Sushma Sagar
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View article: P44 Multi-source environmental reservoirs drive <i>Enterobacter cloacae</i> complex transmission: genomic evidence from an LMIC hospital outbreak investigation
P44 Multi-source environmental reservoirs drive <i>Enterobacter cloacae</i> complex transmission: genomic evidence from an LMIC hospital outbreak investigation Open
Background The Enterobacter cloacae complex (ECC) is increasingly recognized as a major opportunistic pathogen in healthcare-associated infections (HAIs), particularly in intensive care settings. Its clinical relevance has risen in paralle…
View article: Epidemiology of non-central line-associated primary bloodstream infections in a network of Indian hospitals: A prospective surveillance study over 7 years (2017-2024)
Epidemiology of non-central line-associated primary bloodstream infections in a network of Indian hospitals: A prospective surveillance study over 7 years (2017-2024) Open
View article: Prehospital care: Lessons learned from 311 mortalities at level I trauma center
Prehospital care: Lessons learned from 311 mortalities at level I trauma center Open
Augmentation of prehospital care and EMS infrastructure in low-resource settings is crucial to mitigating trauma mortality. Although prehospital care delayed hospital arrival, it positively impacted physiological parameters and potentially…
View article: Burden and Antimicrobial Resistance Trends of Catheter-Associated and Non-Catheter UTIs in Trauma Care: A Retrospective Analysis (2017–2024)
Burden and Antimicrobial Resistance Trends of Catheter-Associated and Non-Catheter UTIs in Trauma Care: A Retrospective Analysis (2017–2024) Open
Background:Catheter-associated urinary tract infections (CAUTIs) are a major healthcare-associated infection (HAI) in trauma care settings, contributing to morbidity, mortality and antimicrobial resistance. In this study we characterize th…
View article: Profile of central line-associated bloodstream infections in adult, paediatric, and neonatal intensive care units of hospitals participating in a health-care-associated infection surveillance network in India: a 7-year multicentric study
Profile of central line-associated bloodstream infections in adult, paediatric, and neonatal intensive care units of hospitals participating in a health-care-associated infection surveillance network in India: a 7-year multicentric study Open
For the Hindi translation of the abstract see Supplementary Materials section.
View article: Assessment of antibiotic utilization patterns in an Indian Level-1 Trauma Center: a pilot study exploring days of antibiotic spectrum coverage and defined daily doses using WHO AWaRe classification trends
Assessment of antibiotic utilization patterns in an Indian Level-1 Trauma Center: a pilot study exploring days of antibiotic spectrum coverage and defined daily doses using WHO AWaRe classification trends Open
Background Rising antimicrobial resistance (AMR) necessitates innovative metrics, such as days of antibiotic spectrum coverage (DASC), to optimize antibiotic stewardship. This study evaluated antibiotic use in an Indian trauma center using…
View article: Clinical determinants for survival following emergency thoracotomy in trauma patients: An 8-year experience from a level 1 trauma center
Clinical determinants for survival following emergency thoracotomy in trauma patients: An 8-year experience from a level 1 trauma center Open
ET can be a life-saving procedure with good outcomes, provided a careful selection of patients based on the mechanism of injury, location of major injury, and signs of life. It is prudent to have a system with proper protocol and a swiftly…
View article: Impact of SARS-CoV-2 Infection on the Outcomes of Trauma Patients at a Level I Trauma Center: An Ambispective Observational Study
Impact of SARS-CoV-2 Infection on the Outcomes of Trauma Patients at a Level I Trauma Center: An Ambispective Observational Study Open
Trauma patients with concomitant SARS-CoV-2 infection had a longer duration of ICD, along with an increased incidence of chest infections and ARDS. A greater proportion of SARS-CoV-2-positive trauma patients required ventilatory support. T…
View article: Transmission dynamics of multidrug resistant Klebsiella pneumoniae from an Indian hospital
Transmission dynamics of multidrug resistant Klebsiella pneumoniae from an Indian hospital Open
This study concludes that environment play essential role in disseminating the infectious strains of organism resulting in increased rates of hospital acquired infections. Therefore, there is an imperative necessity for implementing infect…
View article: Role of 3D Image Processing and Printing in the Diagnosis and Treatment Planning for Maxillofacial Surgery
Role of 3D Image Processing and Printing in the Diagnosis and Treatment Planning for Maxillofacial Surgery Open
Visualization plays an important role in diagnosis and treatment planning for patient care. To provide state-of-the-art care for individuals, especially for secondary reconstruction in cases of trauma, tumor or congenital defects, 3D image…
View article: Ultrasound as a Diagnostic Tool in Detection of Maxillofacial Fractures at Level 1 Trauma Centre <scp>ED</scp> in India
Ultrasound as a Diagnostic Tool in Detection of Maxillofacial Fractures at Level 1 Trauma Centre <span>ED</span> in India Open
Background Injuries, especially maxillofacial fractures, pose a significant global health burden exacerbated by increasing traffic activities. Early detection is vital for preventing complications. This study assesses ultrasound's diagnost…
View article: Effect of rTMS of DLPFC on pain, quality of life, anxiety, and depression in phantom limb pain patients
Effect of rTMS of DLPFC on pain, quality of life, anxiety, and depression in phantom limb pain patients Open
View article: Suppression of meiotic crossovers in pericentromeric heterochromatin requires synaptonemal complex and meiotic recombination factors in <i>Drosophila melanogaster</i>
Suppression of meiotic crossovers in pericentromeric heterochromatin requires synaptonemal complex and meiotic recombination factors in <i>Drosophila melanogaster</i> Open
The centromere effect (CE) is a meiotic phenomenon that ensures meiotic crossover suppression in pericentromeric regions. Despite being a critical safeguard against nondisjunction, the mechanisms behind the CE remain unknown. Previous stud…
View article: Surveillance for surgical site infections developed during hospital stay & after discharge: A multicentric study
Surveillance for surgical site infections developed during hospital stay & after discharge: A multicentric study Open
Background & objectives Surgical site infections (SSIs) are among the most prevalent healthcare-associated infections (HCAIs). They cause significant morbidity, leading to excess health expenditures and increased length of hospital stay. D…
View article: Relevance of intra-abdominal pressure monitoring in non-operative management of patients with blunt liver and splenic injuries
Relevance of intra-abdominal pressure monitoring in non-operative management of patients with blunt liver and splenic injuries Open
As a part of NOM, IAP should be monitored as a continuous vital. However, the decision for any intervention, either operative or non-operative cannot be guided by IAP values alone.
View article: INVISIBLE STRUGGLES: EXPLORING CHALLENGES FACED BY WOMEN WITH AMPUTATION IN INDIA
INVISIBLE STRUGGLES: EXPLORING CHALLENGES FACED BY WOMEN WITH AMPUTATION IN INDIA Open
Women in India, particularly those with amputation, face significant challenges, including but not limited to, unequal prosthetic access and satisfaction, societal discrimination, and the physical and emotional consequences of amputation. …
View article: An Experimental Study Conducted on Material Properties Used in a FDM Printer for Medical Models
An Experimental Study Conducted on Material Properties Used in a FDM Printer for Medical Models Open
3D Printing /Additive manufacturing holds a promising future in healthcare as it aids in visualizing things and making 3D objects which is very important in different areas of medicine. The concept of one size fits all has failed the quali…
View article: An Experimental Study and Review to Demonstrate Mechanical and Material Characteristics of 9 Popular Filaments for 3D Printing
An Experimental Study and Review to Demonstrate Mechanical and Material Characteristics of 9 Popular Filaments for 3D Printing Open
The dynamic landscape of 3D printing has experienced a notable surge in the development of diverse filaments tailored for a wide range of applications in medicine. This experimental study thoroughly examines the mechanical properties of ni…
View article: Effect of severity of injury on immune system and its role in patient outcome in patients with Blunt Trauma to the chest
Effect of severity of injury on immune system and its role in patient outcome in patients with Blunt Trauma to the chest Open
BACKGROUND Chest injuries are one of the most common injuries which are admitted in the trauma and emergency departments. It is known that the immune system affects the outcome of patients with significant trauma though the specific role o…
View article: Outcomes of Video-assisted Thoracic Surgery-guided Early Evacuation of Traumatic Hemothorax: A Randomized Pilot Study at Level I Trauma Center
Outcomes of Video-assisted Thoracic Surgery-guided Early Evacuation of Traumatic Hemothorax: A Randomized Pilot Study at Level I Trauma Center Open
Introduction: Traumatic hemothorax is accounted for about 20% of traumatic chest injuries. Although majority can be managed with the timely placement of intercostal tube (ICT) drainage, the remaining pose a challenge owing to high complica…
View article: Chemo-profiling of Purpureocillium lilacinum and Paecilomyces variotii isolates using GC-MS analysis, and evaluation of their metabolites against M. incognita
Chemo-profiling of Purpureocillium lilacinum and Paecilomyces variotii isolates using GC-MS analysis, and evaluation of their metabolites against M. incognita Open
Nematophagous fungi are the best alternatives to chemical nematicides for managing nematodes considering environmental health. In the current study, activity of metabolites from ten isolates of Purpureocillium lilacinum (Thom) Luangsa-ard …
View article: Role of Low-pressure Negative Pleural Suction in Patients With Thoracic Trauma - a Randomized Controlled Trial.
Role of Low-pressure Negative Pleural Suction in Patients With Thoracic Trauma - a Randomized Controlled Trial. Open
Background: Thoracic trauma frequently includes a pneumothorax, hemothorax, or hemopneumothorax, which may necessitate an Intercostal drainage (ICD) for air and fluid evacuation to improve breathing and circulatory function. It is a simple…
View article: An Experimental Study Conducted on Material Properties Used in A FDM Printer for Medical Models
An Experimental Study Conducted on Material Properties Used in A FDM Printer for Medical Models Open
View article: Epidemiology and Analysis of Mortality in Trauma Patients at a Level I Trauma Center from a Developing Nation
Epidemiology and Analysis of Mortality in Trauma Patients at a Level I Trauma Center from a Developing Nation Open
View article: Impact of Yoga Intervention on Functional Assessment and Quality of Life in Pelvic Injury Patients at Level-1 Trauma Center – A Randomized Control Trial
Impact of Yoga Intervention on Functional Assessment and Quality of Life in Pelvic Injury Patients at Level-1 Trauma Center – A Randomized Control Trial Open
A BSTRACT Introduction: Pelvic fractures are severe injuries that are frequently accompanied by multiple system injuries and also lead to various complications. Thus, pelvic injuries bring a dramatic change in the life situation of an indi…
View article: Impact of early and empirical cryoprecipitate administration on the transfusion requirements in trauma patients with hemorrhagic shock
Impact of early and empirical cryoprecipitate administration on the transfusion requirements in trauma patients with hemorrhagic shock Open
BACKGROUND: Fibrinogen is the earliest coagulation factor falling to the critical levels in severely bleeding trauma patients. Early fibrinogen supplementation in these patients has been recommended to improve the patient outcomes. However…
View article: Analysis and approach to renal trauma: A five-year experience at a level I trauma centre in north India
Analysis and approach to renal trauma: A five-year experience at a level I trauma centre in north India Open
View article: Revisiting the Role of Amniotic Membrane Dressing in Acute Large Traumatic Wounds: A Randomized Feasibility Study at a Level 1 Trauma Centre
Revisiting the Role of Amniotic Membrane Dressing in Acute Large Traumatic Wounds: A Randomized Feasibility Study at a Level 1 Trauma Centre Open
Introduction: Acute large traumatic wounds require temporary dressing prior to the definitive soft tissue reconstruction, as the physiological derangement during the immediate postinjury period delays the definitive surgical intervention. …
View article: Assessment of Psychological Well-being Among Medical Professionals Working with Patients Who Suffer from Physical Trauma: An Observational Study from India
Assessment of Psychological Well-being Among Medical Professionals Working with Patients Who Suffer from Physical Trauma: An Observational Study from India Open
Gupta S, Bhatia G, Sagar R, Sagar S. Assessment of Psychological Well-being Among Medical Professionals Working with Patients Who Suffer from Physical Trauma: An Observational Study from India. Indian J Crit Care Med 2023;27(7):493-502.
View article: Eight year study on evolution of antimicrobial resistance in an antimicrobial-naïve trauma population
Eight year study on evolution of antimicrobial resistance in an antimicrobial-naïve trauma population Open
From 1st January 2012-31st December 2019, 4305 isolates were obtained from 1969 patients. Most frequent occurring organism were gram negatives among which A. baumannii was common followed by K. pneumoniae, and P. aeruginosa. Retrospective …