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View article: Rapid Chemical Profiling of Filipendula ulmaria Using CPC Fractionation, 2-D Mapping of 13C NMR Data, and High-Resolution LC–MS
Rapid Chemical Profiling of Filipendula ulmaria Using CPC Fractionation, 2-D Mapping of 13C NMR Data, and High-Resolution LC–MS Open
Filipendula ulmaria, commonly known as meadowsweet, is a wild herbaceous flowering plant that is widely distributed in Europe. A range of salicylic acid derivatives and flavonol glycosides have been previously associated with the antirheum…
View article: Prenylated flavonoids from Derris eualata, a first record of Curcumin from Derris
Prenylated flavonoids from Derris eualata, a first record of Curcumin from Derris Open
Derris eualata Bedd. Syn: Aganope thyrsiflora (Benth.) Polhill var. eualata (Bedd.) is a perennial climber that is endemic to India as well as South China and New Guinea. We made a first assessment of the aerial parts of this plant in our …
View article: PHYTOCHEMICAL SCREENING AND PHARMAOCOLOGICAL EVALUATION OF TECOMA GAUDICHAUDI
PHYTOCHEMICAL SCREENING AND PHARMAOCOLOGICAL EVALUATION OF TECOMA GAUDICHAUDI Open
Tecoma gaudichaudi is a tropical flowering plant in the Bignoniaceae family that is used to treat diabetes.The aim of this research was to evaluate antioxidant, anti-inflammatory, and antibacterial properties.Tecoma gaudichaudi ethanolic e…
View article: Separation and Determination of Process Related Impurities in Palbociclib: A Rp-hplc Study
Separation and Determination of Process Related Impurities in Palbociclib: A Rp-hplc Study Open
Aims: A new gradient RP-HPLC method was developed for the separation and determination of process related impurities in Palbociclib.
Methodology: The chromatographic separation was achieved on a Inert sustain swift (C18) column using a mo…
View article: Method Development for the Control of Potential Genotoxic Impurities in Vigabatrin Using Gas Chromatography Techniques and Mass Spectroscopy Detector
Method Development for the Control of Potential Genotoxic Impurities in Vigabatrin Using Gas Chromatography Techniques and Mass Spectroscopy Detector Open
Aim: To develop a sensitive headspace GC-MS method for the determination of potential genotoxic impurities in Vigabatrin.
Place and Duration of Study: The study was performed in SIONC Pharmaceuticals, Visakhapatnam from June 2020 to March…
View article: Silver Hull Buckwheat (Fagopyrum esculentum Moench) is a Part of Nature that Offers Best Health and Honour
Silver Hull Buckwheat (Fagopyrum esculentum Moench) is a Part of Nature that Offers Best Health and Honour Open
The gluten-free pseudocereal Fagopyrum esculentum Moench (Silver hull buckwheat) belongs to the Polygonaceae family, which has a long history of both edible and medicinal use. It's a highly nutritious food ingredient that's been shown to h…
View article: PHYTOCONSTITUENTS FROM THE ROOTS OF CUSCUTA CHINENSIS
PHYTOCONSTITUENTS FROM THE ROOTS OF CUSCUTA CHINENSIS Open
Cuscuta chinensis, a parasitic vine, was used in several traditional medicine systems, and it demonstrated a wider range of pharmacological activities in various diseases. The chemical components from C. chinensis consist mainly of flavono…
View article: TOPICAL DRUG DELIVERY OF GOSSYPIN FROM PRONIOSOMAL GEL FORMULATIONS: IN VITRO EFFICACY AGAINST HUMAN MELANOMA CELLS
TOPICAL DRUG DELIVERY OF GOSSYPIN FROM PRONIOSOMAL GEL FORMULATIONS: IN VITRO EFFICACY AGAINST HUMAN MELANOMA CELLS Open
Objective: This work aimed to establish and formulate the gossypinproniosomal gel drug delivery system.
Methods: Gossypin-loaded proniosomal gels (GPG) was prepared using specific non-ionic surfactants (Spans), followed by particle size (…
View article: Phytochemical and Pharmacological evaluation of hibiscus hispidissimus griff
Phytochemical and Pharmacological evaluation of hibiscus hispidissimus griff Open
To assess phytochemical with pharmacological studies of Hibiscus hispidissimus griff belong to family malavaceae. Preliminary phytochemical analysis reveals the presence of steroids, triterpenes, saponins, steroidal saponins and phenols. E…
View article: Anti-inflammatory and Analgesic Effects of <i>Limnophila repens</i> (Benth.)
Anti-inflammatory and Analgesic Effects of <i>Limnophila repens</i> (Benth.) Open
Based on the study, we can conclude that Limnophila repens had analgesic and anti-inflammatory activity. In addition to organic studies, however, additional phytochemicals are required to evaluate the extra energetic chemicals responsible …
View article: The Pharmacognostic Profile and Biological Potential of Traditional Medicinal Shrub Hibiscus hiritus L.
The Pharmacognostic Profile and Biological Potential of Traditional Medicinal Shrub Hibiscus hiritus L. Open
The proposed study has largely focused on two distinct lines of investigation. In the first approach, efforts have been made to evaluate macroscopic and microscopic pharmacognostic characteristics of Hibiscus hiritus L. In the second appro…
View article: Phytochemical and Pharmacological Screening of Begonia grandis Dryand
Phytochemical and Pharmacological Screening of Begonia grandis Dryand Open
Pharmacognosy Research,2020,12,4,375-379.DOI:10.4103/pr.pr_67_20Published:January 2021Type:Original ArticleAuthors:Srinivasarao Pendy, Krishna Nallamothu, Ganapaty Seru, Sunitha Katta, and Sumanta Mondal Author(s) affiliations:Srinivasarao…
View article: Preparation of Triphala Churna using the Ingredients Obtained from Local Market and Comparative Standardization
Preparation of Triphala Churna using the Ingredients Obtained from Local Market and Comparative Standardization Open
Introduction: In the recent years there has been rapid growth in the field of herbal medicine most of the tradition systems of medicine are accepted universally after standardization only. it very important to develop an essential techniqu…
View article: DERIVATIVE UV SPECTROSCOPIC APPROACHES IN MULTICOMPONENT ANALYSIS–A REVIEW
DERIVATIVE UV SPECTROSCOPIC APPROACHES IN MULTICOMPONENT ANALYSIS–A REVIEW Open
The spectrophotometric multi-component analysis involves spectrum recording and mathematical equations. However, spectral interference poses a major limitation when mixture samples are encountered. To overcome this derivative spectrophotom…
View article: NEW STABILITY-INDICATING ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY METHOD DEVELOPMENT AND VALIDATION OF LENVATINIB MESYLATE IN BULK DRUG AND PHARMACEUTICAL DOSAGE FORMS
NEW STABILITY-INDICATING ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY METHOD DEVELOPMENT AND VALIDATION OF LENVATINIB MESYLATE IN BULK DRUG AND PHARMACEUTICAL DOSAGE FORMS Open
Objective: The objective of the present study was to develop and validate a new stability-indicating method for the quantification of lenvatinib mesylate in bulk drug and pharmaceutical dosage form using ultra performance liquid chromatogr…
View article: ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF IMATINIB MESYLATE AND ITS DIMER IMPURITY IN PHARMACEUTICAL FORMULATION BY REVERSE-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF IMATINIB MESYLATE AND ITS DIMER IMPURITY IN PHARMACEUTICAL FORMULATION BY REVERSE-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY Open
Objective: The present study is to develop a simple, specific, and validated reverse-phase high-performance liquid chromatography (HPLC) method for the determination of imatinib mesylate and its dimer impurity in pharmaceutical dosage form…
View article: Evaluation of Antioxidant, Toxicological and wound healing Properties of Hibiscus rosa-sinensis L. (Malvaceae) ethanolic leaves extract on different Experimental animal models
Evaluation of Antioxidant, Toxicological and wound healing Properties of Hibiscus rosa-sinensis L. (Malvaceae) ethanolic leaves extract on different Experimental animal models Open
Objective: The present research article was conducted to study the toxicity profile, antioxidant potential and wound healing activity of ethanolic leaves extract of Hibiscus rosa-sinensis L. (ELEHR). Materials and Methods: In-vitro antioxi…
View article: Evaluations of healing potential of ethanol extract from Macrothelypteris torresiana (Gaudich) aerial parts
Evaluations of healing potential of ethanol extract from Macrothelypteris torresiana (Gaudich) aerial parts Open
The aim of the present study is to evaluate healing potential of 5% and 10% (w/w) ethanol extract from Macrothelypteris torresiana aerial parts (EEMTAP) in simple ointment (family thelypteridaceae). In excision wound model the ethanol ex…
View article: Phytochemical evaluation of roots of polygonum viscosum buch-ham
Phytochemical evaluation of roots of polygonum viscosum buch-ham Open
Phytochemical evaluation of the chloroform extract of roots of Polygonum viscosum has yielded six compounds, stigmasterol, 7,4-dimethylquercetin, kaempferol, quercetin, myricetin and scutellarein. Among the six compounds isolated and chara…