Khadija Sellami
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View article: Investigating the Expression of LL-37 Antimicrobial Peptide in Autoimmune Bullous Disorders: Implications for Pemphigus
Investigating the Expression of LL-37 Antimicrobial Peptide in Autoimmune Bullous Disorders: Implications for Pemphigus Open
Objective: This study aimed to investigate the expression of the antimicrobial peptide cathelicidin LL-37 and discuss its role as a critical factor in developing pemphigus. Methods: The expression of LL-37 mRNA was assessed in individuals …
View article: P-215 ROLE OF EXPOSURE TO ENVIRONMENTAL AND OCCUPATIONAL FACTORS IN THE OCCURRENCE OF PEMPHIGUS: A CASE-CONTROL STUDY IN TUNISIA
P-215 ROLE OF EXPOSURE TO ENVIRONMENTAL AND OCCUPATIONAL FACTORS IN THE OCCURRENCE OF PEMPHIGUS: A CASE-CONTROL STUDY IN TUNISIA Open
Introduction The pemphigus is a multifactorial dermatosis. While many etiological hypotheses have been suggested for its occurrence, the exact etiology remains to be determined.Our study aimed to identify the role of environmental and occu…
View article: Congenital liquified subcutaneous fat necrosis in a newborn: an unusual case
Congenital liquified subcutaneous fat necrosis in a newborn: an unusual case Open
Subcutaneous fat necrosis of the newborn is a self-limited disorder of the panniculus that arises in the first six weeks of life. Some differential diagnoses may be difficult such as bacterial cellulitis or erysipelas. The prognosis is usu…
View article: Direct medical cost related to the management of pemphigus: A pilot Tunisian study
Direct medical cost related to the management of pemphigus: A pilot Tunisian study Open
Background: Pemphigus is a therapeutically challenging disease with high morbidity and economic burden. First-line prescription of rituximab remains limited in Tunisia due to its high cost. Systemic steroids remain the standard of care but…
View article: Follicular Basaloid Hamartoma and Associated Cutaneous Tumors: Clinical, Histopathological and Dermoscopic Aspects.
Follicular Basaloid Hamartoma and Associated Cutaneous Tumors: Clinical, Histopathological and Dermoscopic Aspects. Open
Several case reports have documented dermoscopic features of a solitary basaloid follicular hamartoma. However, further studies are required to specify any reproducible features.
View article: A longstanding tumor with toe deformity
A longstanding tumor with toe deformity Open
The authors declare no conflicts of interest. Data sharing is not applicable to this article as no new data were created or analyzed in this study.
View article: Unilateral hyperpigmented lesion of the breast
Unilateral hyperpigmented lesion of the breast Open
Muco‐cutaneous melanosis is a benign entity with no progression. Although, dermoscopic features may help to differentiate melanosis from malignant pigmented diseases, histopathology remains crucial for the confirming of melanosis of the ni…
View article: Trichofolliculoma: A Case Series.
Trichofolliculoma: A Case Series. Open
Trichofolliculoma (TF) is a rare benign adnexal follicular tumor, described as hamartoma with follicular differentiation according to some authors. It typically appears during adulthood on the face or scalp as an isolated nodule with protr…
View article: Whitish patches on the buccal mucosa: Role of dermoscopy
Whitish patches on the buccal mucosa: Role of dermoscopy Open
Morsicatio is caused by chronic self‐inflicted biting of the buccal mucosa that results in clinically whitish plaques. It is frequently confused with other dermatological mucosal disorders. To avoid needless invasive procedures, dermoscopy…
View article: Bilateral second branchial cleft fistulae coexisting with bilateral cleft lip and bilateral supra‐auricular fissures
Bilateral second branchial cleft fistulae coexisting with bilateral cleft lip and bilateral supra‐auricular fissures Open
A 4-month-old girl was referred to the dermatology department for bilateral branchial cleft fistula. She was a preterm baby. There was no history of consanguinity. A physical examination found a bilateral cleft lip (Figure 1), and a bilate…
View article: Inverted Follicular Keratosis
Inverted Follicular Keratosis Open
Inverted follicular keratosis (IFK) is a rare benign tumour of the follicular infundibulum characterized by exo-endophytic growing. Generally, the diagnosis of IFK is histopathologically made because clinical differentiation from other les…
View article: Late onset of flesh‐colored papules of the neck
Late onset of flesh‐colored papules of the neck Open
Papular elastorrhexis is a rare, acquired disorder of elastic tissue, occurring in adolescent females, characterized by flesh‐colored monomorphous papules usually located on the trunk and the proximal portion of the extremities. We report …
View article: Lichenoid lesions around the anus: An unusual site of Hailey–Hailey disease
Lichenoid lesions around the anus: An unusual site of Hailey–Hailey disease Open
The anal region is an unusual site of Hailey–Hailey disease. It manifests with lichenoid lesions with crusted erosions around the anus. It should be differentiated from condylomata acuminata, extramammary Paget disease, and bowenoid papulo…
View article: Role of chemical exposure in the incidence of vitiligo: a case–control study in Tunisia
Role of chemical exposure in the incidence of vitiligo: a case–control study in Tunisia Open
Vitiligo is a multifactorial dermatosis with many etiological hypotheses that have been suggested for its occurrence. To our knowledge, few epidemiological studies are available on vitiligo induction factors and particularly on the role of…
View article: Evaluation of X chromosome inactivation in endemic Tunisian pemphigus foliaceus
Evaluation of X chromosome inactivation in endemic Tunisian pemphigus foliaceus Open
Background Almost 5% of the world's population develops an autoimmune disease (AID), it is considered the fourth leading cause of disability for women, who represent 78% of cases. The sex ratio when it comes to the most prevalent AID varie…
View article: Lichen planus pigmentosus post <scp>COVID</scp> ‐19‐vaccination: A case report with literature review
Lichen planus pigmentosus post <span>COVID</span> ‐19‐vaccination: A case report with literature review Open
Lichen planus (LP) is a T cell‐mediated chronic inflammatory disorder. Several clinical variants based on lesion morphology and localization are reported. LPP remains uncommon with an unknown etiology. Besides, some precipitating factors h…
View article: Multiple asymptomatic papules following breast cancer treatment
Multiple asymptomatic papules following breast cancer treatment Open
Acquired lymphangiectasia (AL) represents superficial lymphatic dilatation caused by different processes. It is a consequence of lymphatic damage by an external cause; leading to obstruction of local lymphatic drainage.1 We report a case o…
View article: Oral involvement in lupus erythematosus: A report of three cases
Oral involvement in lupus erythematosus: A report of three cases Open
Sir, Lupus erythematosus (LE) is an autoimmune disease that may rarely affect the oral mucosa. This mucosal damage may be mistaken for lichen planus. Herein, we report three cases of oral lupus. Observation 1: A 41-year-old female, with a …
View article: Acral blisters in neonates: Three rare and benign diseases
Acral blisters in neonates: Three rare and benign diseases Open
Exclusive acral involvement in neonatal pemphigus is unusual. Blisters in neonatal bullous pemphigoid, affecting 2%–3% of newborns of mothers with gestational pemphigoid, can be located in the trunk, limbs and acral areas. Unlike neonatal …
View article: Local Cutaneous Complication after Bacilli Calmette-Guerin Vaccine: Unusual Location
Local Cutaneous Complication after Bacilli Calmette-Guerin Vaccine: Unusual Location Open
Check for updatesHistopathology revealed necrotising granulomas.A chest X-ray and complete screening by a pediatrician did not reveal any abnormalities.Dermatological examination demonstrated the absence of skin scarring in the left upper …
View article: A rare case of melanoma erysipeloides
A rare case of melanoma erysipeloides Open
Malignant melanoma presenting as an inflammatory skin metastasis has been described but is an exceedingly rare phenomenon. We report a case of inflammatory metastasis of cutaneous melanoma (CM).
View article: Unusual facial lesions in H syndrome
Unusual facial lesions in H syndrome Open
H Syndrome is a rare genodermatosis. It may include facial involvement such as: facial telangiectasia, both hypo‐ and hyperpigmented lesions, hirsutism, swollen cheeks due to subcutaneous infiltration and eczematous lesions. We describe a …
View article: An orange peel‐like nodule on the back: A case of Wells syndrome
An orange peel‐like nodule on the back: A case of Wells syndrome Open
Wells syndrome is a rare eosinophilic syndrome, associating inflammatory lesions, suggestive histological images and frequent eosinophilia. Wells syndrome is characterized by multiplicity of anatomoclinical forms. Clinically, lesions may b…
View article: Unusual facial lesions in H syndrome
Unusual facial lesions in H syndrome Open
H Syndrome is a rare genodermatosis. It may include facial involvement such as : facial telangiectasia, both hypo- and hyperpigmented lesions, hirsutism, swollen cheeks due to subcutaneous infiltration and eczematous lesions. We describe a…
View article: A verrucous tumor of the leg: Atypical case of Syringocystadenoma Papilliferum
A verrucous tumor of the leg: Atypical case of Syringocystadenoma Papilliferum Open
Syringocystadenoma Papilliferum (SCAP) is a benign adnexal tumor. Most of the cases present with a solitary lesion in the head and neck region at birth or in early childhood. In fact, only two cases of SCAP on the lower leg have been repor…