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View article: HYPOFRACTIONATED RADIOTHERAPY FOR GLIOBLASTOMA: A RETROSPECTIVE, SINGLE-CENTRE, 12-YEAR EXPERIENCE
HYPOFRACTIONATED RADIOTHERAPY FOR GLIOBLASTOMA: A RETROSPECTIVE, SINGLE-CENTRE, 12-YEAR EXPERIENCE Open
AIMS Hypofractionated radiotherapy is used in older and less fit patients with glioblastoma; however, there have been no head-to-head trials comparing dose/fractionation schedules. Here, we present real-world data from patients treated at o…
View article: Induction chemotherapy followed by chemoradiation in locally advanced cervical cancer: Quality of life outcomes of the GCIG INTERLACE trial
Induction chemotherapy followed by chemoradiation in locally advanced cervical cancer: Quality of life outcomes of the GCIG INTERLACE trial Open
IC added to CRT does not adversely impact QoL compared to CRT, either during IC, during CRT or later.
View article: Hydroxychloroquine in combination with platinum doublet chemotherapy as first-line treatment for extensive-stage small cell lung cancer (Study 15): A randomised phase II multicentre trial
Hydroxychloroquine in combination with platinum doublet chemotherapy as first-line treatment for extensive-stage small cell lung cancer (Study 15): A randomised phase II multicentre trial Open
72 patients were randomised (36 HCQ+chemotherapy and 36 chemotherapy alone). Median HCQ treatment duration was 4.4 months. HCQ did not improve PFS (HR 1·12 95 %CI 0·69-1.84; p = 0·64), with a median of 5.7 months (HCQ+chemotherapy) versus …