Explanipedia

Neocarya macrophylla ethyl acetate fraction attenuates oxidative stress and inflammation in high-fat diet and streptozotocin-induced diabetic rats Open

Sadiq Maifata, Abdullahi Adamu Ja'e, Aminat Anura, Aminat Suleman-Alabi, Chinedu Onwuchekwa , et al. · 2025

Oxidative stress and inflammation drive diabetes. Conventional treatments inadequately target these. Neocarya macrophylla shows preliminary antioxidant promise. This study aims to investigate its antioxidant and anti-inflammatory effects i…

Exploring the Antidiabetic Potential of Neocarya macrophylla (Nm) Leaf Fractions: A Comprehensive Study on Hypoglycemic Activity, Body Mass Index, and Hematological Parameters in High-Fat Diet/ Streptozotocin-Induced Diabetic Rat Open

Sadiq Maifata, Amina Jega Yusuf, Zayyanu Umar Usman, A.M. Rabiu, Abdullahi Adamu Ja'e , et al. · 2024

The prevalence of diabetes mellitus (DM) continues to rise globally, posing significant health challenges and burdens. This metabolic disorder, characterized by elevated blood glucose levels, contributes to various complications including …

Prevalence and Pattern of Glomerulonephritis: An Experience of Two Tertiary Centers in Malaysia Open

Sadiq Maifata, Rafidah Hod, Fauzah Abd Ghani, Nor Fadhlina Zakaria · 2023

The prevalence of glomerulonephritis (GN), especially membranous GN (MGN), changes from time to time. This change may be due to genetic predisposition, environmental factors race, age, and indications for a renal biopsy. This study was con…

Membranous Glomerulonephritis: A Retrospective Study on Prognostic Outcome Open

Sadiq Maifata, Fauzah Abd Ghani, Rafidah Hod, Nor Fadhlina Zakaria · 2022

Background: Membranous glomerulonephritis (MGN) is one of the most common causes of nephrotic syndrome in non-diabetic adults, accounting for up to one-third of biopsy diagnostics in some regions. A watchful waiting strategy has been adopt…

Membranous glomerulonephritis: a retrospective study on prognostic outcome Open

Sadiq Maifata, Rafidah Hod, Nor Fadhlina Zakaria, Fauzah Abd Ghani · 2021

Background: Membranous glomerulonephritis (MGN) is one of the most common causes of nephrotic syndrome in non-diabetic adults, accounting for up to one-third of biopsy diagnostics in some regions. A watchful waiting strategy has been adopt…

Membranous Glomerulonephritis: Role of Retinol-Binding Protein in Monitoring and Prognostication Open

Sadiq Maifata, Fauzah Abd Ghani, Rafidah Hod, Nor Fadhlina Zakaria · 2021

Initially, retinol-binding protein (RBP), was thought to be a biomarker for proximal convoluted tubule dysfunction could be important in chronic kidney diseases (CKD). Membranous glomerulonephritis (MGN) is an important cause of CKD and en…

RETRACTED: Role of Serum and Urine Biomarkers (PLA2R and THSD7A) in Diagnosis, Monitoring and Prognostication of Primary Membranous Glomerulonephritis Open

Sadiq Maifata, Rafidah Hod, Nor Fadhlina Zakaria, Fauzah Abd Ghani · 2020

Differentiating primary and secondary membranous glomerulonephritis (MGN) using biomarkers for MGN is essential in patients’ diagnosis, treatment and follow-up. Although biopsy has been the primary tool in making the diagnosis, not all pat…

Primary Membranous Glomerulonephritis: The Role of Serum and Urine Biomarkers in Patient Management Open

Sadiq Maifata, Rafidah Hod, Nor Fadhlina Zakaria, Fauzah Abd Ghani · 2019

The detection of phospholipase A2 receptor (PLA2R) and thrombospondin domain containing 7A THSD7A among primary membranous glomerulonephritis (MGN) patients transformed the diagnosis, treatment monitoring, and prognosis. Anti-PLA2R can be …

Membranous Glomerulonephritis: Overview of the Role of Serum and Urine Biomarkers in the Management Open

Sadiq Maifata, Rafidah Hod, Nor Fadhina Zakaria, Fauzah Abd Ghani · 2019

Detection of PLA2R and THSD7A among primary membranous glomerulonephritis (MGN) patients transformed the diagnosis, treatment monitoring and prognosis. Anti-PLA2R can be detected in 70-90% of primary MGN patients while anti-THSD7A in 2-3% …

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