Saeed Alshahrani
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View article: Integrating all Assisting Specialties with Health Administration Practices to Achieve Excellence in Healthcare Quality
Integrating all Assisting Specialties with Health Administration Practices to Achieve Excellence in Healthcare Quality Open
The pursuit of excellence in healthcare quality is perpetually challenged by systemic fragmentation, where siloed operations among critical departments like Nursing, Radiology, and Health Administration lead to communication breakdowns, cl…
View article: Cancer research in Saudi Arabia: A cross-sectional mapping study of historical growth, thematic analysis, collaboration patterns, and future directions
Cancer research in Saudi Arabia: A cross-sectional mapping study of historical growth, thematic analysis, collaboration patterns, and future directions Open
Cancer is a growing health burden in Saudi Arabia, necessitating targeted research to improve its prevention, diagnosis, and treatment. This study aims to map Saudi Cancer Research (SCR) trends, productivity, thematic evolution, collaborat…
View article: ANALYZING THE INTEGRATION OF MEDICAL STAFF MENTAL HEALTH SERVICES INTO PEDIATRIC CARE: A SYSTEMATIC REVIEW
ANALYZING THE INTEGRATION OF MEDICAL STAFF MENTAL HEALTH SERVICES INTO PEDIATRIC CARE: A SYSTEMATIC REVIEW Open
Background: Pediatric mental health disorders are prevalent and under-treated, with integration of behavioral health into pediatric care emerging as a promising strategy to improve access and outcomes. This review synthesizes empirical evi…
View article: Clinical Frontiers of Exosome Research: A Comprehensive Analysis of Human Trials in Diagnostics, Therapeutics, and Regenerative Medicine
Clinical Frontiers of Exosome Research: A Comprehensive Analysis of Human Trials in Diagnostics, Therapeutics, and Regenerative Medicine Open
Background Exosomes, key mediators of intercellular communication, transport functional biomolecules, making them promising tools for diagnostics and therapeutics across various human diseases. Purpose To systematically review and analyze …
View article: Glioma and technology-assisted neurosurgical innovation: a bibliometric study
Glioma and technology-assisted neurosurgical innovation: a bibliometric study Open
View article: Fetal Exposure to Anti-Hypersensitive Drug, Zestoretic Delays Estrus Cycle and Suppresses Female Reproductive Potential in Rats at Their Adulthood
Fetal Exposure to Anti-Hypersensitive Drug, Zestoretic Delays Estrus Cycle and Suppresses Female Reproductive Potential in Rats at Their Adulthood Open
The current investigation is designed to explore the possible role of fetal exposure to the anti-hypersensitive drug zestoretic, a version of lisinopril (angiotensin-converting enzyme inhibitor) and hydrochlorothiazide (a diuretic drug) on…
View article: Melatonin Rescues Renal Mitochondria From Multiple Stressors–Induced Oxidative Stress
Melatonin Rescues Renal Mitochondria From Multiple Stressors–Induced Oxidative Stress Open
The renal system is a significant organ system vulnerable to stress due to its physiological function of toxin elimination. Exposure to a wide array of xenobiotics in humans causes deleterious effects in the kidneys. In the present study, …
View article: Innovative bioaerogels from marine waste and <i>Nephelium lappaceum</i> leaf extract: A multifunctional biomaterial for biomedical and cosmetics
Innovative bioaerogels from marine waste and <i>Nephelium lappaceum</i> leaf extract: A multifunctional biomaterial for biomedical and cosmetics Open
This study explores the fabrication and characterization of chitosan/gelatin (CS/G) bioaerogels loaded with Rambutan Leaf Extract (RLE) for antibacterial and biocompatible applications. Chitosan was initially extracted from shrimp waste, a…
View article: Prevalence of Biofilm Formation Genes in Association with Resistance Phenotypes Among <i>Pseudomonas aeruginosa</i> Clinical Isolates
Prevalence of Biofilm Formation Genes in Association with Resistance Phenotypes Among <i>Pseudomonas aeruginosa</i> Clinical Isolates Open
Background: The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of Pseudomonas aeruginosa represents a significant challenge to current antibiotic therapies, particularly in immunocompromised patients, l…
View article: The role of Saudi universities in facilitating the understanding of national dialects A critical statistical study
The role of Saudi universities in facilitating the understanding of national dialects A critical statistical study Open
This study explores the role of Saudi universities in helping non-Arabic speakers understand national dialects. A descriptive analytical approach was used, focusing on a random sample of students learning Arabic as a second language. The k…
View article: <scp>FIC Domain Protein Adenylyltransferase (FICD)</scp>‐Related Complex Hereditary Spastic Paraplegia with Diabetes Mellitus
<span>FIC Domain Protein Adenylyltransferase (FICD)</span>‐Related Complex Hereditary Spastic Paraplegia with Diabetes Mellitus Open
View article: Antidepressant and neuromodulatory potential of hydroalcoholic extract of <i>Helianthus annuus</i> florets in mouse models of depression
Antidepressant and neuromodulatory potential of hydroalcoholic extract of <i>Helianthus annuus</i> florets in mouse models of depression Open
Background Depression is a pervasive neuropsychiatric disorder having significant social and economic impacts and often linked to imbalances in neurotransmitter systems. Traditional herbal medicines have garnered attention for their potent…
View article: Maternal Awareness and Practice of Child Trauma, Saudi Arabia
Maternal Awareness and Practice of Child Trauma, Saudi Arabia Open
Introduction: Childhood injury is a neglected public health problem with a sizeable burden on children’s well-being and their families. Unintentional injury is one of the leading causes of mortality and morbidity among children. Aim: The c…
View article: The reason why Evidence-Based Practice is important in Nursing
The reason why Evidence-Based Practice is important in Nursing Open
Evidence-Based Practice (EBP) is a universal concept of current nursing that is based on the most recent evidence of the available research, clinical expertise, and patient values to inform the clinical decision-making process. This paper …
View article: Exploring the Influence of Video Games on Self-Reported Spatial Abilities Among University Students
Exploring the Influence of Video Games on Self-Reported Spatial Abilities Among University Students Open
Background: Video games are no longer just entertainment; they are increasingly recognized for their potential to enhance cognitive abilities, including spatial cognition. This skill is vital in academic disciplines, where strong spatial r…
View article: Insights into TLC Profiling, Preliminary Phytochemical Screening, Molecular Docking & Antibacterial Activity of Flavonoid Rich Fraction of Haloxylon persicum
Insights into TLC Profiling, Preliminary Phytochemical Screening, Molecular Docking & Antibacterial Activity of Flavonoid Rich Fraction of Haloxylon persicum Open
View article: Unlocking the biochemical and computational parameters of Ceropegia foetida: A scientific approach for functional bioactive compounds from a medicinal food plant
Unlocking the biochemical and computational parameters of Ceropegia foetida: A scientific approach for functional bioactive compounds from a medicinal food plant Open
Investigating the therapeutic potentials of medicinal plants remains pivotal in the discovery of novel bioactive compounds for food and pharmaceutical applications. This research delves into the phytochemical composition and biological act…
View article: Sesamin’s Therapeutic Actions on Cyclophosphamide-Induced Hepatotoxicity, Molecular Mechanisms, and Histopathological Characteristics
Sesamin’s Therapeutic Actions on Cyclophosphamide-Induced Hepatotoxicity, Molecular Mechanisms, and Histopathological Characteristics Open
Cyclophosphamide, an alkylating agent integral to specific cancer chemotherapy protocols, is often curtailed in application owing to its significant hepatotoxic side effects. Therefore, this study was conducted to assess the hepatoprotecti…
View article: Disposition Kinetics of Cathinone and Its Metabolites after Oral Administration in Rats
Disposition Kinetics of Cathinone and Its Metabolites after Oral Administration in Rats Open
Cathinone is a natural stimulant found in Catha edulis and commonly used in new psychoactive substances. The objective of this study was to examine the disposition kinetics and metabolic profile of cathinone and its metabolite cathine thro…
View article: Hepatoprotective and Antioxidant Effects of Nanopiperine against Cypermethrin via Mitigation of Oxidative Stress, Inflammations and Gene Expression Using qRT-PCR
Hepatoprotective and Antioxidant Effects of Nanopiperine against Cypermethrin via Mitigation of Oxidative Stress, Inflammations and Gene Expression Using qRT-PCR Open
Cypermethrin (Cyp) is a pyrethroid that has been associated with the toxicity of various organs. The aim of our study was to evaluate the hepatoprotective and antioxidant activities of nano-piperine (NP) against Cyp toxicity. Cyp (50 mg/kg…
View article: Explicit mechanistic insights of Prosopis juliflora extract in streptozotocin-induced diabetic rats at the molecular level
Explicit mechanistic insights of Prosopis juliflora extract in streptozotocin-induced diabetic rats at the molecular level Open
View article: Genetic characterization and dissemination of<i>Staphylococcus aureus</i>and Staphylococci genus: food and health perspective
Genetic characterization and dissemination of<i>Staphylococcus aureus</i>and Staphylococci genus: food and health perspective Open
Hospitals and communities are significant hubs for antibiotic-resistant staphylococcal infections, but recently there have been spread of the Staphylococci to other settings including farms and food chains. This study aimed to compare the …
View article: Amphetamine-Related Fatalities and Altered Brain Chemicals: A Preliminary Investigation Using the Comparative Toxicogenomic Database
Amphetamine-Related Fatalities and Altered Brain Chemicals: A Preliminary Investigation Using the Comparative Toxicogenomic Database Open
Amphetamine is a psychostimulant drug with a high risk of toxicity and death when misused. Abuse of amphetamines is associated with an altered organic profile, which includes omega fatty acids. Low omega fatty acid levels are linked to men…
View article: Cinnamon Oil Alleviates Acetaminophen-Induced Uterine Toxicity in Rats by Abrogation of Oxidative Stress, Apoptosis, and Inflammation
Cinnamon Oil Alleviates Acetaminophen-Induced Uterine Toxicity in Rats by Abrogation of Oxidative Stress, Apoptosis, and Inflammation Open
Paracetamol, or acetaminophen (APAP), is one of the first-line medications that is used for fever and pain. However, APAP can induce uterine toxicity when overused. The mode of action of APAP toxicity is due to the production of free radic…
View article: Amphetamine-Related Fatalities and Altered Brain Chemicals: A Preliminary Investigation using the Comparative Toxicogenomic Database
Amphetamine-Related Fatalities and Altered Brain Chemicals: A Preliminary Investigation using the Comparative Toxicogenomic Database Open
Amphetamine is a psychostimulant drug with a high risk of toxicity and death when misused. Abuse of amphetamines is associated with an altered organic profile, which includes omega fatty acids. Low omega fatty acid levels are linked to men…
View article: Trastuzumab-Mediated Cardiotoxicity and Its Preventive Intervention by Zingerone through Antioxidant and Inflammatory Pathway in Rats
Trastuzumab-Mediated Cardiotoxicity and Its Preventive Intervention by Zingerone through Antioxidant and Inflammatory Pathway in Rats Open
Trastuzumab (TZB) is a new medicine, used to treat cancers of the breast and stomach. However, the cardiotoxic potential of this drug edges out its clinical advantages. The present study was designed to find out the effect of zingerone aga…
View article: Magnesium Supplementation Alleviates the Toxic Effects of Silica Nanoparticles on the Kidneys, Liver, and Adrenal Glands in Rats
Magnesium Supplementation Alleviates the Toxic Effects of Silica Nanoparticles on the Kidneys, Liver, and Adrenal Glands in Rats Open
Concerns regarding the possible hazards to human health have been raised by the growing usage of silica nanoparticles (SiNPs) in a variety of applications, including industrial, agricultural, and medical applications. This in vivo subchron…
View article: Design, physicochemical characterisation, and in vitro cytotoxicity of cisplatin-loaded PEGylated chitosan injectable nano / sub-micron crystals
Design, physicochemical characterisation, and in vitro cytotoxicity of cisplatin-loaded PEGylated chitosan injectable nano / sub-micron crystals Open
View article: Capsaicin Ameliorates the Cyclophosphamide-Induced Cardiotoxicity by Inhibiting Free Radicals Generation, Inflammatory Cytokines, and Apoptotic Pathway in Rats
Capsaicin Ameliorates the Cyclophosphamide-Induced Cardiotoxicity by Inhibiting Free Radicals Generation, Inflammatory Cytokines, and Apoptotic Pathway in Rats Open
Cyclophosphamide is an antineoplastic agent that has a broad range of therapeutic applications; however, it has numerous side effects, including cardiotoxicity. Furthermore, chili peppers contain a substance called capsaicin, having antiox…
View article: Neuroprotective Effects of Nano-Curcumin against Cypermethrin Associated Oxidative Stress and Up-Regulation of Apoptotic and Inflammatory Gene Expression in Rat Brains
Neuroprotective Effects of Nano-Curcumin against Cypermethrin Associated Oxidative Stress and Up-Regulation of Apoptotic and Inflammatory Gene Expression in Rat Brains Open
Cypermethrin (CPM) is the most toxic synthetic pyrethroid that has established neurotoxicity through oxidative stress and neurochemical agitation in experimental rats. The toxic effects are supposed to be mediated by modifying the sodium c…