Saakshi Saini
YOU?
Author Swipe
View article: Development and Evaluation of Indian Mustard Honey-Loaded Fast Dissolving PVA/AG Nanofibers for Enhanced Neuroprotection
Development and Evaluation of Indian Mustard Honey-Loaded Fast Dissolving PVA/AG Nanofibers for Enhanced Neuroprotection Open
Mustard honey (MH) is a rich source of polyphenols, which impart antioxidant, antiapoptotic, and cytoprotective activities in neuronal cells. However, its high-dose requirement for delivering pharmaceutical properties, along with challenge…
View article: A Pyridyl-Benzimidazole Based Ruthenium(II) Complex as Optical Sensor: Targeted Cyanide Detection and Live Cell Imaging Applications
A Pyridyl-Benzimidazole Based Ruthenium(II) Complex as Optical Sensor: Targeted Cyanide Detection and Live Cell Imaging Applications Open
The extreme toxicity of cyanide (\ce{CN^-}) ions in diverse environmental media has garnered significant attention toward the design of well-organized molecular probes for their selective and sensitive detection. In this context, we presen…
View article: Shramahara Mahakasya, a traditional polyherbal formulation, induces anti-anxiety activity in hippocampal neurons by effectuating SOD2-mediated protection against oxidative stress
Shramahara Mahakasya, a traditional polyherbal formulation, induces anti-anxiety activity in hippocampal neurons by effectuating SOD2-mediated protection against oxidative stress Open
Background: Shramahara Mahakasya (SM) is an Ayurvedic polyherbal formulation known for its anti-fatigue and anti-anxiety effects on the human body. However, its mechanism of action remains largely unexplored. In this study, we investigated…
View article: Pterostilbene-Isothiocyanate Inhibits Proliferation of Human MG-63 Osteosarcoma Cells via Abrogating β-Catenin/TCF-4 Interaction─A Mechanistic Insight
Pterostilbene-Isothiocyanate Inhibits Proliferation of Human MG-63 Osteosarcoma Cells via Abrogating β-Catenin/TCF-4 Interaction─A Mechanistic Insight Open
Osteosarcoma, a highly metastasizing bone neoplasm, is a leading cause of death and disability in children and adolescents worldwide. Osteosarcoma is only suboptimally responsive to surgery and radio- and chemotherapy, that too with advers…
View article: Organosulfurs, S-allyl cysteine and N-acetyl cysteine sequester di-carbonyls and reduces carbonyl stress in HT22 cells
Organosulfurs, S-allyl cysteine and N-acetyl cysteine sequester di-carbonyls and reduces carbonyl stress in HT22 cells Open
View article: Pterostilbene–isothiocyanate reduces miR-21 level by impeding Dicer-mediated processing of pre-miR-21 in 5-fluorouracil and tamoxifen-resistant human breast cancer cell lines
Pterostilbene–isothiocyanate reduces miR-21 level by impeding Dicer-mediated processing of pre-miR-21 in 5-fluorouracil and tamoxifen-resistant human breast cancer cell lines Open
View article: Plausible Mechanistic Insights in Biofilm Eradication Potential against <i>Candida</i> spp. Using <i>In Situ</i> -Synthesized Tyrosol-Functionalized Chitosan Gold Nanoparticles as a Versatile Antifouling Coating on Implant Surfaces
Plausible Mechanistic Insights in Biofilm Eradication Potential against <i>Candida</i> spp. Using <i>In Situ</i> -Synthesized Tyrosol-Functionalized Chitosan Gold Nanoparticles as a Versatile Antifouling Coating on Implant Surfaces Open
In the present study, tyrosol-functionalized chitosan gold nanoparticles (Chi-TY-AuNPs) were prepared as an alternative treatment strategy to combat fungal infections. Various biophysical techniques were used to characterize the synthesize…
View article: Plausible Mechanistic Insights in Biofilm Eradication Potential of against <i>Candida</i> spp. using In Situ Synthesized Tyrosol Functionalized Chitosan Gold Nanoparticles as a versatile Antifouling Coating on Implant Surfaces
Plausible Mechanistic Insights in Biofilm Eradication Potential of against <i>Candida</i> spp. using In Situ Synthesized Tyrosol Functionalized Chitosan Gold Nanoparticles as a versatile Antifouling Coating on Implant Surfaces Open
In the present study, tyrosol functionalized chitosan gold nanoparticles (Chi-TY-AuNP’s) were prepared as an alternative treatment strategy to combat fungal infections. Various biophysical techniques were used to characterize the synthesiz…