Sabrina Commeyne
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Author Swipe
View article: Drug Shortages in a Pediatric Stem Cell Transplantation Unit: A 5-Year Analysis of Incidences and Solutions
Drug Shortages in a Pediatric Stem Cell Transplantation Unit: A 5-Year Analysis of Incidences and Solutions Open
Background: Drug shortages cause numerous difficulties for clinicians, pharmacists, patients and healthcare authorities worldwide. The last decade, different therapeutic classes essential during conditioning regimens and supportive care in…
View article: Population pharmacokinetics of cefazolin before, during and after cardiopulmonary bypass to optimize dosing regimens for children undergoing cardiac surgery
Population pharmacokinetics of cefazolin before, during and after cardiopulmonary bypass to optimize dosing regimens for children undergoing cardiac surgery Open
We propose an optimized dosing regimen for cefazolin during cardiac surgery in paediatric patients to avoid treatment failure due to inadequate antibiotic prophylaxis.
View article: Impact of vancomycin protein binding on target attainment in critically ill children: back to the drawing board?
Impact of vancomycin protein binding on target attainment in critically ill children: back to the drawing board? Open
The protein binding of vancomycin in our paediatric population was lower than reported in non-critically ill adults and exhibited large variability. Higher target attainment rates were achieved when using PK/PD indices based on unbound con…