Sabina De Geest
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View article: Understanding participation of liver transplant recipients in an exercise intervention RCT: a cross-sectional study of barriers and motivators
Understanding participation of liver transplant recipients in an exercise intervention RCT: a cross-sectional study of barriers and motivators Open
NCT06302205 (trial registration date: 06/12/2023).
View article: High Implementation Adherence to Lenalidomide in Multiple Myeloma
High Implementation Adherence to Lenalidomide in Multiple Myeloma Open
Background and Purpose: Adherence to oral anticancer therapy correlates with outcome. Lenalidomide (LEN) is an oral mainstay treatment for multiple myeloma (MM), administered in 21-day/7-day (on/off) cycles. Data on LEN adherence is limite…
View article: Implementation and Effectiveness of an eHealth supported integrated care model for patients after hematopoietic cell transplantation: The Swiss SMILe hybrid effectiveness-implementation RCT
Implementation and Effectiveness of an eHealth supported integrated care model for patients after hematopoietic cell transplantation: The Swiss SMILe hybrid effectiveness-implementation RCT Open
eHealth-supported integrated care models (eICMs) enable early complication management and foster self-management. The SMILe-ICM, an Advanced Practice Nurse (APN)-led eICM for patients after hematopoietic cell transplantation, was previousl…
View article: Accelerating innovation: implementation science as a cornerstone of high-performance Swiss research infrastructures
Accelerating innovation: implementation science as a cornerstone of high-performance Swiss research infrastructures Open
Switzerland invests substantially in research, yet many innovations fail to reach routine healthcare. This paper argues that embedding implementation science into national research infrastructures is key to closing this gap, reducing resea…
View article: Associated Factors to Nonadherence to Routine Appointments after Kidney Transplantation: The ADHERE Brazil Study
Associated Factors to Nonadherence to Routine Appointments after Kidney Transplantation: The ADHERE Brazil Study Open
Rationale Nonadherence to routine outpatient appointments (NApp) post kidney transplantation (KT) is a poorly studied health behavior associated with unfavorable outcomes. In the ADHERE BRAZIL Study, we previously reported a high prevalenc…
View article: Editorial: Living Well After Organ Transplantation
Editorial: Living Well After Organ Transplantation Open
View article: Understanding Participation of Liver Transplant Recipients in an Exercise Intervention RCT: A Cross-sectional Study of Barriers and Motivators
Understanding Participation of Liver Transplant Recipients in an Exercise Intervention RCT: A Cross-sectional Study of Barriers and Motivators Open
Background Understanding barriers to participate in exercise intervention studies is critical for guiding approaches to increase sample representativeness, to mitigate selection bias, and to achieve the required sample size for study purpo…
View article: Invasive Candida infections in solid organ transplant recipients between 2008 and 2020
Invasive Candida infections in solid organ transplant recipients between 2008 and 2020 Open
Contemporary data on the epidemiology and outcomes of invasive candidiasis (IC) in solid organ transplant recipients (SOTr) are limited. This retrospective multicenter cohort study, nested within the Swiss Transplant Cohort Study, describe…
View article: Exploring Stakeholder Involvement in Intervention Implementation Studies: Systematic Evidence Synthesis With an Evidence Gap Map Approach
Exploring Stakeholder Involvement in Intervention Implementation Studies: Systematic Evidence Synthesis With an Evidence Gap Map Approach Open
Stakeholder involvement (SI) is essential for effective and sustainable intervention implementation, yet practical guidance is lacking. This study mapped SI use in implementation science studies, identified gaps, and proposed a practical f…
View article: Exploring participation bias in a home-based exercise and physical activity intervention study among kidney transplant recipients – an observational comparative study
Exploring participation bias in a home-based exercise and physical activity intervention study among kidney transplant recipients – an observational comparative study Open
Background Limited knowledge exists about individuals who decline participation in exercise trials. This study compared characteristics of participants and nonparticipants in a kidney transplant exercise trial using a dual-consent design. …
View article: POS1468-HPR EFFECTIVENESS AND IMPLEMENTATION OF DMARD ADHERENCE INTERVENTIONS IN RHEUMATOID ARTHRITIS: A SYSTEMATIC REVIEW
POS1468-HPR EFFECTIVENESS AND IMPLEMENTATION OF DMARD ADHERENCE INTERVENTIONS IN RHEUMATOID ARTHRITIS: A SYSTEMATIC REVIEW Open
View article: OP0116-HPR EXAMINING RHEUMATOID ARTHRITIS CARE AND eHEALTH SUPPORT IN TWO SWISS CENTRES: A CONTEXTUAL ANALYSIS TO DEVELOP THE SQUEEZE CARE MODEL FOR DMARDS ADHERENCE AND IMPLEMENTATION STRATEGIES
OP0116-HPR EXAMINING RHEUMATOID ARTHRITIS CARE AND eHEALTH SUPPORT IN TWO SWISS CENTRES: A CONTEXTUAL ANALYSIS TO DEVELOP THE SQUEEZE CARE MODEL FOR DMARDS ADHERENCE AND IMPLEMENTATION STRATEGIES Open
View article: POS1461-HPR PREVALENCE AND CORRELATES OF ADHERENCE TO DISEASE MODIFYING ANTIRHEUMATIC DRUGS (DMARDS) IN ADULTS WITH RHEUMATOID ARTHRITIS AND ITS CONSEQUENCES – A SCOPING REVIEW
POS1461-HPR PREVALENCE AND CORRELATES OF ADHERENCE TO DISEASE MODIFYING ANTIRHEUMATIC DRUGS (DMARDS) IN ADULTS WITH RHEUMATOID ARTHRITIS AND ITS CONSEQUENCES – A SCOPING REVIEW Open
View article: POS0490 CHALLENGES IN IMPLEMENTING EVIDENCE-BASED HEALTH INTERVENTIONS IN THE EUROPEAN UNION: THE ROLE OF THE CONTEXTUAL ANALYSIS IN THE SQUEEZE PROJECT
POS0490 CHALLENGES IN IMPLEMENTING EVIDENCE-BASED HEALTH INTERVENTIONS IN THE EUROPEAN UNION: THE ROLE OF THE CONTEXTUAL ANALYSIS IN THE SQUEEZE PROJECT Open
View article: Mortality atlas of the main causes of death for the elderly population (≥75 years) in Switzerland during 2010–2020
Mortality atlas of the main causes of death for the elderly population (≥75 years) in Switzerland during 2010–2020 Open
BACKGROUND: Mortality atlases provide insight into the health burdens a society is facing and help visualise them spatially. Here we estimate the geographical distribution of different mortality causes in the elderly population (≥75 years)…
View article: Self-reported non-adherence to immunosuppressive medication detected by the BAASIS predicts allograft rejections in kidney transplant recipients
Self-reported non-adherence to immunosuppressive medication detected by the BAASIS predicts allograft rejections in kidney transplant recipients Open
Background After kidney transplantation adherence to immunosuppressive medication is crucial for graft survival and its assessment requires valid measurements. The Basel Assessment of Adherence-to Immunosuppressive Medications Scale (BAASI…
View article: Home-based exercise and physical activity intervention after kidney transplantation: impact of exercise intensity (PHOENIX-Kidney). Protocol for a multicentre randomized controlled trial
Home-based exercise and physical activity intervention after kidney transplantation: impact of exercise intensity (PHOENIX-Kidney). Protocol for a multicentre randomized controlled trial Open
Background Cardiovascular (CV) disease represents a leading cause of death in kidney transplant recipients (KTRs). Poor physical fitness adds to the increased CV risk of KTRs. Exercise-based rehabilitation and physical activity interventio…
View article: Implementation and ethical issues of an eHealth-facilitated integrated care model in stem cell transplantation: A qualitative process evaluation study
Implementation and ethical issues of an eHealth-facilitated integrated care model in stem cell transplantation: A qualitative process evaluation study Open
Introduction eHealth-facilitated integrated care models (eICMs) offer promising enhancements to healthcare delivery in stem cell transplantation, but entail implementation and ethical challenges. While qualitative process evaluation method…
View article: Surgical Site Infections, Risk Factors, and Outcomes After Liver Transplant
Surgical Site Infections, Risk Factors, and Outcomes After Liver Transplant Open
Importance Surgical site infections (SSIs) are one of the most common health care–associated infections. Surgical site infections can have harmful effects in liver transplant (LT) recipients. Objective To assess the incidence of SSI after …
View article: Examining Practices Related to Ethical Aspects in eHealth Evaluation Research: Protocol for a Scoping Review
Examining Practices Related to Ethical Aspects in eHealth Evaluation Research: Protocol for a Scoping Review Open
Background eHealth technologies, including remote patient monitoring (RPM) applications, have the potential to improve care for diseases such as cancer and cardiovascular conditions. However, they also raise ethical aspects that are often …
View article: Home-based exercise and PHysical activity maintenance interventiOn after livEr traNsplantation: Impact of eXercise intensity (PHOENIX-Liver)
Home-based exercise and PHysical activity maintenance interventiOn after livEr traNsplantation: Impact of eXercise intensity (PHOENIX-Liver) Open
Liver transplant recipients experience comorbidities, including impaired physical fitness, which could be managed by exercise and physical activity interventions. This study aims to evaluate the feasibility, clinical effectiveness and cost…
View article: Evaluating the cost, cost-effectiveness and survival of an eHealth-facilitated integrated care model for allogeneic stem cell transplantation: Results of the German SMILe randomized, controlled implementation science trial
Evaluating the cost, cost-effectiveness and survival of an eHealth-facilitated integrated care model for allogeneic stem cell transplantation: Results of the German SMILe randomized, controlled implementation science trial Open
View article: Reintegration Into the Workforce After Kidney Transplantation Based on Urbanization Status in Switzerland
Reintegration Into the Workforce After Kidney Transplantation Based on Urbanization Status in Switzerland Open
Patient and graft outcomes were favorable, with improved work reintegration observed at the 1-year mark post-KT for recipients from rural backgrounds compared to those from suburban and urban areas.
View article: How pharma can amplify product value with implementation science
How pharma can amplify product value with implementation science Open
Achieving blockbuster status requires more than clinical trial success. Crucial barriers often include real-world factors like patient acceptance, prescriber behavior and timely and full reimbursement. Implementation science can be used to…
View article: International Variability of Barriers to Adherence to Immunosuppressive Medication in Adult Heart Transplant Recipients. A Secondary Data Analysis of the BRIGHT Study
International Variability of Barriers to Adherence to Immunosuppressive Medication in Adult Heart Transplant Recipients. A Secondary Data Analysis of the BRIGHT Study Open
Non-adherence to immunosuppressive medication among transplant patients is associated with poor clinical outcomes and higher economic costs. Barriers to immunosuppressives are a proximal determinant of non-adherence. So far, international …
View article: Characteristics and Activities of Nurses in Expanded Roles Employed in Swiss Nursing Homes: A Cross‐Sectional Study
Characteristics and Activities of Nurses in Expanded Roles Employed in Swiss Nursing Homes: A Cross‐Sectional Study Open
Background As the number of nursing home residents with multiple healthcare needs grows, the demand for nursing expertise increases. The implementation of new care models involving nurses with expanded roles is crucial for ensuring quality…
View article: Mapping implementation strategies to reach community-dwelling older adults in Northwest Switzerland
Mapping implementation strategies to reach community-dwelling older adults in Northwest Switzerland Open
Background In Northwestern Switzerland, recent legislation tackles the needs of community-dwelling older adults by creating Information and Advice Centers (IACs). IACs are a new service in the community that aims to assess the needs and pr…
View article: Current use and openness to use assistive technologies among home-dwelling elders in Switzerland: a cross-sectional study
Current use and openness to use assistive technologies among home-dwelling elders in Switzerland: a cross-sectional study Open
View article: Antibody and T-Cell Response to Bivalent Booster SARS-CoV-2 Vaccines in People With Compromised Immune Function: COVERALL-3 Study
Antibody and T-Cell Response to Bivalent Booster SARS-CoV-2 Vaccines in People With Compromised Immune Function: COVERALL-3 Study Open
Background Bivalent messenger RNA (mRNA) vaccines, designed to combat emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, incorporate ancestral strains and a new variant. Our study assessed the immune response i…
View article: #3028 Predictive validity of the Basel Assessment of Adherence to Immunosuppressive Medication Scale (BAASIS©) after renal transplantation
#3028 Predictive validity of the Basel Assessment of Adherence to Immunosuppressive Medication Scale (BAASIS©) after renal transplantation Open
Background and Aims Adherence towards immunosuppressive medication is crucial for allograft survival after renal transplantation. However, its assessment in daily clinical practice remains challenging. The BAASIS© questionnaire, is a valid…