Explanipedia

Impact of maternal diabetes mellitus on fetal atrial strain Open

Faraz Pathan, Penny Lam, S. Sivapathan, Shahab Pathan, Zhiyu Gao , et al. · 2024

While Maternal Diabetes Mellitus (DM) is well known to affect the size and function of multiple fetal organ systems, effects on developing heart chamber function remain difficult to assess. We sought to determine the independent impact of …

Simultaneous Cardiopulmonary Exercise Testing and Echocardiography for Investigation of Cardiopulmonary Dysfunction in Outpatients: Protocol for a Scoping Review Open

Benjamin Gerhardy, S. Sivapathan, Sam Orde, Lucy Morgan · 2024

Background Cardiopulmonary dysfunction is a complex process with a broad range of etiologies. Investigations performed either at rest or those that only assess the function of a single organ (heart or lungs) are often insufficient. A simul…

A review of current landscape and definition of septic cardiomyopathy Open

S. Sivapathan, B. Gehardy, Faraz Pathan, Sam Orde, Kazuaki Negishi · 2023

Background Septic cardiomyopathy (SCM) is a reversible myocardial dysfunction that is increasingly recognised in critically-ill septic patients. SCM and sepsis cause significant morbidity and mortality. However, the lack of consensus on th…

Sonothrombolysis delivered before percutaneous coronary intervention improves myocardial salvage in ST elevation myocardial infarction Open

Deva Nirthanakumaran, Prajith Jeyaprakash, Faraz Pathan, S. Sivapathan, Christine Madronio , et al. · 2023

Background Sonothrombolysis (STL) is the application of high mechanical index ultrasound whilst infusing an ultrasound contrast agent. Prior studies have shown that STL delivered pre & post primary percutaneous coronary intervention (pPCI)…

Simultaneous Cardiopulmonary Exercise Testing and Echocardiography for Investigation of Cardiopulmonary Dysfunction in Outpatients: Protocol for a Scoping Review (Preprint) Open

Benjamin Gerhardy, S. Sivapathan, Sam Orde, Lucy Morgan · 2023

BACKGROUND Cardiopulmonary dysfunction is a complex process with a broad range of etiologies. Investigations performed either at rest or those that only assess the function of a single organ (heart or lungs) are often insufficient. A simu…

Blunted Coronary Flow Velocity Reserve After Anthracycline Therapy in Breast Cancer Patients Open

Christopher Yu, Prajith Jeyaprakash, Koya Ozawa, S. Sivapathan, Tomoko Negishi , et al. · 2023

A Review of Current Landscape and Definition of Septic Cardiomyopathy Open

S. Sivapathan, B. Gehardy, Faraz Pathan, Kazuaki Negishi, Sam Orde · 2023

Prevalence of Septic Cardiomyopathy in a Tertiary Intensive Care Unit (ICU) Open

S. Sivapathan, Neel Chokshi, Faraz Pathan, Sam Orde · 2023

Right Ventricular Dysfunction and Long-Term Mortality in the Critically Unwell: A Systematic Review and Meta-Analysis Open

Benjamin Gerhardy, S. Sivapathan, Emma Bowcock, Lucy Morgan, Sam Orde · 2023

Pre-Percutaneous Coronary Intervention Sonothrombolysis is Essential to Salvage More Myocardium in STEMI: Data From the REDUCE Pilot Trial Open

Deva Nirthanakumaran, Prajith Jeyaprakash, Faraz Pathan, S. Sivapathan, Christine Madronio , et al. · 2023

A novel echocardiographic risk score for light-chain amyloidosis Open

Paul Geenty, S. Sivapathan, L. Stefani, Matthew Zada, Anita Boyd , et al. · 2023

Aims The prognosis of light-chain (AL) amyloidosis, a plasma cell dyscrasia, is largely determined by the presence of cardiac involvement. Conventional staging is achieved using cardiac biomarkers (high-sensitivity troponin, N-terminal pro…

A novel echocardiographic risk score predicts prognosis in AL-amyloidosis Open

Paul Geenty, S. Sivapathan, L. Stefani, Matthew Zada, Anita Boyd , et al. · 2022

Background Prognosis in light chain (AL) amyloidosis is largely determined by the severity of cardiac involvement. Conventional (Mayo) staging includes 1) hs troponin 2) N-terminal pro-beta natriuretic peptide (NT-pro BNP) and 3)free light…

Alterations in multi-layer strain in AL amyloidosis Open

S. Sivapathan, Paul Geenty, Tejas Deshmukh, Anita Boyd, David Richards , et al. · 2022

Cardiac involvement in AL amyloidosis portends a poor prognosis. 2D-speckle tracking echocardiography (2D-STE) strain can identify subclinical cardiac involvement. This study performed multilayer and multiplanar 2D-STE myocardial strain an…

Cardiotoxic Effect of Modern Anthracycline Dosing on Left Ventricular Ejection Fraction: A Systematic Review and Meta‐Analysis of Placebo Arms From Randomized Controlled Trials Open

Prajith Jeyaprakash, S. Sangha, K. Ellenberger, S. Sivapathan, Faraz Pathan , et al. · 2021

Background Anthracyclines are a key chemotherapeutic agent used against hematological and solid organ malignancies. However, their benefits in cancer survival are limited by cumulative, dose‐related cardiotoxicity. The impact of anthracycl…

644 The Impact of a Nurse Led Heart Failure Optimization Clinic Open

В. Paul, Amy Joseph, S. Sivapathan, Christine Madronio, Faraz Pathan · 2020

278 A Real World Comparison of Body Surface Area Formulae Open

K. Ellenberger, K. Neigishi, Winston Thai, Prajith Jeyaprakash, S. Sivapathan , et al. · 2020

499 Impact of Bushfire Season on Cardiology Service Attendance Open

S. Sivapathan, Prajith Jeyaprakash, K. Solomon, Faraz Pathan, Kazuaki Negishi · 2020

013 Maternal Diabetes Impairs Foetal Atrial Function Open

Faraz Pathan, S. Sivapathan, Penny Lam, Ralph Nanan, Kazuaki Negishi · 2020

P309 The use of echocardiographic parameters to predict clinical outcomes in AL-amyloidosis cardiomyopathy Open

Paul Geenty, S. Sivapathan, Tejas Deshmukh, P. Brown, Anita Boyd , et al. · 2020

Background AL-amyloidosis has a rapid clinical progression, with cardiac involvement associated with a particularly poor prognosis. Cardiac amyloidosis is diagnosed by either invasive biopsy or conventional echocardiographic parameters suc…

P1378 Impact of maternal diabetes on fetal left atrial function Open

Faraz Pathan, Penny Lam, S. Sivapathan, Sam Orde, Kazuaki Negishi , et al. · 2020

Background/Introduction: Diabetes impacts 12- 14% of pregnancies. Evaluating the impact of maternal diabetes on the fetal heart is challenging due to variable image quality and limited time for structural changes to manifest. Left atrial r…

P790 Bi-ventricular dysfunction in patients after bone marrow transplant: the value of strain imaging Open

Tejas Deshmukh, Paul Geenty, Lucy E Geraghty, D. Emmerig, S. Sivapathan , et al. · 2020

Background Cardiovascular events are a significant cause of morbidity and mortality in cancer survivors, particularly occurring at 5-10 years after their cancer therapy. Purpose To assess the utility of strain imaging by 2-dimensional (2D)…

887 STEMI in the Time of COVID-19: NSW Data Open

Prajith Jeyaprakash, Lynn Khor, Karan Madan, S. Sivapathan, Lisa Hill , et al. · 2020

The use of 2-Dimensional Strain Imaging for the Detection of Right Ventricular Dysfunction After Bone Marrow Transplantation Involving Anthracycline Chemotherapy Open

Paul Geenty, Tejas Deshmukh, S. Sivapathan, Lucy E Geraghty, D. Emmering , et al. · 2019

Right Ventricular Dysfunction in AL-Amyloidosis Cardiomyopathy Open

Paul Geenty, S. Sivapathan, Tejas Deshmukh, Anita Boyd, P. Brown , et al. · 2019

Alterations in Multiplanar Strain in Bone Marrow Transplant Patients Previously Treated with Anthracyclines Open

Tejas Deshmukh, Lucy E Geraghty, D. Emmerig, S. Sivapathan, Megan Hogg , et al. · 2019

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