Sabrina Zequeira
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View article: Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects
Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects Open
With increased legalization of recreational and medical cannabis, use of this drug is growing rapidly among older adults. As cannabis use can impair cognition in young adults, it is critically important to understand how consumption intera…
View article: EFFECTS OF ACUTE AND CHRONIC CANNABIS/CANNABINOIDS ON COGNITIVE FUNCTION ACROSS THE LIFESPAN
EFFECTS OF ACUTE AND CHRONIC CANNABIS/CANNABINOIDS ON COGNITIVE FUNCTION ACROSS THE LIFESPAN Open
Cannabis and cannabinoids such as THC (the major psychoactive component of cannabis) tend to impair cognitive performance, but almost all research on this topic has been conducted in young adults. Given that many aged individuals already e…
View article: Pharmacokinetics of delta-9-tetrahydrocannabinol following acute cannabis smoke exposure in mice; effects of sex, age, and strain
Pharmacokinetics of delta-9-tetrahydrocannabinol following acute cannabis smoke exposure in mice; effects of sex, age, and strain Open
Increased use of cannabis and cannabinoids for recreational and medical purposes has led to a growth in research on their effects in animal models. The majority of this work has employed cannabinoid injections; however, smoking remains the…
View article: Touchscreen-Based Cognitive Training Alters Functional Connectivity Patterns in Aged But Not Young Male Rats
Touchscreen-Based Cognitive Training Alters Functional Connectivity Patterns in Aged But Not Young Male Rats Open
Age-related cognitive decline is related to cellular and systems-level disruptions across multiple brain regions. Because age-related cellular changes within different structures do not show the same patterns of dysfunction, interventions …
View article: Age-related impairments on the touchscreen paired associates learning (PAL) task in male rats
Age-related impairments on the touchscreen paired associates learning (PAL) task in male rats Open
View article: Rodent mnemonic similarity task performance requires the prefrontal cortex
Rodent mnemonic similarity task performance requires the prefrontal cortex Open
Mnemonic similarity task performance, in which a known target stimulus must be distinguished from similar lures, is supported by the hippocampus and perirhinal cortex. Impairments on this task are known to manifest with advancing age. Inte…
View article: Rodent mnemonic similarity task performance requires the prefrontal cortex
Rodent mnemonic similarity task performance requires the prefrontal cortex Open
Mnemonic similarity task performance, in which a known target stimulus must be distinguished from similar lures, is supported by the hippocampus and perirhinal cortex and is known to decline in advanced age. Interestingly, disrupting hippo…