Long-term biological effect of ¹³¹I-administration shows the appearance of various histological disorders confirmed by disturbances in hepatic and renal functions.

P. graveolens EO has the potential in mitigating most of the adverse effects in the hippocampus and prevents SWM impairment induced by MET toxicity.

Procedures using iodine-131 ( 131 I) represent about 90% of all therapies in nuclear medicine [1, 2]. It is important to evaluate the long-term biological effects of 131 I treatment on non-target organs in order to improve the patient radioprotection. The aim of this work is to use an experimental animal model to contribute to the understanding of some biological effects induced by 131 I contamination, and especially histological effects. Two models of Wistar rats with (Tr+) and without thyroid (Tr-) were orally c…