Vikas Kumar
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View article: Metabolic-dysfunction associated steatotic liver disease and atrial fibrillation: A review of pathogenesis
Metabolic-dysfunction associated steatotic liver disease and atrial fibrillation: A review of pathogenesis Open
Metabolic dysfunction-associated steatotic liver disease (MASLD) significantly contributes to cardiovascular morbidity, with cardiovascular disease being the leading cause of mortality among affected individuals. Atrial fibrillation (AF), …
View article: Pseudomembranous Colitis: Unveiling an Infrequent Culprit Beyond <i>Clostridium difficile</i> —A Case Report
Pseudomembranous Colitis: Unveiling an Infrequent Culprit Beyond <i>Clostridium difficile</i> —A Case Report Open
Immunotherapy-induced pseudomembranous colitis (PMC) is an uncommon but increasingly recognized adverse effect of immune checkpoint inhibitors, particularly in patients with advanced malignancies. We present a case of a 68-year-old male wi…
View article: Dynamical Modeling of Forest Depletion under Population and Socio-Economic Pressures for Environmental Sustainability
Dynamical Modeling of Forest Depletion under Population and Socio-Economic Pressures for Environmental Sustainability Open
Forest resources, which are essential for biodiversity conservation, climate regulation and ecosystem stability facing severe threats from human activities like population increase, industrialization and socioeconomic pressures. This resea…
View article: The role of generative AI tools in shaping mechanical engineering education from an undergraduate perspective
The role of generative AI tools in shaping mechanical engineering education from an undergraduate perspective Open
This study evaluates the effectiveness of three leading generative AI tools-ChatGPT, Gemini, and Copilot-in undergraduate mechanical engineering education using a mixed-methods approach. The performance of these tools was assessed on 800 q…
View article: Smart driving assistance system for mining operations in foggy environments
Smart driving assistance system for mining operations in foggy environments Open
Environmental conditions such as fog and rain are among the most challenging scenarios for drivers of heavy vehicles in open-pit mines. This paper proposes an efficient camera-based driving assistance system to improve image quality for op…
View article: Beyond Routine Monitoring: A Comprehensive Review of Direct Oral Anticoagulants and the Role of Coagulation Profiles in Their Management
Beyond Routine Monitoring: A Comprehensive Review of Direct Oral Anticoagulants and the Role of Coagulation Profiles in Their Management Open
Direct oral anticoagulants (DOACs) have revolutionized anticoagulation therapy, providing effective and safe management of thrombosis and related conditions. As their use continues to grow, accurately monitoring their effects is essential …
View article: Efficacy of Plain Versus Hyperbaric 0.75% Ropivacaine for SpinalAnaesthesia in Elective Lower Abdominal and Lower Limb Procedures
Efficacy of Plain Versus Hyperbaric 0.75% Ropivacaine for SpinalAnaesthesia in Elective Lower Abdominal and Lower Limb Procedures Open
Background: Spinal anaesthesia with ropivacaine is widely used for lower abdominal and lower limb surgeriesdue to its favorable sensory-motor separation and safety profile. The baricity of the local anaesthetic solutioninfluences onset tim…
View article: Incidence of left ventricular diastolic dysfunction in patients with subclinical hypothyroidism
Incidence of left ventricular diastolic dysfunction in patients with subclinical hypothyroidism Open
Background: Subclinical hypothyroidism (SCH) is a common endocrine disorder categorized by increased serum thyroid-stimulating hormone (TSH) levels with normal free thyroxine (FT4) levels. The study determined the prevalence of LVDD in fem…
View article: Structural insights, regulation, and recent advances of RAS inhibitors in the MAPK signaling cascade: a medicinal chemistry perspective
Structural insights, regulation, and recent advances of RAS inhibitors in the MAPK signaling cascade: a medicinal chemistry perspective Open
Normal and oncogenic RAS signalling pathway along with inhibitors.
View article: Analysis of Mechanical and Microstructure Properties for FCAW Welded IS 2062 Steel Bead
Analysis of Mechanical and Microstructure Properties for FCAW Welded IS 2062 Steel Bead Open
Production rate and excellent metal deposition rate makes Flux cored arc welding (FCAW) unique among all welding process. The application of FCAW in field of structure joining of high strength allow steel is large. The base metal consists …
View article: Recovering orthogonality from quasi‐type kernel polynomials using specific spectral transformations
Recovering orthogonality from quasi‐type kernel polynomials using specific spectral transformations Open
In this work, the concept of quasi‐type Kernel polynomials with respect to a moment functional is introduced. Difference equation satisfied by these polynomials along with the criterion for orthogonality conditions are discussed. The proce…
View article: Interdigitated Electrodes (IDEs)-Supported Biosensing for Efficient Point-of-Care Applications
Interdigitated Electrodes (IDEs)-Supported Biosensing for Efficient Point-of-Care Applications Open
Developing efficient micro-/nano-enabled sensing platforms based on the 5th and 6th generation is an escalating field where the data can be collected, transferred, and analyzed using AI and IoT systems in point-of-care (POC) situations. Fo…
View article: Enhancing Herbal Efficacy: Synthesis and Evaluation of Nanosuspension from Withania somnifera Root Extract
Enhancing Herbal Efficacy: Synthesis and Evaluation of Nanosuspension from Withania somnifera Root Extract Open
Background: Ayurveda emphasizes the balance of mind, body, and spirit, drawing on ancient texts that highlight the medicinal properties of herbs like Withania somnifera, known for its wide range of therapeutic applications and pharmacologi…
View article: Metformin’s dual impact on Gut microbiota and cardiovascular health: A comprehensive analysis
Metformin’s dual impact on Gut microbiota and cardiovascular health: A comprehensive analysis Open
Cardiovascular diseases (CVD) cause significant global morbidity, mortality and public health burden annually. CVD alters richness, diversity, and composition of Gut microbiota along with RAS and histopathological differences. Present stud…
View article: Trends of autoimmune liver disease inpatient hospitalization and mortality from 2011 to 2017: A United States nationwide analysis
Trends of autoimmune liver disease inpatient hospitalization and mortality from 2011 to 2017: A United States nationwide analysis Open
BACKGROUND Autoimmune liver diseases (AiLD) encompass a variety of disorders that target either the liver cells (autoimmune hepatitis, AIH) or the bile ducts [(primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC)]. T…
View article: Orthogonality of quasi-nature spectral polynomials of Jacobi and Laguerre type
Orthogonality of quasi-nature spectral polynomials of Jacobi and Laguerre type Open
In this work, the explicit expressions of coefficients involved in quasi Christoffel polynomials of order one and quasi-Geronimus polynomials of order one are determined for Jacobi polynomials. These coefficients are responsible for establ…
View article: Landslide monitoring and prediction system using geosensors and wireless sensor network
Landslide monitoring and prediction system using geosensors and wireless sensor network Open
Landslides in hilly regions are a frequently occurring natural phenomenon which takes a heavy toll of human lives and causes damage to different properties. Hence, prediction of landslide is essential for averting its deleterious effects b…