Sophie Testa
YOU?
Author Swipe
View article: Practical Suggestions for an Optimal Management of Vitamin K Antagonists: Italian Federation of Centers for the Diagnosis of Thrombotic Disorders and the Surveillance of the Antithrombotic Therapies (FCSA) Position Paper
Practical Suggestions for an Optimal Management of Vitamin K Antagonists: Italian Federation of Centers for the Diagnosis of Thrombotic Disorders and the Surveillance of the Antithrombotic Therapies (FCSA) Position Paper Open
In the era of direct oral anticoagulants, vitamin K antagonists retain a clinically relevant role in thrombotic disorders. In Italy, approximately 20% of the patients on anticoagulant therapies receives a VKA, in most cases warfarin. The o…
View article: STRESS–INDUCIBLE MYOCARDIAL ISCHEMIA DUE TO A VENTRICULO–CORONARY FISTULA: WHAT WE KNOW
STRESS–INDUCIBLE MYOCARDIAL ISCHEMIA DUE TO A VENTRICULO–CORONARY FISTULA: WHAT WE KNOW Open
Coronary fistulas represent communications that form between the coronary arteries and a heart chamber or a large vessel. The real incidence is not known as well as their real clinical impact. Typically congenital, they can also develop fo…
View article: A RARE CASE OF ACUTE BIVENTRICULAR DYSFUNCTION IN SYSTEMIC SCLEROSIS
A RARE CASE OF ACUTE BIVENTRICULAR DYSFUNCTION IN SYSTEMIC SCLEROSIS Open
Systemic sclerosis (SSc) is a rare immune–mediated rheumatic disease characterized by diffuse vasculopathy leading to multiorgan fibrosis. We report the case of a 61–year–old man who was diagnosed with SSc one year before. At the time of d…
View article: PERMANENT JUNCTIONAL RECIPROCATING TACHYCARDIA: IT IS IMPORTANT TO KNOW HOW TO RECOGNIZE IT
PERMANENT JUNCTIONAL RECIPROCATING TACHYCARDIA: IT IS IMPORTANT TO KNOW HOW TO RECOGNIZE IT Open
Permanent junctional reciprocating tachycardia, also known as Coumel‘s tachycardia, is a rare form of supraventricular tachycardia that is usually incessant, characterised by retrograde conduction via an accessory pathway usually located i…
View article: MACHINE LEARNING APPROACH FOR PREDICTION OF CLINICAL OUTCOMES IN ANTICOAGULATED PATIENTS WITH ATRIAL FIBRILLATION
MACHINE LEARNING APPROACH FOR PREDICTION OF CLINICAL OUTCOMES IN ANTICOAGULATED PATIENTS WITH ATRIAL FIBRILLATION Open
Background Despite the availability of different risk scores, the accuracy of actual prediction tools for outcomes in patients with atrial fibrillation (AF) remains modest. Although Machine Learning (ML) has been used to predict outcomes i…
View article: SEVERE MITRAL INSUFFICIENCY FROM RHEUMATIC DISEASE: A CASE REPORT
SEVERE MITRAL INSUFFICIENCY FROM RHEUMATIC DISEASE: A CASE REPORT Open
Acute rheumatic fever continues to be a major health problem in many parts of thw world. It’s more common in low–income or developing parts of the world. Antibiotics for bacterial infections may not be available in these areas. In develope…
View article: AUTOIMMUNE MYOCARDITIS IN MELANOMA IMMUNOTHERAPY–COMPLEX CLINICA PRESENTATION AND ADVERSE THERAPEUTIC RESPONSE
AUTOIMMUNE MYOCARDITIS IN MELANOMA IMMUNOTHERAPY–COMPLEX CLINICA PRESENTATION AND ADVERSE THERAPEUTIC RESPONSE Open
A 68–year–old Caucasian female presented to the ED with cardiac chest pain and dyspnea. The patient had a history of arterial hypertension and was equipped with a biventricular pacemaker due to atrial fibrillation with low ventricular resp…
View article: Inappropriate Underdosing of Direct Oral Anticoagulants in Atrial Fibrillation Patients: Results from the START2-AF Registry
Inappropriate Underdosing of Direct Oral Anticoagulants in Atrial Fibrillation Patients: Results from the START2-AF Registry Open
Background: Direct oral anticoagulants (DOACs) are recommended for stroke prevention in non-valvular atrial fibrillation (NVAF) patients. We aimed to describe the prevalence of inappropriate DOACs dose prescription in the START2-AF Registr…
View article: Long-Term Outcomes in Two-Year Follow-Up after Primary Treatment in Patients with a Prior Venous Thromboembolic Event: A Prospective, Observational, Real-Life Study
Long-Term Outcomes in Two-Year Follow-Up after Primary Treatment in Patients with a Prior Venous Thromboembolic Event: A Prospective, Observational, Real-Life Study Open
Background: Patients with acute venous thromboembolism (VTE) need anticoagulation (AC) therapy for at least 3/6 months (primary treatment); after that period, they should receive a decision on the duration of therapy. Methods: This study e…
View article: Thrombotic events associated with low baseline direct oral anticoagulant levels in atrial fibrillation: the MAS study
Thrombotic events associated with low baseline direct oral anticoagulant levels in atrial fibrillation: the MAS study Open
Although effective and safe, treatment with direct oral anticoagulants (DOAC) in atrial fibrillation (AF) is still associated with thrombotic complications. Whether the measurement of DOAC levels may improve treatment efficacy is an open i…
View article: LOW LEVELS OF DIRECT ORAL ANTICOAGULANTS AT STEADY STATE IN ATRIAL FIBRILLATION PATIENTS WHO LATER DEVELOP THROMBOTIC COMPLICATIONS; THE PROSPECTIVE MAS (MEASURE AND SEE) STUDY
LOW LEVELS OF DIRECT ORAL ANTICOAGULANTS AT STEADY STATE IN ATRIAL FIBRILLATION PATIENTS WHO LATER DEVELOP THROMBOTIC COMPLICATIONS; THE PROSPECTIVE MAS (MEASURE AND SEE) STUDY Open
Background Though effective and safe, treatment with direct oral anticoagulants (DOAC) in atrial fibrillation (AF) is still associated with thrombotic complications. Whether the measurement of DOAC levels may improve the efficacy of treatm…
View article: Fever of Unknown Origin in Children: The Challenge of History Taking
Fever of Unknown Origin in Children: The Challenge of History Taking Open
A fever of unknown origin (FUO) in children is usually described as a fever of at least 8 days duration with no apparent diagnosis after initial investigations, including taking medical history and preliminary laboratory assessment. Infect…
View article: Genomic epidemiology of the main SARS‐CoV‐2 variants in Italy between summer 2020 and winter 2021
Genomic epidemiology of the main SARS‐CoV‐2 variants in Italy between summer 2020 and winter 2021 Open
Since the beginning of the pandemic, SARS‐CoV‐2 has shown a great genomic variability, resulting in the continuous emergence of new variants that has made their global monitoring and study a priority. This work aimed to study the genomic h…
View article: Genomic epidemiology of the main SARS-CoV-2 variants circulating in Italy in 2020 and 2022 period
Genomic epidemiology of the main SARS-CoV-2 variants circulating in Italy in 2020 and 2022 period Open
Since the beginning of the pandemic, SARS-CoV-2 has shown a great genomic variability, resulting in the continuous emergence of new variants that has made their global monitoring and study a priority. This work aimed to study the genomic h…
View article: Management of anticoagulation in atrial fibrillation patients in Italy: insight from the <i>Atrial Fibrillation-Survey on Anticoagulated Patients Register</i> (AF-START)
Management of anticoagulation in atrial fibrillation patients in Italy: insight from the <i>Atrial Fibrillation-Survey on Anticoagulated Patients Register</i> (AF-START) Open
The survey on anticoagulated patients register (START-Register) is an independent, prospective, inception-cohort observational study aimed at providing information on patients on vitamin K antagonists (VKAs) or direct oral anticoagulants (…
View article: P9 INCESSANT ARRHYTHMIC STORM, EFFECTIVELY TREATED BY VENTRICULOPLASTY
P9 INCESSANT ARRHYTHMIC STORM, EFFECTIVELY TREATED BY VENTRICULOPLASTY Open
Arrhythmic storm is an emergency characterized by cardiac electrical instability leading to multiple episodes of sustained ventricular arrhythmias in a short period of time. Patients have multiple comorbidities that require multidisciplina…
View article: P377 PERCUTANEOUS TREATMENT OF INTERMEDIATE AND HIGH–RISK PULMONARY EMBOLISM: A CASE REPORT
P377 PERCUTANEOUS TREATMENT OF INTERMEDIATE AND HIGH–RISK PULMONARY EMBOLISM: A CASE REPORT Open
Pulmonary embolism is the third most frequent cardiovascular pathology, with an incidence of 100–200 cases for 100.000 inhabitants and is one of the main causes of mortality, morbidity and hospitalizations. Systematic thrombolysis represen…
View article: P194 DESTRUCTIVE AORTIC VALVE ENDOCARDITIS WITH INVOLVEMENT OF THE MITRO–AORTIC CURTAIN: A SUCCESSFUL “UFO” PROCEDURE
P194 DESTRUCTIVE AORTIC VALVE ENDOCARDITIS WITH INVOLVEMENT OF THE MITRO–AORTIC CURTAIN: A SUCCESSFUL “UFO” PROCEDURE Open
Infective endocarditis is a relatively rare disease with an estimated mean incidence of 3.6–7.0 cases per 100,000 subject–years. Aortic bicuspid disease, the most frequent congenital anomaly, is one of the main risk factors. Heart failure,…
View article: Attitude to clinical research among health professionals affiliated with the Italian Federation of Centers for the Diagnosis of Thrombotic Disorders and the Surveillance of the Antithrombotic Therapies (FCSA)
Attitude to clinical research among health professionals affiliated with the Italian Federation of Centers for the Diagnosis of Thrombotic Disorders and the Surveillance of the Antithrombotic Therapies (FCSA) Open
Clinical research is vital in supporting evidence-based practice. However, several barriers make participation in research difficult. We performed a survey to evaluate the attitude to research of the members of the Italian Anticoagulation …
View article: Evaluation of Coaguchek<sup>® </sup>Pro II coagulation testing device performance to assess direct oral anticoagulant action. The DOAC-CHECK study
Evaluation of Coaguchek<sup>® </sup>Pro II coagulation testing device performance to assess direct oral anticoagulant action. The DOAC-CHECK study Open
Direct oral anticoagulants (DOAC) measurement is recommended in specific conditions. A point-of-care testing should be used in emergency to qualitatively rule out relevant DOAC concentrations. The DOAC-CHECK Study aims to evaluate whether …
View article: COVID-19 pandemic affects the ability of negative D-dimer to identify venous thromboembolism patients at low risk of recurrence: insights from the Apidulcis study
COVID-19 pandemic affects the ability of negative D-dimer to identify venous thromboembolism patients at low risk of recurrence: insights from the Apidulcis study Open
Not available.
View article: Epidemiological and Clinical Features of SARS-CoV-2 Variants Circulating between April–December 2021 in Italy
Epidemiological and Clinical Features of SARS-CoV-2 Variants Circulating between April–December 2021 in Italy Open
SARS-CoV-2 is constantly evolving, leading to new variants. We analysed data from 4400 SARS-CoV-2-positive samples in order to pursue epidemiological variant surveillance and to evaluate their impact on public health in Italy in the period…