Soon Won Hong
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View article: TERT mutations and aggressive histopathologic characteristics of radioiodine-refractory papillary thyroid cancer
TERT mutations and aggressive histopathologic characteristics of radioiodine-refractory papillary thyroid cancer Open
Background: Radioiodine (RI) ablation following thyroid-stimulating hormone suppression is an effective treatment for papillary thyroid cancer (PTC), typically leading to favorable outcomes. However, RI-refractory tumors exhibit aggressive…
View article: Gut microbiome predicts cognitive function and depressive symptoms in late life
Gut microbiome predicts cognitive function and depressive symptoms in late life Open
Depression in older adults with cognitive impairment increases progression to dementia. Microbiota is associated with current mood and cognition, but the extent to which it predicts future symptoms is unknown. In this work, we identified m…
View article: Trouble-makers in cytologic interpretation of the uterine cervix
Trouble-makers in cytologic interpretation of the uterine cervix Open
The development and standardization of cytologic screening of the uterine cervix has dramatically decreased the prevalence of squamous cell carcinoma of the uterine cervix. Advances in the understanding of biology of human papillomavirus h…
View article: Supplementary Data from Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer
Supplementary Data from Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer Open
Supplementary Figures S1-S6; Supplementary Tables S1-S2.
View article: Supplementary Data from Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer
Supplementary Data from Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer Open
Supplementary Figures S1-S6; Supplementary Tables S1-S2.
View article: Data from Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer
Data from Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer Open
Purpose: Despite continual efforts to develop a prognostic model of gastric cancer by using clinical and pathologic parameters, a clinical test that can discriminate patients with good outcomes from those with poor outcomes after gastric c…
View article: Data from Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer
Data from Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer Open
Purpose: Despite continual efforts to develop a prognostic model of gastric cancer by using clinical and pathologic parameters, a clinical test that can discriminate patients with good outcomes from those with poor outcomes after gastric c…
View article: Fine Needle Aspiration Cytology vs. Core Needle Biopsy for Thyroid Nodules: A Prospective, Experimental Study Using Surgical Specimen
Fine Needle Aspiration Cytology vs. Core Needle Biopsy for Thyroid Nodules: A Prospective, Experimental Study Using Surgical Specimen Open
In this experimental study using surgical specimens, CNB showed a potential to provide improved diagnostic sensitivity for thyroid cancer, especially when a conclusive diagnosis is limited with FNA.
View article: A retrospective cytohistological correlation of fine-needle aspiration cytology with classification by the Milan System for Reporting Salivary Gland Cytopathology
A retrospective cytohistological correlation of fine-needle aspiration cytology with classification by the Milan System for Reporting Salivary Gland Cytopathology Open
The newly proposed MSRSGC appears to be a reliable system for classification of salivary gland lesions according to the associated ROM.
View article: Current status of cytopathology practices in Korea: annual report on the Continuous Quality Improvement program of the Korean Society for Cytopathology for 2018
Current status of cytopathology practices in Korea: annual report on the Continuous Quality Improvement program of the Korean Society for Cytopathology for 2018 Open
This study represents the current status of cytopathology practices in Korea, illustrating the importance of the Continuous Quality Improvement program for increasing the accuracy and credibility of cytopathologic exams as well as developi…
View article: A Multi-institutional Study of Prevalence and Clinicopathologic Features of Non-invasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP) in Korea
A Multi-institutional Study of Prevalence and Clinicopathologic Features of Non-invasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP) in Korea Open
The low prevalence and indolent clinical outcome of NIFTP in Korea was confirmed using the largest number of cases to date. The introduction of NIFTP may have a small overall impact in Korean practice.
View article: Interobserver and intraobserver variation in the morphological evaluation of noninvasive follicular thyroid neoplasm with papillary‐like nuclear features in Asian practice
Interobserver and intraobserver variation in the morphological evaluation of noninvasive follicular thyroid neoplasm with papillary‐like nuclear features in Asian practice Open
To evaluate the current diagnostic criteria in reporting nuclear features of noninvasive follicular thyroid neoplasm with papillary‐like nuclear features (NIFTP), nine Asian pathologists with expertise in thyroid reviewed virtual slides of…
View article: Clinicopathological and Preclinical Findings of NUT Carcinoma: A Multicenter Study
Clinicopathological and Preclinical Findings of NUT Carcinoma: A Multicenter Study Open
Background NUT carcinoma is a rare aggressive disease caused by BRD4/3-NUT fusion, and C-MYC upregulation plays a key role in the pathogenesis. Here, we report on the clinicopathological characteristics of Korean patients with NUT carcinom…
View article: The prevalence and surgical outcomes of Hürthle cell lesions in FNAs of the thyroid: A multi‐institutional study in 6 Asian countries
The prevalence and surgical outcomes of Hürthle cell lesions in FNAs of the thyroid: A multi‐institutional study in 6 Asian countries Open
Background Hürthle cell‐rich nodules (HCNs) encompass non‐neoplastic to malignant lesions. There is paucity of literature on the frequency distribution of HCNs among Bethesda categories, histologic follow‐up, risk of malignancy (ROM), and …
View article: The Usefulness of Immunocytochemistry of CD56 in Determining Malignancy from Indeterminate Thyroid Fine-Needle Aspiration Cytology
The Usefulness of Immunocytochemistry of CD56 in Determining Malignancy from Indeterminate Thyroid Fine-Needle Aspiration Cytology Open
Using CD56 alone showed relatively low specificity despite high sensitivity for detecting malignancy. Combining CD56 with HBME-1 could increase the specificity. Thus, we suggest that CD56 could be a useful preoperative marker for different…
View article: DNA Mismatch Repair Protein Immunohistochemistry and MLH1 Promotor Methylation Testing for Practical Molecular Classification and the Prediction of Prognosis in Endometrial Cancer
DNA Mismatch Repair Protein Immunohistochemistry and MLH1 Promotor Methylation Testing for Practical Molecular Classification and the Prediction of Prognosis in Endometrial Cancer Open
The incidence of endometrial cancer is rapidly increasing worldwide, and its molecular classification has gained importance for new therapeutic approaches. This study sought to examine the clinicopathologic features and immune markers asso…
View article: Microsatellite Instability and Programmed Cell Death-Ligand 1 Expression in Stage II/III Gastric Cancer
Microsatellite Instability and Programmed Cell Death-Ligand 1 Expression in Stage II/III Gastric Cancer Open
Objective: We investigated microsatellite instability (MSI) status and programed cell death ligand 1 (PD-L1) expression as predictors of prognosis and responsiveness to chemotherapy for stage II/III gastric cancer. Background: The clinical…
View article: Impact of non-invasive follicular thyroid neoplasm with papillary-like nuclear features on the Bethesda system for reporting thyroid cytopathology: a multi-institutional study in five Asian countries
Impact of non-invasive follicular thyroid neoplasm with papillary-like nuclear features on the Bethesda system for reporting thyroid cytopathology: a multi-institutional study in five Asian countries Open
Several Western studies showed that the recent introduction of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) significantly decreased risk of malignancy for cytological diagnostic categories. We aimed…
View article: Ultrasonographic features and clinicopathologic characteristics of macrofollicular variant papillary thyroid carcinoma
Ultrasonographic features and clinicopathologic characteristics of macrofollicular variant papillary thyroid carcinoma Open
Macrofollicular variant papillary thyroid carcinoma (MFV-PTC) is defined as papillary thyroid carcinoma with macrofollicles of >200 μm in more than 50% of the cross-sectional area of the specimen. The aim of this study was to evaluate the …
View article: Preoperative Cytologic Diagnosis of Warthin-like Variant of Papillary Thyroid Carcinoma
Preoperative Cytologic Diagnosis of Warthin-like Variant of Papillary Thyroid Carcinoma Open
The lymphocytic smear pattern and the number of inflammatory cells of WLV-PTC are different from those of PTC-LT or PTC and will be helpful for the differential diagnosis of WLV-PTC in preoperative FNA.
View article: The History of Korean Thyroid Pathology
The History of Korean Thyroid Pathology Open
Pathologists play a critical role in the diagnosis and treatment planning of patients as well as in research. The first article of thyroid related research in Korea was reported in 1911. The Korean Society of Pathologists was found in 1946…
View article: A qualitative study on leadership experiences of women doctors in Korea
A qualitative study on leadership experiences of women doctors in Korea Open
This study was designed to explore women doctors' leadership experiences and to identify mechanisms of leadership development based on their experiences. Between November 1 and December 18, 2017, in-depth interviews were conducted with 12 …
View article: The Use of Fine-Needle Aspiration (FNA) Cytology in Patients with Thyroid Nodules in Asia: A Brief Overview of Studies from the Working Group of Asian Thyroid FNA Cytology
The Use of Fine-Needle Aspiration (FNA) Cytology in Patients with Thyroid Nodules in Asia: A Brief Overview of Studies from the Working Group of Asian Thyroid FNA Cytology Open
Ultrasound-guided fine-needle aspiration (FNA) cytology is the most widely used screening and diagnostic method for thyroid nodules. Although Western guidelines for managing thyroid nodules and the Bethesda System for Reporting Thyroid Cyt…