Sabine E. Kulling
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View article: Method development and validation for quantitative determination of urinary biomarkers of food intake for multiple foods
Method development and validation for quantitative determination of urinary biomarkers of food intake for multiple foods Open
Biomarkers of food intake (BFIs) have emerged as a promising objective tool to complement traditional self-reported dietary assessment in nutritional research, with the potential to reduce systematic errors and improve accuracy. The develo…
View article: Influence of hydroponic cultivation subsystems on vegetative growth, vigour, and metabolite profiles in vanilla
Influence of hydroponic cultivation subsystems on vegetative growth, vigour, and metabolite profiles in vanilla Open
Vanilla, a high-value crop, faces numerous cultivation challenges, with global demand far outpacing supply. The absence of standardized cultivation practices underscores the need for innovative solutions. This study explores the vegetative…
View article: Sustainable and Resilient Agrifood Systems (<scp>SARAS</scp>). A Leibniz Position
Sustainable and Resilient Agrifood Systems (<span>SARAS</span>). A Leibniz Position Open
Current agrifood systems fail to provide healthy, affordable food for all while also damaging the environment, contributing to climate change, reducing biodiversity, and increasing inequality. Given these compounding crises, it is crucial …
View article: Development of an Untargeted Method for the Analysis of the Volatile Profile of Onions via Solid‐Phase Microextraction Arrow‐Headspace‐Gas Chromatography‐Mass Spectrometry Using Design of Experiments
Development of an Untargeted Method for the Analysis of the Volatile Profile of Onions via Solid‐Phase Microextraction Arrow‐Headspace‐Gas Chromatography‐Mass Spectrometry Using Design of Experiments Open
The distinctive aroma of onions, consisting primarily of sulfur‐containing compounds, is one of the reasons for the popularity of the vegetable. The rapid enzymatic and chemical reactions that occur after the destruction of onion bulb tiss…
View article: Opinion Piece: New Plant‐Based Food Products Between Technology and Physiology
Opinion Piece: New Plant‐Based Food Products Between Technology and Physiology Open
The rapid growth of product sectors for plant‐based meat and dairy alternatives has raised significant scientific interest in their nutritional and ecological benefits. Here, it outlines the fractionation of plant‐based raw materials and d…
View article: Comparative analysis of the genomes and aflatoxin production patterns of three species within the Aspergillus section Flavi reveals an undescribed chemotype and habitat-specific genetic traits
Comparative analysis of the genomes and aflatoxin production patterns of three species within the Aspergillus section Flavi reveals an undescribed chemotype and habitat-specific genetic traits Open
Aflatoxins are the most dangerous mycotoxins for food safety. They are mainly produced by Aspergillus flavus , A. parasiticus , and A. minisclerotigenes . The latter, an understudied species, was the main culprit for outbreaks of fatal afl…
View article: Comprehensive metabolome characterization of leaves, internodes, and aerial roots of <scp><i>Vanilla planifolia</i></scp> by untargeted LC–MS and GC × GC–MS
Comprehensive metabolome characterization of leaves, internodes, and aerial roots of <span><i>Vanilla planifolia</i></span> by untargeted LC–MS and GC × GC–MS Open
Introduction Untargeted metabolomics is a powerful tool that provides strategies for gaining a systematic understanding of quantitative changes in the levels of metabolites, especially when combining different metabolomic platforms. Vanill…
View article: The Tale of Two Ions Na+ and Cl- : Unraveling Onion Plant Responses to Varying Salt Treatments
The Tale of Two Ions Na+ and Cl- : Unraveling Onion Plant Responses to Varying Salt Treatments Open
Background Exploring the adaptive responses of onions (Allium cepa L.) to salinity reveals a critical challenge for this salt-sensitive crop. While previous studies have concentrated on the effects of sodium (Na+), this research highlights…
View article: Controversy on health-based guidance values for bisphenol A—the need of criteria for studies that serve as a basis for risk assessment
Controversy on health-based guidance values for bisphenol A—the need of criteria for studies that serve as a basis for risk assessment Open
Since 2006, the responsible regulatory bodies have proposed five health-based guidance values (HBGV) for bisphenol A (BPA) that differ by a factor of 250,000. This range of HBGVs covers a considerable part of the range from highly toxic to…
View article: Correction: Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food
Correction: Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food Open
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View article: Effects of pectin methyl-esterification on intestinal microbiota and its immunomodulatory properties in naive mice
Effects of pectin methyl-esterification on intestinal microbiota and its immunomodulatory properties in naive mice Open
Pectins are dietary fibers that are attributed with several beneficial immunomodulatory effects. Depending on the degree of esterification (DE), pectins can be classified as high methoxyl pectin (HMP) or low methoxyl pectin (LMP). The aim …
View article: Acetaldehyde as a Food Flavoring Substance: Aspects of Risk Assessment
Acetaldehyde as a Food Flavoring Substance: Aspects of Risk Assessment Open
The Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG) has reviewed the currently available data in order to assess the health risks associated with the use of acetaldehyde as a flavoring substance in foods. Ac…
View article: A Systematic Review and Comprehensive Evaluation of Human Intervention Studies to Unravel the Bioavailability of Hydroxycinnamic Acids
A Systematic Review and Comprehensive Evaluation of Human Intervention Studies to Unravel the Bioavailability of Hydroxycinnamic Acids Open
Significance: Hydroxycinnamic acids (HCAs) are the main phenolic acids in the western diet. Harmonizing the available information on the absorption, distribution, metabolism, and excretion (ADME) of HCAs is fundamental to unraveling the co…
View article: Microbial Metabolism of the Soy Isoflavones Daidzein and Genistein in Postmenopausal Women: Human Intervention Study Reveals New Metabotypes
Microbial Metabolism of the Soy Isoflavones Daidzein and Genistein in Postmenopausal Women: Human Intervention Study Reveals New Metabotypes Open
Background: Soy isoflavones belong to the group of phytoestrogens and are associated with beneficial health effects but are also discussed to have adverse effects. Isoflavones are intensively metabolized by the gut microbiota leading to me…
View article: Rathayibacter rubneri sp. nov. isolated from Allium cepa var. Rijnsburger, an onion landrace
Rathayibacter rubneri sp. nov. isolated from Allium cepa var. Rijnsburger, an onion landrace Open
The novel, aerobic, Gram-stain-positive, rod-shaped bacterial strain, ZW T2_19 T , was isolated from an onion sample ( Allium cepa var. Rijnsburger). Analyses of the 16S rRNA gene sequence revealed that ZW T2_19 T represented a member of t…
View article: Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis
Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis Open
This systematic review summarizes findings from human studies investigating the different routes of absorption, metabolism, distribution and excretion (ADME) of dietary flavan-3-ols and their circulating metabolites in healthy subjects. Li…
View article: Dynamics and determinants of human plasma bile acid profiles during dietary challenges
Dynamics and determinants of human plasma bile acid profiles during dietary challenges Open
In recent years, bile acids (BA) have received great interest due to their pleiotropic biological activity and the presence of plasma membrane-bound and nuclear receptors. Moreover, BA in blood have been identified by metabolite screening …
View article: Plasma Metabolic Signatures of Healthy Overweight Subjects Challenged With an Oral Glucose Tolerance Test
Plasma Metabolic Signatures of Healthy Overweight Subjects Challenged With an Oral Glucose Tolerance Test Open
Insulin secretion following ingestion of a carbohydrate load affects a multitude of metabolic pathways that simultaneously change direction and quantity of interorgan fluxes of sugars, lipids and amino acids. In the present study, we aimed…
View article: Formation of B- and M-group aflatoxins and precursors by Aspergillus flavus on maize and its implication for food safety
Formation of B- and M-group aflatoxins and precursors by Aspergillus flavus on maize and its implication for food safety Open
Aflatoxins count to the most toxic known mycotoxins and are a threat to food safety especially in regions with a warm and humid climate. Contaminated food reaches consumers globally due to international trade, leading to stringent regulato…
View article: Metabolism of Daidzein and Genistein by Gut Bacteria of the Class Coriobacteriia
Metabolism of Daidzein and Genistein by Gut Bacteria of the Class Coriobacteriia Open
The intake of isoflavones is presumed to be associated with health benefits in humans, but also potential adverse effects of isoflavones are controversially discussed. Isoflavones can be metabolized by gut bacteria leading to modulation of…
View article: Adlercreutzia rubneri sp. nov., a resveratrol-metabolizing bacterium isolated from human faeces and emended description of the genus Adlercreutzia
Adlercreutzia rubneri sp. nov., a resveratrol-metabolizing bacterium isolated from human faeces and emended description of the genus Adlercreutzia Open
The novel, anaerobic, Gram-positive, rod-shaped bacterial strain, ResAG-91 T , was isolated from a faecal sample of a male human volunteer. Analysis of the 16S rRNA gene sequence revealed that strain ResAG-91 T showed high similarity to th…