Glaucoma Using Archetypal and Information Gain Analyses Open
Our findings highlight the importance of non-invasive neuroimaging biomarkers and analytical modeling for unveiling glaucomatous neurodegeneration and how they reflect complementary VF loss patterns.
A Hybrid Deep Learning Classification of Perimetric Glaucoma Using Peripapillary Nerve Fiber Layer Reflectance and Other OCT Parameters from Three Anatomy Regions Open
Precis: A hybrid deep-learning model combines NFL reflectance and other OCT parameters to improve glaucoma diagnosis. Objective: To investigate if a deep learning model could be used to combine nerve fiber layer (NFL) reflectance and other…
View article: Focal Loss Analysis of Peripapillary Nerve Fiber Layer Reflectance for Glaucoma Diagnosis
Focal Loss Analysis of Peripapillary Nerve Fiber Layer Reflectance for Glaucoma Diagnosis Open
Purpose: To evaluate nerve fiber layer (NFL) reflectance for glaucoma diagnosis using a large dataset. Methods: Participants were imaged with 4.9mm ONH scans using spectral-domain optical coherence tomography (OCT). The NFL reflectance map…
View article: Deep-Learning-Based Group Pointwise Spatial Mapping of Structure to Function in Glaucoma
Deep-Learning-Based Group Pointwise Spatial Mapping of Structure to Function in Glaucoma Open
Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
Disparities in Visual Field Testing Frequency Among Subjects With Glaucoma Open
Black and Asian subjects with glaucoma receive fewer VFT per visit compared to White subjects even when considering socioeconomic disadvantage and disease severity.
View article: Peripapillary Atrophy Area as an Indicator of Glaucomatous Structural and Functional Progression
Peripapillary Atrophy Area as an Indicator of Glaucomatous Structural and Functional Progression Open
Longitudinal changes in peripapillary atrophy area measured by OCT can be an indicator of structural and functional glaucoma progression.
View article: Early inner plexiform layer thinning and retinal nerve fiber layer thickening in excitotoxic retinal injury using deep learning-assisted optical coherence tomography
Early inner plexiform layer thinning and retinal nerve fiber layer thickening in excitotoxic retinal injury using deep learning-assisted optical coherence tomography Open
Excitotoxicity from the impairment of glutamate uptake constitutes an important mechanism in neurodegenerative diseases such as Alzheimer’s, multiple sclerosis, and Parkinson's disease. Within the eye, excitotoxicity is thought to play a c…
LIMBARE: An Advanced Linear Mixed-Effects Breakpoint Analysis With Robust Estimation Method With Applications to Longitudinal Ophthalmic Studies Open
Our proposed method and companion R package provide a valuable computational tool for advancing longitudinal ophthalmology research and exploring the association relationships among ophthalmic variables.
Motion Contrast, Phase Gradient, and Simultaneous OCT Images Assist in the Interpretation of Dark-Field Images in Eyes with Retinal Pathology Open
The cellular-level visualization of retinal microstructures such as blood vessel wall components, not available with other imaging modalities, is provided with unprecedented details by dark-field imaging configurations; however, the interp…
Reducing Ophthalmic Health Disparities Through Transfer Learning: A Novel Application to Overcome Data Inequality Open
TL offers an equitable and efficient approach to mitigate healthcare disparities analysis by enhancing prediction performance for data-disadvantaged group.
View article: Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma
Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma Open
Although glaucoma is a disease modulated by eye pressure, the mechanisms of pressure sensing in the eye are not well understood. Here, we investigated associations between mechanosensitive ion channel gene variants and primary open-angle g…
Assessment of Remote Training, At-Home Testing, and Test-Retest Variability of a Novel Test for Clustered Virtual Reality Perimetry Open
Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
View article: Can Glaucoma Suspect Data Help to Improve the Performance of Glaucoma Diagnosis?
Can Glaucoma Suspect Data Help to Improve the Performance of Glaucoma Diagnosis? Open
Clinical imbalanced datasets may negatively affect medical applications of deep learning. Utilizing data with uncertain diagnosis, such as glaucoma suspects, through a combination of semi-supervised learning and class-imbalanced learning s…
View article: Segmentation-Free OCT-Volume-Based Deep Learning Model Improves Pointwise Visual Field Sensitivity Estimation
Segmentation-Free OCT-Volume-Based Deep Learning Model Improves Pointwise Visual Field Sensitivity Estimation Open
DL-based VF surrogates not only benefit patients by reducing the testing time of VFs but also allow clinicians to make clinical judgments without the inherent limitations of VFs.